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Register a new userInvestigating The relation between Inhaled Corticosteroids and the Occurrence of Oral Candidiasis
تحرّي العلاقة بين استخدام الكورتيكوستيروئيدات الاستنشاقيّة و الإصابة بالمبيضّات البيض الفمويّة
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رشاد مراد( باحث )
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هدفت الدراسة إلى تحرّي العلاقة بين الإصابة بالمبيضّات البيض الفمويّة و العلاج بالكورتيكوستيروئيدات الاستنشاقيّة ، كما هدفت إلى تحرّي تأثير دور الجرعة اليومية في زيادة إنذار الإصابة.
The aim of the study was to investigate the relation between the Occurrence of Oral Candidiasis and Inhaled Corticosteroids (ICS) ، also investigating the role of daily dose in the prognosis .
Artificial intelligence review:
Research summary
هدفت الدراسة التي أجراها الأستاذ المساعد الدكتور رشاد مراد في جامعة دمشق إلى تحري العلاقة بين استخدام الكورتيكوستيروئيدات الاستنشاقية والإصابة بالمبيضات البيض الفموية. تم جمع البيانات من أرشيف مشفى دمشق للفترة بين 2008 و2015، حيث تم تحليل وصفات المرضى الذين تلقوا علاجاً بالكورتيكوستيروئيدات الاستنشاقية. أظهرت النتائج أن 64 من أصل 651 مريضًا بالربو الذين يستخدمون الكورتيكوستيروئيدات الاستنشاقية تلقوا أدوية مضادة للفطريات خلال السنة الأولى من العلاج، مع ارتفاع ملحوظ في نسب الإصابة خلال الأشهر الثلاثة الأولى. كما تبين أن الجرعات اليومية العالية من الكورتيكوستيروئيدات تزيد من خطر الإصابة بالمبيضات البيض الفموية. خلصت الدراسة إلى ضرورة مراقبة المرضى وتثقيفهم حول الاستخدام الصحيح لأدوات الاستنشاق لتقليل الآثار الجانبية غير المرغوبة.
Critical review
دراسة نقدية: تعتبر هذه الدراسة خطوة مهمة في فهم العلاقة بين استخدام الكورتيكوستيروئيدات الاستنشاقية والإصابة بالمبيضات البيض الفموية. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الأفضل تضمين مجموعة مقارنة من المرضى الذين لا يستخدمون الكورتيكوستيروئيدات الاستنشاقية لتحديد الفروقات بشكل أدق. ثانياً، لم يتم التحقق من مدى التزام المرضى بتعليمات الاستخدام الصحيحة لأدوات الاستنشاق، وهو عامل مهم يمكن أن يؤثر على النتائج. أخيراً، كان من المفيد توسيع فترة المراقبة لأكثر من عام للحصول على صورة أوضح عن الآثار الطويلة الأمد لاستخدام الكورتيكوستيروئيدات الاستنشاقية.
Questions related to the research
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ما هو الهدف الرئيسي من الدراسة؟
الهدف الرئيسي هو تحري العلاقة بين استخدام الكورتيكوستيروئيدات الاستنشاقية والإصابة بالمبيضات البيض الفموية، ودراسة تأثير الجرعة اليومية على هذا الخطر.
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ما هي الفترة الزمنية التي تم جمع البيانات خلالها؟
تم جمع البيانات من أرشيف مشفى دمشق للفترة بين عامي 2008 و2015.
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ما هي النسبة المئوية للمرضى الذين تلقوا أدوية مضادة للفطريات خلال السنة الأولى من العلاج بالكورتيكوستيروئيدات الاستنشاقية؟
تلقى 64 من أصل 651 مريضًا، أي حوالي 9.83%، أدوية مضادة للفطريات خلال السنة الأولى من العلاج.
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ما هي التوصيات التي خلصت إليها الدراسة؟
أوصت الدراسة بضرورة مراقبة المرضى وتثقيفهم حول الاستخدام الصحيح لأدوات الاستنشاق لتقليل الآثار الجانبية غير المرغوبة، وخاصة الإصابة بالمبيضات البيض الفموية.
References used
Cicutto، L.، Review: inhaled corticosteroids increase risk of oral candidiasis، dysphonia، and pharyngitis in persistent asthma. Evid Based Nurs، 2007. 10(4): p. 109
Vogt، F.C.، The incidence of oral candidiasis with use of inhaled corticosteroids .Ann Allergy، 1979. 43(4): p. 205-10
Gasser، S. and E. von Elm، [Inhaled corticosteroids in subacute and chronic cough]. Praxis (Bern 1994)، 2013. 102(21): p. 1321-2
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regions.
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The majority of induced abortions (96%) were done surgically by dilatation and evacuation while medication was only used in a small percentage.
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The purpose of this study was to investigate the relation between dental
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A sample of 600 patients was taken randomly
( 322 males - 278 females).
The research was done on patients by giving dental anestheti
c with and
without adrenaline .
The results of the study indicated that:
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xylocaine without adrenaline increased by average of 4% -5% respectively.
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The study concluded 156 patients having thyroid nodes. All the patients checked up
in Assad university hospital in Lattakia between 2008-2012. The majority of patients
having thyroid nodes were 133 females a 85,26% compared to 23 male patients a 14
,74%.
Most patients are young approximatelyin their forties'. 78,21% of patients complained
about having an enormity in the upper side of their necks. All clinical and Ultrasound
examinations were conducted on all patients. The clinical examination was the answer to
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reliable. Fine-Needle Aspiration (FNA) was done for 30 patients and it was directed to 18
patients, but the result was negative for the rest. All tissue samples, which were taken
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The study is also concerned with exploring the relation between the
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and avoiding misconception.
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