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Register a new userAntimicrobial Activity of Aqueous Zingiber Officinalis Root
الفعالية المضادة الأحياء المجهرية للمستخلص المائي لخلاصة نبات الزنجبيل
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Damascus University ورقة بحثية
Publication date
2005
fields
Pharmacy
and research's language is
العربية
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Shamra Editor
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التأثير المايكروبي للمستخلص المائي لنبات الزنجبيل .اختبـرت فعاليتـة ضـد الفطريـات المبيضات البيض ، المبغثرة ، الشعروية البنفسجية، و المكورات الخبيئة ، مع أربع مـن البكتريـة و هي الإشريكية القولونية و الزائفة الزنجارية و المكورات العنقودية الذهبية و المكورات العقديـة المقيحة. يستخدم الزنجبيل لعلاج القيء في الطب الشعبي و اختبرت فعاليتـه فـي المختبـر باستخدام طريقة الانتشار في الاكار و التركيز المثبط الأدنى بواسطة طريقة تخفيف الاجار إِذْ من تتراوح من 1 إلى 5 إلى 12 مايكرو غراماً و أكثر أنـواع 1 الفطريـات حساسـية هـي المبيضات البيض و التركيز المثبط الأدنى هو 5.1 مايكرو غراماً و البكتريا القولونية و التركيز المثبط الأدنى هو 5.1 مايكرو غراماً.
The antimicrobial activity of aqueous extract of Zingiber Officinalis were tested for their antifungal activity against the following dermatophytes :Candida albicans, Cladosporium cladosporiosis , Cryptococcus neuphormans, Trichophyton violaceum and against other four bacteria : E. coli, Pseudomonas aeruginosa. Staphylococcus aureus, Streptococcus pyogenes. The extract used in traditional medicine for the treatment of nausea was tested in vitro through the Agar Disk Diffusion Method. The minimum inhibitory concentration (MIC) of extracts determined by the Agar dilution method ranged from 1.5 to 12.5 mcg. The most sensitive microorganisms to the extract were Candida albicans with MIC 1.5 and E coli with MIC 1.5 mcg.
References used
Sankaranaruyana jagashri, jolly CL. phytochemical, antibacterial and pharmacological investigations on momordica charatia Linn Lmblica officinali Gaer tn and curuma linn Indian.3.pharma.sci (1) 6-13-1993
Czech Erich, kneife wolfgang, koop Brigitte. Microbiological status of commercially available medicinal herbal drugs as screening study. Plant.med.67,263-269.2001
Altman RD,marcussenck. Effects of aging extract on knee pain in patients osteoarthritis , Arthritis,rhem; 44(11);2531-2538.2001
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The antibacterial activity of Golden henbane (Hyoscyamus aureus) on
several species of bacteria: Pseudomonas aeruginosa, Staphylococcus
aureus and Escherichia coli was determined. Samples of H. aureus
plants were collected from six locations in southern Syria. The extract
of roots and leaves of H. aureus were prepared at concentrations.
Background& Objective: This research is carried out to investigate the Anti-inflammatory activity of the alcoholic extract of flower buds of Crataegus laevigata in experimentally-induced arthritis in rats.
Materials & Methods: the inflammation was i
nduced experimentally by Carrageenan, the standard material that causes non-immune acute inflammation. The size of edema was measured before and after the inducing the inflammation, in control group as well as in group treated by extract and by Diclofenac.
The measurements persist until the 4th hour following the injection of Carrageenan. In another set of experiment, the important biomarker, TNF-α, was calibrated in inflammation-induced groups of rats that received extract or Diclofenac and compared with control.
Results: The extract significantly reduced the size of edema compared with control and this effect was not less than that of Diclofenac, the standard anti-inflammatory drug. Indeed, the extract lowered the values of TNF-α.
Conclusion: The Crataegus laevigata has clear anti-inflammatony effect , but it should be further investigated.
We aimed in this study to evaluate the effectiveness of Syrian propolis on some bacterial strains isolated from Al-Assad hospital in Latakia, to estimate its antimicrobial activity. Thus, we studied two propolis samples from two regions in the Syrian
coast, and prepared ethanolic extracts of propolis (EEP) with different concentrations (0.5%, 1%, 5%, 10%, and 20%). Then we tested these extracts on four strains of bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Acinetobacter baumannii), using pore method on Muller Hinton Agar. As we observed, the bacteria showed diverse susceptibility to the extracts and the most susceptible bacterium was Staphylococcus aureus which was sensitive to all concentrations and especially for EEP 20%. However, the least affected bacteria were E. coli and Pseudomonas, as the 0.5% and 1% EEP had no efficacy. On the other hand, there were little differences in antimicrobial activity between the two samples of propolis.
Samples of Trout dived into aqueous extract of ginger in different
concentrations (5-15-25)% for one minute and then preserved at 4±1
cº for 13 days. It has studied the effect of aqueous extract of ginger
in bacterial load, including general bacterial census and the census
of pseudomonas. It was also identified the values of the pH and
some organoleptic qualities of meat such as color, smell, texture and
taste.
The antibacterial activity of Inula viscosa L. leaves extracts against some pathogenic bacteria, which were isolated from Al-Assad hospital laboratory in Lattakia, was tested by disc diffusion method.
Results showed that water extracts had antibacte
rial activity against all Gram positive and negative bacteria. The diameters of inhibition zones were between 9 mm against Pseudomonas aeroginosa and 41 mm against Proteus vulgaris.
All Gram positive bacteria showed sensitivity to all organic extracts, so they had antibacterial activity, while Gram negative bacteria showed resistance to chloroform extract except for the one of Klebsiella pneumoniae with an inhibition zone of 12 mm, and resistance for dichlormethan extract except for Pseudomonas aeruginosa with an inhibition zone of 15 mm. there was resistance for diethyl extract except for Serratia marcescens with an inhibition zone of 32 mm.
Ethyl acetate extract had antibacterial activity against all bacteria. Ethanol, methanol and acetone extracts showed antibacterial activity against all bacteria except for Escherichia coli with an inhibition zone of 10 mm.
This study indicated that water and organic Inula viscosa L. leaves extracts had antibacterial activity against pathogenic bacteria which also was tested, especially water extract, ethanol, methanol, ethyl acetate and hexane extracts. So the Inula viscosa L. leaves extracts may be sources for natural antibiotic in future.
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