The aim of this clinical study compared the use of normal
saline versus (PVP-I) as Irrigating solution during bone
removal on the following edema of The surgical extraction of
the lower third molar impacted.
The increasing number of individuals with diabetes suggests that diabetic retinopathy DR is
a major contributor to vision loss. The initial disease is characterized by increased vascular
permeability due to a breakdown in the blood-retinal barrier
BRB, causing macular edema DME,
with a progressive vascular occlusion and retinal neovascularization which are secondary to
ischemia and oxidative stress. Laser photocoagulation and vitrectomy only target advanced stages
of disease. However, despite laser treatment, patients with DME experienced gradual loss of
vision. Intravitreal triamcinolone IVTA reduces the breakdown of BRB and down-regulates the
production of vascular endothelial growth factor VEGF. IVTA may moderately but temporarily
improves visual acuity in cases of DME. Agents that attenuate VEGF action such as bevacizumab
are expected to reduce permeability and neovascularization. Intravitrealbevacizumab IVB reduces
macular edema secondary to central retinal vein occlusion, vascular permeability and fibrovascular
proliferationin. Calcium dobesilate CD is a potent antioxidant, slows vascular proliferation.
Although the use of Soft Laser appliances has become common in dental
practice especially in the field of oral and maxillofacial surgery as an
important method for controlling the edema that may occur after oral and
maxillofacial surgery (as said
by the manufacturing companies ),there
are just a few neutral researches that deal scientifically with this subject, so
that is our motive to do in this research .In this study, and between May
1996 and May 2003, 80 patients were carefully selected so 160 lower third
molars were surgically extracted , the soft laser was applied on the left side
and after that the results compared with the results of the right side
operations which were not subjected to any method for controlling edema.
The results were disappointing and the great advantages that were
confirmed by the manufacturing companies were not true while the neutral
comparative research emphasized that the usage of Soft laser treatment has
no magical effect in reducing or preventing the occurrence of severe edema
after the surgery of impacted lower third molars , so we want to warn every
dentist to be careful when reading a research sponsored by the
manufacturing companies of Soft laser appliances.