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Register a new userInvestigation of Congenital Hypothyroidism in Newborns and Children at University Children's Hospital in Damascus
استقصاء الإصابة بقصور الدرق الخلقي لدى الولدان و الأطفال في مستشفى الأطفال الجامعي في دمشق
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Aِl-Baath University ورقة بحثية
Publication date
2018
fields
Pharmacy
and research's language is
العربية
Created by
Shamra Editor
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تهدف هذه الدراسة إلى جمع معلومات أكثر عن قصور الغدة الدرقية الخلقي )CH( Congenital Hypothyroidism في سوريا نظرا لكونه واحد من أكثر الأسباب الشائعة للتخلف العقلي و الذي يمكن الوقاية منه في حال تم الكشف عنه و اعطاء المعالجة في وقت مبكر، و لعدم وجود أي بيانات طبية منشورة حوله في بلدنا، و من أجل التأكيد على ضرورة تطبيق برنامج تحري وليدي إلزامي للتشخيص المبكر لقصور الدرق الخلقي لتحسين حياة الطفل.
The aim of this study is to collect more information about Congenital hypothyroidism (CH) in Syria due to it being one of the most common causes of preventable mental retardation if detected at early stage and treatment is preventable, and to the absence of any published statistics regarding it in our country, and to emphasize on the necessity of applying a mandatory newborn screening program for early diagnosis of congenital hypothyroidism to improvement of child’s life, by investigating the adequacy of the clinical determination the physician's experience to get an early diagnosis.
References used
LAFRANCHI, S. and RASTOGI, M., 2010, Congenital Hypothyroidism, Orphanet J Rare Dis., vol. 5, no. 17, 22
VALIZADEH, M., MAZLOOMZADEH, S., NIKSIRAT, A., SHAJARI, Z., 2011, High Incidence and Recall Rate of Congenital Hypothyroidism in Zanjan Province, a Health Problem or a Study Challenge?. Int J Endocrinol Metab., vol. 9, no. 4, 338-342
PEZZUTI, IL., LIMA, PP., DIAS, VM., 2009, Congenital hypothyroidism: the clinical profile of affected newborns identified by the Newborn Screening Program of the State of Minas Gerais, Brazil. J Pediatr (Rio J), vol 85, no. 1, 72-79
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The aim of this study is to evaluate the epidemiology of viral hepatitis in
children in Damascus University children hospital. A retrospective study on
(259) cases of viral hepatitis admitted to hospital within 4 yrs from the
beginning of 2000 to
the end of 2003. The number of hepatitis A virus cases
was (112) cases with an average of 2.9/ 1000 of admissions yearly. More than
a half of cases were between 1-5 years of age. The most common symptoms
and signs were jaundice, fever and hepatomegaly. About 76% of cases were
cured or improved, 21.4% of them were died. For hepatitis B virus the
number of cases was (42) cases with an average of 1.08/ 1000 of admissions
yearly.
Visceral Leishmaniasis is still seen in developing country
To study the epidemiology of Visceral Leishmaniasis cases
hospitalized in Damascus University Children Hospital.
It was retro-spective study on (89) cases of Visceral
Leishmaniasis hospitalized between 1993 and 2005.
Background& Objective: clinical study of patients with Neurofibromatosis I (NFI) in children hospital –
Damascus University
Materials & Methods: All cases of Neurofibromatosis type I in children less than 13 years of age were
identified from the r
ecords in the Department of children, from 2000-2010
They were diagnosed according to a clinical symptoms (café au lait) then complete the diagnosis with
appropriate diagnostic tools.
Hyperimmunoglobulin E (Job) syndrome is considered to be a relatively rare
disease. Its characterized by recurrent infections in skin (eg. boils, abscesses), recurrent upper respiratory
tract infections (eg. otitis media, sinusitis and mastoiditis)
, and lower respiratory infections (eg. recurrent
pneumonia, which is often complicated by pneumatoceles and lung abscess), that are usually difficult to
treat. The highly increased IgE levels are considered to be the hallmark of the disease. The syndrome has
two types: one is inherited as an autosomal recessive, and the other, as an autosomal dominant trait.
To highlight the clinical manifestations and laboratory findigs of Job disease, and to compare it with
medical literature, to study the bacterial complications and differrent types of antibacterial treatments
and treir results, and to increase the level of awareness among physicians.
Background& Objective: Selective IgA deficiency is the most common primary immunodeficiency in
humans. Its prevalence ranges from 1 in 100 to 1 in 1000 in among Arab populations. The majority of
patients with selective IgA deficiency are asymptomat
ic. The remaining present with recurrent upper and
lower respiratory tract infections, recurrent gastrointestinal infections, otitis media, sinusitis, celiac
disease, giardiasis, allergic disorders and some autoimmune diseases.
to highlight the clinical manifestations and laboratory findings of Selective IgA deficiency in our study,
and to compare it with medical literature. To study the bacterial complications and their prevalence.
Materials & Methods: A retrospective study was carried out in Damascus University Children’s Hospital
on sixteen child diagnosed as Selective IgA deficiency, in a period of the last ten years (from 2000 till
September 2010).
Results: most cases in our study were among males, failure to thrive was found in 75%,
hepatosplenomegaly in one third, the most prominent infectious complications were: recurrent pneumonia
(in 87.5% of cases), recurrent GI infections (in 75% of cases) and UTI’s in (50%)of cases. On the other
hand, the celiac disease was found in (25%) of our patients, which is much higher than described in
medical literature. In general, the infectious complications had a good response to antibacterial therapy,
and the IgA levels became normal in one patient, when he reached the age of eleven years.
Conclusion: there is no information in medical literature about the association of selective IgA deficiency
with hepatomegaly, splenomegaly, failure to thrive and an increased prevalence of urinary tract
infections, therefore, it is necessary to conduct researches about this association.
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