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Pharmacognostic study of Melissa officinalis

دراسة عقاقيريّة في نبات الملّيسة

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 Publication date 2016
  fields Pharmacy
and research's language is العربية
 Created by Shamra Editor




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In October 2014 the collected air-green samples of melissa officinalis were gathered. Then the volatile oil from fresh samples was extracted with N-hexane and other samples with steam distillation. Suitable conditions were chosen to separate the components of the volatile oil by GC-MAS and we noticed : (25) compounds were found in the extracted volatile oil of the first sample ( extraction by N-hexane ). 3 compounds of them are alcohol noncyclic MonoTerpine class and they form 3,46% of the volatile oil weight, 1 alcohol cyclic Monoterpine compound forms 1,83% of the volatile oil total weight, 1 compound from cyclic DeTerpine class and it forms 2.31%, 2 compounds from cyclic MonoTerpine class and they form 3,14%, 2 compounds from Aldyhol group which form 52.03% from the volatile oil's weight. 13 compounds from SesquieTerpine class with a 35,14% of the total weight, 2 Ester compounds and they form 2,12%, and 1 acetic compound which is Lenolenic acid with a 0,97% form the volatile oil total weight.

References used
Melissa officinalis information from NPGS/GRIN". www.arsgrin. gov. Retrieved 2008-03-04
Lemon balm". University of Maryland Medical Center. Apr 5, 2011. Retrieved Oct 18, 2014
Chisholm, Hugh, ed. (1911). "Balm". Encyclopædia Britannica 3 (11th ed.). Cambridge University Press
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The antimicrobial activity of aqueous extract of Zingiber Officinalis were tested for their antifungal activity against the following dermatophytes :Candida albicans, Cladosporium cladosporiosis , Cryptococcus neuphormans, Trichophyton violaceum a nd against other four bacteria : E. coli, Pseudomonas aeruginosa. Staphylococcus aureus, Streptococcus pyogenes. The extract used in traditional medicine for the treatment of nausea was tested in vitro through the Agar Disk Diffusion Method. The minimum inhibitory concentration (MIC) of extracts determined by the Agar dilution method ranged from 1.5 to 12.5 mcg. The most sensitive microorganisms to the extract were Candida albicans with MIC 1.5 and E coli with MIC 1.5 mcg.
In this work Rosmarinus officinalis L. grown in Syria was studied. The general characteristics of the whole plant, as well as the leaves and the flowers were determined. It was shown that there are two varieties of Rosmarinus one having violet flo wers and the other having white flowers. The two varieties were compared morphologically and they were in accord with what was mentioned in the literature. The two varieties were also compared chemically and it was possible to explain the differences mentioned in the literature by differences in the composition of the volatile oil. The chemical study of the drug shows the quantity as well as the percentage of its constituents. At last the main substitute of the drug used in Syria was shown and compared with the main drug. It was shown that the composition of the volatile oil of the substitute is different from the composition of the volatile oil of Rosmarinus, thus it can not be used for the same purpose.
تعد الحصيات الكلوية مشكلة صحية شائعة إذ أن حوالي 5% من النساء و15% من الرجال على الأقل يعانون منها خلال مراحل حياتهم , تستعمل أدوية عشبية ومستحضرات دوائية كثيرة في بلدنا لعلاج هذه الحصيات
In October 2014, the collected air-green samples of Basil herb were gathered from the region of MashtaAlhulu in the ,Then the volatile oil from fresh samples was extracted with N-Hexane and other samples with steam distilled water, and we have found the percentage of the volatile oil in the first sample (N-Hexane) is 2,7% , and 2,5% in the second sample (steam distilled water). Suitable conditions were chosen to separate the components of the volatile oil by GC-MS and we noticed : - the first sample (extracted with N-hexane) contain 18 compounds, and they are: Six Terpenes compounds and they form 21.22%,Hydrocarbon compounds form 21.8% from the total weight and they are 7 compounds, and one compound from Ketone class dicycle and its percentage is 2.32%,and two Ester compound and they form 18.96%, One phenolic compound and forms 21.60%, one Ether compound and forms 14.08%. -the volatile oil from the second sample (extracted with steam distilled water) contains 11 compounds, and they are: 6 compounds belong to Hydrocarbon class and they are the main components in the volatile oil with a 91.24% of the oil total weight, One compoundfrom Ether class forms 1.62%, one phenolic compound which forms 3.93%, and three Terpenes compounds and they form 3.17%.
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