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Register a new userMicrobiological Quality control of some herbal medicines
مراقبة جودة بعض المستحضرات الدوائية العشبية من الناحية الجرثومية
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Aِl-Baath University ورقة بحثية
Publication date
2016
fields
Pharmacy
and research's language is
العربية
Created by
Shamra Editor
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تعتبر نقاوة المستحضرات الصيدلانية من الناحية الجرثومية من معايير الجودة الواجب التقصي عنها. تُعد المستحضرات الدوائية العشبية من الأشكال ذات الخصوصية من حيث أن المواد الأولية التي تدخل في تركيبها هي من مصدر طبيعي، و هذا يعني أنيا عرضة لتلوث جرثومي محتمل. يعرف دستور الأدوية المستحضر العشبي بأنه النبات أو الفطر fungi أو الأشنة الكامل أو المجزأ أو أجزاء منه في شكله غير المصنع unprocessed state و غالباٌ بشكله الجاف.
The microbiological limits are considered to be one of the quality criteria that affect pharmaceutical. Herbal drug medicine is of some specialty since their raw material contains a high bioburden. According to pharmacopoeia, Herbal drugs are mainly whole, fragmented or cut, plants, parts of plants, algae, fungi, lichen in an unprocessed state, usually in dried form but sometimes fresh.
Artificial intelligence review:
Research summary
تتناول هذه الدراسة مراقبة جودة بعض المستحضرات الدوائية العشبية من الناحية الجرثومية. تم اختيار أربعة أنواع من الأعشاب وهي القرفة، عرق السوس، الراوند، والسنا، وتم جمع العينات من السوق المحلية في مدينتي النبك وحمص. أظهرت النتائج تلوث بعض العينات بجراثيم سلبية الغرام مثل الإيشريكية القولونية، بالإضافة إلى نمو فطري يتجاوز الحدود المسموحة. تشير الدراسة إلى ضرورة تحسين مراقبة الجودة لهذه المستحضرات لتجنب الأضرار الصحية المحتملة على المستخدمين. توصي الدراسة بضرورة ضبط ورقابة المستحضرات الدوائية العشبية وعدم استجرار المواد الأولية من مصادر غير موثوقة، بالإضافة إلى توسيع نطاق الدراسة لتشمل عينات أكثر تنوعًا.
Critical review
دراسة نقدية: تعتبر هذه الدراسة خطوة مهمة نحو تحسين جودة المستحضرات الدوائية العشبية، إلا أنها تفتقر إلى بعض النقاط التي يمكن تحسينها. أولاً، كان من الأفضل توسيع نطاق العينات لتشمل مناطق جغرافية أوسع لضمان تمثيل أكثر شمولية. ثانياً، لم تتناول الدراسة بشكل كافٍ تأثير طرق التخزين والنقل على جودة المستحضرات، وهو عامل مهم يجب أخذه في الاعتبار. أخيراً، كان من الممكن تضمين توصيات أكثر تحديداً حول كيفية تحسين إجراءات الرقابة والجودة في السوق المحلية.
Questions related to the research
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ما هي الأعشاب التي تم دراستها في هذه البحث؟
تم دراسة القرفة، عرق السوس، الراوند، والسنا.
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ما هي الجراثيم التي تم العثور عليها في العينات؟
تم العثور على جراثيم سلبية الغرام مثل الإيشريكية القولونية بالإضافة إلى نمو فطري.
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ما هي التوصيات التي قدمتها الدراسة لتحسين جودة المستحضرات العشبية؟
أوصت الدراسة بضرورة ضبط ورقابة المستحضرات الدوائية العشبية وعدم استجرار المواد الأولية من مصادر غير موثوقة، وتوسيع نطاق الدراسة لتشمل عينات أكثر تنوعًا.
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ما هي أهمية مراقبة الجودة للمستحضرات الدوائية العشبية؟
مراقبة الجودة مهمة لتجنب التلوث الجرثومي والفطري الذي يمكن أن يسبب أضرارًا صحية للمستخدمين، ولضمان سلامة وفعالية المستحضرات.
References used
aya Bir Karmacharya (2012). Good Manufacturing Practices (GMP) for Medicinal Products, Promising Pharmaceuticals, Dr. Purusotam Basnet (Ed.), ISBN: 978-953-51-0631-9, InTech
(Forty-fourth report of the WHO Expert Committee on specifications for pharmaceutical preparations 2010. (WHO technical report series; no. 957
(Forty-fifth report of the WHO Expert Committee on specifications for pharmaceutical preparations 2011. (WHO technical report series ; no. 961
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