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Register a new userTumors of Hair Follicles A Retrospective Histological Study in Dermatology Department Damascus University
أورام الجريبات الشعرية دراسة نسجية استعادية بمشفى الأمراض الجلدية-جامعة دمشق
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Damascus University ورقة بحثية
Publication date
2009
fields
Medicine
and research's language is
العربية
Authors
لينة الحاج إبراهيم( باحث )
Created by
Shamra Editor
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هدف البحث: تقييم العلامات السريرية التشريحية المرضية لأورام الجريبات الشعرية. شملت هذه الدراسة ( 35 ) مريضاً مصابين بأورام الجريبات- الشعرية، راجعوا مشفى الأمراض الجلدية و الزهرية – جامعة دمشق خلال عامين: ( 2007 2008 ) و قد أجريت دراسة راجعة لملفات هؤلاء المرضى مع إعادة الفحص لشرائحهم النسجية.
Objective: to assess the clinicopathologic features of tumors of the hair follicles. This study included 35 patients with tumors of the hair follicles seen at dermatology and venereology hospital at Damascus university during 2 years (2007-2008). A retrospective study of patient's files and re-examination of their histological slides were done.
Artificial intelligence review:
Research summary
تهدف الدراسة إلى تقييم العلامات السريرية والتشريحية المرضية لأورام الجريبات الشعرية. شملت الدراسة 35 مريضاً (20 أنثى و15 ذكراً) تتراوح أعمارهم بين 10 و65 سنة، وقد راجعوا مشفى الأمراض الجلدية والزهرية بجامعة دمشق خلال عامي 2007-2008. أظهرت النتائج أن نسبة الإصابة بأورام الجريبات الشعرية بلغت 22.43% من إجمالي أورام لواحق البشرة. تضمنت الدراسة أنواعاً مختلفة من الأورام مثل ورم المطرس الشعري، الورم الظهاري الشعري، الورم الأرومي الشعري، ورم غمد جذر الشعرة، والورم الليفي المحيط بالجريب. كان ورم المطرس الشعري هو الأكثر شيوعاً بنسبة 51.42%. تركزت الأورام بشكل رئيسي في منطقة الرأس والعنق. خلصت الدراسة إلى أن أورام الجريبات الشعرية تعتبر أوراماً عابية سليمة في معظم الحالات، ولكن قد تشير إلى احتمالية تطور أورام وسرطانات داخلية عند تعددها.
Critical review
دراسة نقدية: تعتبر هذه الدراسة مهمة في مجال الأمراض الجلدية، حيث تسلط الضوء على أنواع مختلفة من أورام الجريبات الشعرية وتوزيعها النسيجي والتشريحي. ومع ذلك، يمكن تحسين الدراسة من خلال زيادة حجم العينة لتشمل عدد أكبر من المرضى، مما قد يساعد في الحصول على نتائج أكثر دقة وشمولية. كما أن الدراسة تعتمد على بيانات استعادية، وهو ما قد يؤثر على دقة النتائج. بالإضافة إلى ذلك، لم تتناول الدراسة بشكل كافٍ العوامل الوراثية والبيئية التي قد تساهم في تطور هذه الأورام.
Questions related to the research
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ما هي نسبة الإصابة بأورام الجريبات الشعرية مقارنة بأورام لواحق البشرة الأخرى؟
نسبة الإصابة بأورام الجريبات الشعرية بلغت 22.43% من إجمالي أورام لواحق البشرة.
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ما هو الورم الأكثر شيوعاً بين أورام الجريبات الشعرية؟
ورم المطرس الشعري هو الأكثر شيوعاً بنسبة 51.42%.
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ما هي الفئة العمرية الأكثر عرضة للإصابة بأورام الجريبات الشعرية؟
تتراوح أعمار المرضى بين 10 و65 سنة، مع وسطي عمر عند التشخيص يبلغ 26 سنة لورم المطرس الشعري.
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أين تتركز أورام الجريبات الشعرية بشكل رئيسي؟
تتركز أورام الجريبات الشعرية بشكل رئيسي في منطقة الرأس والعنق.
