Study of the synthesis of some Indomethacin derivatives

In this research two Indomethacin derivatives were synthesized, Indomethacin ethyl ester was synthesized by The Direct Esterification method by reacting indomethacin with ethanol within different conditions of time, molar ratios and solvents in acidic medium using homogeneous acid catalysts such as sulfuric acid and methane sulfuric acid and heterogeneous acid catalysts such as amberlyst- 15. Then indomethacin acid hydrazide was synthesized by condensing the previous ester with hydrazine hydrate and the best conditions were studied of time, molar ratios, solvents and different temperatures without using any catalyst.

Modification of Chitosan Structure by Using Different Alkyl Chains and Studying of Some its Properties

In this paper, the chemical structure of chitosan has been modified by trans esterification reaction with methyl esters both of octanoic and dodecanoic acid, using potassium carbonate as a based catalyst, the degree of substitution has been determinated to change hydrophilic properties, Some physical properties of trans esterification products has been determined by measuring the Kinematic viscosity, degree of turbidity and density of their water solutions.

Synthesis of Biodiesel from Cotton seed oil using Reactive Distillation column

The transesterification reactions of Cotton seed oil with Methanol using potassium hydroxide as catalyst by Reactive Distillation column, were studied. The ester preparation involved a transesterification reaction, followed by purification.

Synthesis of dodecanoate sodium alginate and study its properties as a carrier of ibuprofen

Tow compounds have been synthesised: tetra butyl ammonium alginate and dodecanoate sodium alginate ester. The synthesis of compound (1) by transferring sodium alginate to Alginic acid and then adjusted by tetra-butyl ammonium hydroxide. The compound (2) was synthesised from tetra-butyl ammonium alginate according to Fisherest erification, between tetra-butylammonium alginate and dodecanoic acid and using (Amberlyst-15) as a hetrogeneous acid catalyst, and then the product react with sodium carbonate.

Kinetics Of Reaction Of 1,10- Decanedioland Dimeric Fatty Acid C36

Kinetic studies were carried out on the reaction between 1,10– Decanedioland dimeric fatty acid C36 in melt phase. The reaction was performed at 140, 150, 160, 170, and 185ºC and followed by determining the acid value of the product.

Enzymatic Preparetion of Sugar Fatty Acid Ester

Sugar fatty acid esters are nonionic surfactants, which are used for personal care products, cosmetic applications, and as emulsifiers for food. In recent years, enzymatic synthesis of sugar fatty acid esters is attracting keen attention as a new manufacturing method for future application. Some Reaction parameters of lipase-catalyzed synthesis of SFAE in organic solvent were optimized in a batch reactor. Optimum conditions for reaction performed were 10% (w/w of substrates) of lipase from Candida antarctica B, at 60°C. Among the solvents tested in this study, the highest yield (93%) was obtained when Aceton was used as a solvent,. The optimal sugar-to-fatty acid ratio was tested in the range from 3:1 to 1:7 and verious sugars were used. A high conversion was obtained when the ratio of Sugar: Fatty acid (1:5) and Froctuse were used as substrat, respectively.