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Register a new userThe efficacy of using Trypsin in treatment of dry socket
فعالية استخدام التريبسين في علاج التهاب السنخ الجاف
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زافين قره بيت( باحث )
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المراجعة النظرية: نظراً للخصائص التي يمتلكها التريبسين كأنزيم فعال في معالجة الجروح هدفت هذه الدراسة تقييم فعالية هذه المادة في معالجة التهاب السنخ الجاف بالمقارنة مع المعالجات التقليدية. المواد و الطرائق: أنجزت الدراسة على 132 مريض تراوحت أعمارهم بين 20-65 سنة تم تقسيمهم على مجموعتين عشوائيا. عولجت المجموعة الأولى بالتريبسين و عولجت المجموعة بالطريقة التقليدية. شوهد المرضى بعد 24 ساعة ،48 ساعة ،بعد أسبوع من تطبيق العلاج لتقييم تطور الشفاء. النتائج:نسبة الألم في المجموعة الأولى 43.9 %, أما المجموعة الثانية 10,6% (p<0.05).
Due to it`s several properties of Trypsin as an active enzyme in treating wounds, the aim of this study was to evaluate the efficacy of this material with traditional treatments in treating dry socket. Methods:132 patients (20-65 years old) participated in this study. The patient were distributed randomly into two groups. The first group (group 1) was treated with Trypsin whereas the other (group 2) was treated with traditional technique . Patients were monitored, to asses healing process, after 24 hours, 48 hourse, and after 1 week. Results: 43,9% of group 1 and 10,6% of group 2 had no pain P<0,05,wereas 81,8% of group 1 and 43,9% of group 2 didn`t present dry socket P<0,05. Concerning infection ,7 cases of group 1 and 11 cases of group 2 had infection of soft tissue P<0,05. Conclusions :Pain, dry socket, and soft tissue infection was less in casese treated with Trypsin comparing with cases treated with traditional technique.
References used
ABU YOUNIS MH, ABU HANTASH RO. Dry socket: frequency, clinical picture, and risk factors in a palestinian dental teaching center. Open Dent J. 2011 Feb 7;5:7-12
RAVIKUMAR T, RAMAKRISHNAN M, JAYARAMAN V, BABU M. Effect of trypsin-chymotrypsin (Chymoral Forte D.S.) preparation on the modulation of cytokine levels in burn patientsBurns. 2001 Nov;27(7):709-16
BLUM IR. Contemporary views on dry socket (alveolar osteitis): a clinical appraisal of standardization, aetiopathogenesis and management: a critical review. Int J Oral Maxillofac Surg. 2002 Jun;31(3):309-17
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The study included 480 patients , 260 males and 220 females who have 920
teeth to beextracted.
The ages of patients were ranging from 20 to 40 years.
In each group the teeth were divided according to its location , Mandible,
Maxillary, anterior o
r posterior.
The extractions were symmetric .Socketol was used in one side while was
not used in the other side..
Patients were recalled after 24 hours 36 hours,48 hours and 72 hours .
Dry socket was determined by the symptoms and signs.
the sample consisted of 36 patients who were admitted in alassad and tishreen
hospital between 2013-2016 with bacterial arthritis proved by clinical,radiological and
laboratory methods. They went uder surgical intervention ,during it,a continuous i
rrigation
system was accomplished according to designed plan. The irrigation period was 12 days
(mean) with mean hospitalization period 12 days. Irrigation fluid was considered regarding
to culture and susceptibility results in addition to antibiotic qualities .Results were
collected depending on joint functional activitiy return regarding to capacity,bearing and
stability(after a month-3 months- year),as well as natural laboratory and vlinical features
return .we used the criteria healing (irrigation handout). The joint functional activity
returned after a month in (70% mean) ,after 3 months in (77% mean), after a year in (89%
mean).while the clinical infection signs fell back after a week in (85% mean) ,after a
month in (92% mean), after 3 months in ( 97%). The laboratory signs fell back after a
month in (91% mean), after 3 months in (97% mean). A comparing was achieved between
these results and irrigation period ,hospitalization period by using CHI² test . The use of
continuous irrigation system in treatment of bacterial arthritis once it is diagnosed (in
regard to designed plan, irrigation fluid qualities and the host condition) improves the joint
functional activity and reduces hospitalization period so that ,it lessens economic load and
accelerates the return professional activity.
The objective of this study was to compare Chlorhexidine gel 0,2%
with Clindamycine phosphate gel 1% when they applied topically
to protect of pain and dry socket after surgical extraction.
The aim of this study is to compare the efficacy of doxycyclin vs.systemic
isotretinoin in the treatment the second and third forms of rosacea, 50 patients aged
between 22 - 61 years of patients who had a second type II and type III of Rosecea with
at
least eight inflammatory lesions were divided into 2 groups of 25, The first was treated
with isotretinoin and the other with doxycycline. The effectiveness of both treatments was
compared, in addition, the side effects between the two treatments.
Results: In general, there were no significant difference between the 2 drugs in The
number of Papules and pustules, the severity of the erythema and Rhinophyma.
In both groups there was a clear relation between the treatment and DLQI . For side
effects, The results shown that 18 patients in the group of isotretinoin therapy had side
effects and no side effects were observed for patients treated with doxycycline.
Conclusion: The study concluded that isotretinoin therapy had similar efficacy to
doxycycline therapy.
The primary goal of any surgery for cholesteatoma is complete
eradication of this lesion aiming to reach a dry ear and to prevent the
complications and recurrence. The second goal is to preserve hearing or to
improve it. This study aims to discuss
cases of Cholesteatoma treated by
canal wall-up mastoidectomy (Closed technique) and to determine the
efficacy of this technique by studying the recurrence rates and hearing
results.
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