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Register a new userالتعبير عن البروتين المضفر في فيروس التهاب الكبد البائي وقيمته التنبؤية المتوقعة في تقدير إنذار التهاب الكبد البائي المزمن
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Damascus University رسالة ماجستير
Publication date
2013
fields
Pharmacy
and research's language is
العربية
Created by
Shamra Editor
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التعبير عن البروتين المضفر في فيروس التهاب الكبد البائي وقيمته التنبؤية المتوقعة في تقدير إنذار التهاب الكبد البائي المزمن
No English abstract
References used
Baranova A. Lal P, Birerdinc A and Younossi ZM. Ivasive markers for hepatic fibrosis BMC Gastroenterol 2011
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The possible correlation between HLA system and various course of hepatitis B
has been studied in 346 subjects: 277 normal subjects, 27 HBsAg+ patients, 21
post hepatitis B liver cirrhosis patients, and 21 liver cirrhosis without previous
HBV infe
ction patients. Increased frequencies of A23, B21, B51 found in HBsAg+,
A28, B55 in post HBV cirrhosis, and higher frequency of B35 in normal subjects.
Several studies and reports have indicated the prevalence of hepatitis D virus
infection in many parts of the world at different rates , Ranging from areas of
epidemiological and areas with a low prevalence of it.
Till now there is no study in Syr
ia shows us the prevalence of viruse Delta in chronic
hepatitis B patients .
The aim of our study was to determine the current prevalence of hepatitis D in
chronic hepatitis B patients . And to take appropriate measures in dealing with these
patients due to the increased risk of liver disease in the event of injury by it .
77 patients with chronic hepatitis B certainly proved with PCR analysis
25 women and 52 men visiting the center of hepatitis in Latakia were tested for
antibody to hepatitis D virus (anti-HDV) by ELISA test .
The results indicate a positive antibody in three patients (women and 2 men) and the
prevalence was 3.8% , which point to a moderate prevalence of hepatitis D comparing with
neighboring countries.
Hepatitis C is affected by human behaviors especially drugs , diets ,activities
smoking , sexy behaviors and alcohol , so it is very important to change health behaviors
by patient to control of disease and avoid complications .
Objective : to ass
ess the effects of health behaviors on liver function among
hepatitis C patients .Setting :The study was carried out in the Chronic Liver Hepatitis
Center in Alwatany hospitalization in Lattakia province.Subjects::Thesample comprised
40 patients chosen randomly from the two genders who have hepatitis C out in the chronic
liver hepatitis center in Alwatany hospitalization in Lattakia province during the research
time. Tool :Data were collected using the following tools:Tool I Questionnaire: It was
developed by the researcher and include items related to: demographic patients data ,
clinical data , questions about ( patients , information of disease , risk factors, healthy
behaviors : (diet – treatment regimens – activities and habits)) Tool II : Liver function
assessment sheet by using Child Pugh scale.Tool III :Patientcompliance check list which
include questions about complianceGuidenceProshor.guide line has been developed by the
researcherThe patients participated in 3 sessions .Each session (45minutes).Results: liver
function were advanced of patient at the experimental group which applied the guide line
more than patient at the control group because of Appling guide line .Recommendations :
Chronic Liver Hepatitis Centers have been containing proshorsshow the impact of these
health behaviors on the liver work and performing their functions as normal.
إنّ الهدف الأساسي من هذا البحث :
هو تحديد العلامات الجينية لفيروس الالتهاب الكبدي الوبائي (B ) يسمى اختصارا ً ب (HBV ) والذي يكون مرتبط بشكل رئيسي بسرطان الكبد (HCC) وذلك عن طريق ميّزة استخراج المعلومات المفيدة من البيانات كبيرة الحجم التي
تمثل العنصر الرئيسي في مجال المعلوماتيّة الحيويّة Bioinformatics وبشكل رئيسي يتم ذلك من تطوير فكرة مقارنة سلاسل DNA الكاملة ل HBV مع السلاسل الموجودة لدى المرضى الذين يعانون من السرطان الكبدي الوبائي و كذلك المرضى اللذين لا يعانون منه .
إنّ إطار التنقيب عن البيانات data mining framework (الذي نقصد به ِ؛ جمع وتحليل كميّات كبيرة من البيانات لإيجاد علاقة منطقية فيما بينها بحيث تلخّص هذه البيانات بطريقة جيّدة ) يتضمن تحليل التطور الجيني molecular evolution analysis وعملية العنقدة clustering و feature selection وتعليم المصنف classifier learning وعملية التصنيف classification حيثُ سيتم توضيح كيفيّة توظيفها جميعا ً في هذا البحث.
This Study was designed to evaluate the effects of Aloe vacillans leaves juice
on carbon tetrachloride CCl4- induced hepatotoxicity in rats.
Hepatotoxicity was induced in rats by intraperitoneal (i.p) injection of CCl4 (1ml/kg) of body weight every
72h during ethanolic extract of Aloe vacillans
leaves were administrated at dose 250 mg/kg and 500 mg/kg of body weight
pass orally (p.o) daily for 14 days.
Twenty-four hours post-CCl4 treatment, blood samples were withdrawn
through retro orbital sinus.The hepatotoxicity and its prevention was assessed
by serum parameters like alanine aminotransferase (ALT), aspartate
aminotransferase (AST), total protein (T.P) and albumin (ALB).
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