113 psoriatic patients participated in the study. The patients were selected from the Dermatology and Venereology department at Alasad hospital in Lattakia city between 2012-2013 years. Mycological examination was carried out in all patients showing
psoriatic nail changes .The aim of the study is to evaluate : the frequency of nail changes in psoriatic patients, the frequency of onychomychosis in patients with nail psoriasis and the factors that may have a role in the incidence of onychomcosis in patients with nail psoriasis.
Nail changes were seen in (61.9%) of psoriatic patients (70 patients). Positive mycological cultures were obtained from 34 patients (48.6%). There was an increase of the incidence of onychomycosis in patients with high levels of NAPSI and long duration of psoriasis and nail psoriasis. There was a relationship between onychomycosis and the age of the patient. We found an increase of the incidence of onychomycosis among the patients who had a systemic therapy for psoriasis (methotrexate,cyclosporine) and the patients who had a history of contusion on nails. There was no relationship between onychomychosis and the gender of the patient.
This study confirmed that onychomycosis may occur in patients with nail psoriasis
Background& Objective: Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and
non-dermatophyte molds. Far more than being a simple cosmetic problem, infected nail serves as a
chronic reservoir, which can give rise to repeated
mycotic infections.
This study aim to identify the common fungal species which are responsible for onychomycosis in
clinically suspected patients of onychomycosis in Dermatology and Venereal Diseases Hospital in
Damascus between October 2010 and July 2011.
Materials & Methods: Both direct microscopy and culture of the nail material were performed to identify
the causative fungi of onychomycosis.
Results: Culture positivity was obtained in 65 of the 76 clinically suspected samples, etiological fungal
agents were (%61.5) dermatophytes, (24.6%) yeasts, and (13.9 %) non-dermatophyte molds . The isolated
fungal species were (43.1%) Trichophyton Rubrum and (16.9%) T. Interdigitale (1.5%) T.Verrucosum
Aspergillus Versicolor which was the most frequent non dermatophyte molds. Females were affected in
fingernails more frequently than males, while males were affected in toenails more frequently than
females, and in both sexes those most infected were between 20-40 years of age.
Conclusion: Dermatophytes, in particular T. rubrum, but also T. Interdigitale, are the most frequently
isolated causative agents in onychomycosis in patients seen in Dermatology and Venereal Diseases
Hospital in Damascus . In addition, yeasts may be isolated relatively frequently, while molds are
uncommon.
