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Register a new userEvaluation of a Four Color Protocol for Diagnosis of Pediatrics Acute Leukemia
تقييم الأهمية التشخيصية لمجموعة من المستضدات الخلوية في تشخيص ابيضاض الدم الحاد عند الأطفال
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Damascus University ورقة بحثية
Publication date
2009
fields
Medicine
and research's language is
العربية
Authors
إلهام حرفوش( باحث )
Created by
Shamra Editor
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يؤدي التنميط المناعي للخلايا دوراً مهماً في تشخيص آفات الدم الخبيثة. على أن التشخيص الدقيق للحالة الابيضاضية يعتمد على الاختيار الملائم لأضداد المستضدات السطحية. الهدف: تقييم الأهمية التشخيصية لمجموعة من المستضدات الخلوية السطحية و السيتوبلاسمية في ابيضاضات الدم الحادة عند الأطفال.
Flow cytometry became unavoidable step in the diagnosis of Acute Leukemia . However, accurate diagnosis is conditioned by using proper markers. Objective: to evaluate the quality of performance of four colors protocol, we used for immunophenotyping of acute leukemia in children.
References used
Einsiedel HG et al,.Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse. J Clin Oncol. 2008 May 1;26(13):2238
Winter, S. et al., Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood . 2007, 110: 1429
Pui CH, et al, Childhood and adolescent lymphoid and myeloid leukemia. Hematology Am Soc Hematol Educ Program. 2004:118-45
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