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اصطناع أحد مشتقات الكينوكسالين ودراسة خصائصه البنيوية والضوئية

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 Publication date 2017
  fields Chemistry
and research's language is العربية
 Created by Shamra Editor




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References used
McQuarrie D.A, Simon J.D, Molecular Thermodynamics USA
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تم في هذا البحث تحضیر تسعة مركبات من مشتقات الإندول باستخدام تفاعلات متنوعة مثل الأسیلة والتكاثف الألدولي وتشكیل أسس شیف "الإیمینات"،
In this research two Indomethacin derivatives were synthesized, Indomethacin ethyl ester was synthesized by The Direct Esterification method by reacting indomethacin with ethanol within different conditions of time, molar ratios and solvents in a cidic medium using homogeneous acid catalysts such as sulfuric acid and methane sulfuric acid and heterogeneous acid catalysts such as amberlyst- 15. Then indomethacin acid hydrazide was synthesized by condensing the previous ester with hydrazine hydrate and the best conditions were studied of time, molar ratios, solvents and different temperatures without using any catalyst.
تم في هذا البحث إجراء تفاعلات لبعض الألدهيدات مع ملح فوسفونيوم بنزوتريازول لتحضير مركبات أولفينية للبنزوتريازول
We have synthesized some new compounds from 2-Acetyl Fluorene\ Thiophene 2-carbaldehyde chalcone via condensation and cyclization reactions between the chalcone and each of thiourea and urea, hydroxylamine hydrochloride and hydrazine hydrate, these reactions afford these compounds: 3-(2-fluorenyl)-5-(2-thienyl) pyrazoline(4), 3-(2-fluorenyl)-5-(2-thienyl) Isoxazoline(3), 4-(2-fluorenyl)-6-(2-thienyl) pyrimidinone-2 (2) and 4-(2-fluorenyl)-6-(2-thienyl) pyrimidine-2 tione (1). Also 3-(2-fluorenyl)-5-(2-thienyl) isoxazole (5), were prepared via bromination of chalcon and cyclization the later with hydroxylamine hydrochloride. Identification and determination of compounds structurs were carried out by (IR, 1H-NMR, 13C-NMR, LC-MS) spectrum Analysis.
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