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Register a new userThe transcription factor Zfhx1a is expressed in the embryonic chick spinal cord glial cells
التعبير عن عامل الانتساخ Zfhx1a في الخلايا الدبقية للنخاع الشوكي في جنين الدجاج
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شادي سكرية( باحث )
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في ذبابة الفاكهة، يعبر عن عوامل الانتساخ Zfh, الحاوية على إصبع الزنك و المجال المثلي، في العديد من الأنسجة بما فيها الجهاز العصبي.
In Drosophila, the zing-finger homeodomain transcription factors zfh are expressed in many tissues including nervous system.
References used
Fortini ME, Lai ZC, Rubin GM, 1991. The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs. Mech Dev, 34(2-3):113-122
Postigo AA, Ward E, Skeath JB, Dean DC, 1999. zfh-1, the Drosophila homologue of ZEB, is a transcriptional repressor that regulates somatic myogenesis. Mol Cell Biol, 19(10):7255-7263
Thiery JP, 2003. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol, 15(6):740-746
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This research aims at establishing
and testing protocols for isolation, in vitro proliferation, phenotyping, and
differentiation of MSCs embedded in umbilical cord tissues of Syrian
newborns.
MSCs were isolated from two caesarian births depending
on their
adherence characteristic on plastic surfaces, and cells were cultured in MSC
medium for their growth and proliferation. Cell phenotyping was performed by
flow cytometry using fluorescent monoclonal antibodies specific to MSCs’
surface markers. Cultured cells were passed several times and a portion of
these cells was cryopreserved in liquid nitrogen, and cell viability was assessed.
Differentiation of these MSCs into adipocytes was conducted using culture
medium Indomethacin and hydrocortisone.
Serum response factor (SRF) is a protein that regulates the transcription of
several other genes. It regulates especially cardiovascular system
developmental regulatory genes.
This study which was based on the immunohistochemistry showed that
SRF
influence the brain and limb vasculature development in the mice embryo.
The goal of this research is to study the expression of epidermal and
transforming growth factor receptor in normal human bone marrow (BM)
cell, and in leukemia ( myeloid and lymphatic leukemia ) which promoted
the research for the function of EGF
R receptors in the development and
growth of BM cells and for malignancies expressing of the EGFR as
potential therapeutic targets in blood cell malignant diseases.
Cancer stem cells in solid tumors are a "rare" group of cells and
their role in carcinogenesis has been proven during the past few
years. The pursuit for specific oral epithelial stem cell surface
markers leads to the identification of markers su
ch as CD44
and Bmi-1. The combination between CD44 which has been
considered a potential prognostic marker for cancer stem cells in
Head and Neck Squamous Cell Carcinoma (HNSCC), and Bmi-1
the pluripotency stemness marker may lead to identify the cells
sharing the properties of both markers and could give a closer look
into its appearance and density in the tissue. The aim of this study
was to study the percent of cells stained positive for both markers
and the histological grade of (HNSCC) and the anatomic location
of the tumor. Statistical analysis showed that higher density of
positive stained cells for both markers was in the severe grade of
the tumor, whereas the second higher ratio was in the mild grade
then the moderate , there was no significant association between the density of cells and the anatomical location. Our results suggest that the two markers together could be used as prognostic factors for patients with even mild grade SCC, which might help in prediction of recurrence.
This study has been conducted to adapt a quantitative RT-QPCR to
detect the least amount of virus and tissue culture pathogenic dose
(TCID50) of CAEV showed cytopathogenic effect (CPE) from
clinical samples.
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