References used
R. Restrepo .E .Calonje . Diseases of the hair in : Pathology of the skin with Clinical correlation . Third Edition . Elsevier Ltd , 2005 , 20.1063 – 1067
Sperling , L.C.Hair anatomy for the Clinician . J .Am Acad Dermatol ( 1991 ), 25, 1– 7
Thomas Brenn , Phillip H Mckee. Tumors of the hair follicle in : Pathology of the skin with Clinical correlation , Third Edition . Elsevier Ltd , 2005 , 27 , 1519 , 1563
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This retrospective study is to correlate oral squamous cell carcinoma with age,
gender and location of lesion, and to investigate the correlation between the grade of the malignancy and
lymph nodes in patients of the faculty of dentistry, Damascus university.
It is a retrospective study of peripheral cemento-ossifying fibroma for patients
of the faculty of dentistry – Damascus university, and a histological comparative study of the collageneous
and mineralized constituents between the lesions of the maxilla and mandible.
Cysts are more frequent in jaws comparing to other body bones, although their
treatment is simple and depends on surgical approach as a first choice, still they are important due to
their clinical complication.
The aim of this retrospective study
is to determine the percentage of radicular, dentigerous, odontogenic
keratocysts and non-odontogenic cysts percentage in Damascus, Syria, and comparing these results with
previously recorded records from other countries.
Background& Objective: Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and
non-dermatophyte molds. Far more than being a simple cosmetic problem, infected nail serves as a
chronic reservoir, which can give rise to repeated
mycotic infections.
This study aim to identify the common fungal species which are responsible for onychomycosis in
clinically suspected patients of onychomycosis in Dermatology and Venereal Diseases Hospital in
Damascus between October 2010 and July 2011.
Materials & Methods: Both direct microscopy and culture of the nail material were performed to identify
the causative fungi of onychomycosis.
Results: Culture positivity was obtained in 65 of the 76 clinically suspected samples, etiological fungal
agents were (%61.5) dermatophytes, (24.6%) yeasts, and (13.9 %) non-dermatophyte molds . The isolated
fungal species were (43.1%) Trichophyton Rubrum and (16.9%) T. Interdigitale (1.5%) T.Verrucosum
Aspergillus Versicolor which was the most frequent non dermatophyte molds. Females were affected in
fingernails more frequently than males, while males were affected in toenails more frequently than
females, and in both sexes those most infected were between 20-40 years of age.
Conclusion: Dermatophytes, in particular T. rubrum, but also T. Interdigitale, are the most frequently
isolated causative agents in onychomycosis in patients seen in Dermatology and Venereal Diseases
Hospital in Damascus . In addition, yeasts may be isolated relatively frequently, while molds are
uncommon.
the fibroma's correlation with age, gender and the location of lesion, and then to conduct an analytical study of the collagenous and mineralized constituents between the lesions of the maxilla and mandible for the patients of the faculty of dentistr
y, Damascus university.
Methods & Materials: Our study covered 36 patients aged 9 – 40 years, (average 24.5 years old), 12 males and 24 females. Central cemento-ossifying fibroma was diagnosed and treated at maxillofacial surgery department, the oral histology and oral pathology department, faculty of dentistry, Damascus university,
between 2004 and 2008. Biopsies were studied after they had been stained with hematoxylin and eosin.
The analytical tables were made using SPSS program, issue 13.0 and Chi square test for Sig<0.05.
Results: The clinical examination of the tumor showed hard swelling covered by normal mucosa. The
proportion of tumors in females was 2:1 for males in the third decade of life. 58.3 of lesion were in the
mandible mainly in premolars and molars. The histological study showed fibrous connective stroma of bundles of collagenous fibers including fibroblasts and mineralized materials either osseous, osteoid or cementoid. Bundles of collagenous fibers formed 55.6% of fibrous connective. The ratio of laminar bone
trabeculae was varied between 40% for the maxilla and 67% for the mandible. Osteoid material existed by 60% in the maxilla and 33% in the mandible. 90.5% of mandibular tumor compared with 73% of that of the maxilla were surrounded by a true complete connective capsule. The statistics study showed a
correlation between the mineralized materials and the location of lesion Sig<0.05.
Conclusion: central cemento-ossifying Fibroma appeared much greatly in females of thirties and it trended to defeat the mandible more than the maxilla. There was an important correlation between the mineralized materials and the location of lesion.
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