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The increasing number of individuals with diabetes suggests that diabetic retinopathy DR is a major contributor to vision loss. The initial disease is characterized by increased vascular permeability due to a breakdown in the blood-retinal barrier BRB, causing macular edema DME, with a progressive vascular occlusion and retinal neovascularization which are secondary to ischemia and oxidative stress. Laser photocoagulation and vitrectomy only target advanced stages of disease. However, despite laser treatment, patients with DME experienced gradual loss of vision. Intravitreal triamcinolone IVTA reduces the breakdown of BRB and down-regulates the production of vascular endothelial growth factor VEGF. IVTA may moderately but temporarily improves visual acuity in cases of DME. Agents that attenuate VEGF action such as bevacizumab are expected to reduce permeability and neovascularization. Intravitrealbevacizumab IVB reduces macular edema secondary to central retinal vein occlusion, vascular permeability and fibrovascular proliferationin. Calcium dobesilate CD is a potent antioxidant, slows vascular proliferation.
Pretreatment is one of the most important stage in olive mill wastewater (OMWW) plants. Statistically, the cost of chemicals in pretreatment will be not more than 0.02 €/m³OMWW for some kind of chemical coagulants such as CaO.
This research focused on one of the stages of the conventional treatment of water in the purification stations, a process of coagulation, which enhanced by using alternatives to alum; such as Ferric Chloride and Poly Aluminum-chloride (PACl), whic h play an important role to reducing the turbidity of drinking water through the destabilization of colloids, which include organic and inorganic materials in order to increase the efficiency of sterilization and disposal of the side effects of sterilization (DBPS) and to minimize the problems of clogged sand filters due to an increase of the turbidity of water inside it. According to that, three types of coagulant agents were used for the purpose of comparison with each other to achieve the best efficiency in the process of reducing water turbidity through a process of coagulation improved by using (Jar-test). Different concentrations of coagulant agents of irrigation water were used depending on experiments. The results found that urinary chloride aluminum gave the highest efficiency in reducing turbidity by (84, 82 and 81%) according to the addition of concentration for coagulation (20 ppm, 10 ppm and 5ppm), respectively. The reduction rates in turbidity for Ferric chloride were (79, 78.2 and 78.1% ) by concentrations added, respectively, but for alum, the reduction rates in turbidity were (58, 56, and, 54%) by concentrations added, respectively.
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