Objective
This research aimed to describe several areas in which AI could play a role in the development of Personalized Medicine and Drug Screening, and the transformations it has created in the field of biology and therapy. It also addressed the l
imitations faced by the application of artificial intelligence techniques and make suggestions for further research.
Methods
We have conducted a comprehensive review of research and papers related to the role of AI in personalized medicine and drug screening, and filtered the list of works for those relevant to this review.
Results
Artificial Intelligence can play an important role in the development of personalized medicines and drug screening at all clinical phases related to development and implementation of new customized health products, starting with finding the appropriate medicines to testing their usefulness. In addition, expertise in the use of artificial intelligence techniques can play a special role in this regard.
Discussion
The capacity of AI to enhance decision-making in personalized medicine and drug screening will largely depend on the accuracy of the relevant tests and the ways in which the data produced is stored, aggregated, accessed, and ultimately integrated.
Conclusion
The review of the relevant literature has revealed that AI techniques can enhance the decision-making process in the field of personalized medicine and drug screening by improving the ways in which produced data is aggregated, accessed, and ultimately integrated. One of the major obstacles in this field is that most hospitals and healthcare centers do not employ AI solutions, due to healthcare professionals lacking the expertise to build successful models using AI techniques and integrating them with clinical workflows.
Coreference resolution is key to many natural language processing tasks and yet has been relatively unexplored in Sign Language Processing. In signed languages, space is primarily used to establish reference. Solving coreference resolution for signed
languages would not only enable higher-level Sign Language Processing systems, but also enhance our understanding of language in different modalities and of situated references, which are key problems in studying grounded language. In this paper, we: (1) introduce Signed Coreference Resolution (SCR), a new challenge for coreference modeling and Sign Language Processing; (2) collect an annotated corpus of German Sign Language with gold labels for coreference together with an annotation software for the task; (3) explore features of hand gesture, iconicity, and spatial situated properties and move forward to propose a set of linguistically informed heuristics and unsupervised models for the task; (4) put forward several proposals about ways to address the complexities of this challenge effectively.
Resolving pronouns to their referents has long been studied as a fundamental natural language understanding problem. Previous works on pronoun coreference resolution (PCR) mostly focus on resolving pronouns to mentions in text while ignoring the exop
horic scenario. Exophoric pronouns are common in daily communications, where speakers may directly use pronouns to refer to some objects present in the environment without introducing the objects first. Although such objects are not mentioned in the dialogue text, they can often be disambiguated by the general topics of the dialogue. Motivated by this, we propose to jointly leverage the local context and global topics of dialogues to solve the out-of-text PCR problem. Extensive experiments demonstrate the effectiveness of adding topic regularization for resolving exophoric pronouns.
We introduce the new task of domain name dispute resolution (DNDR), that predicts the outcome of a process for resolving disputes about legal entitlement to a domain name. TheICANN UDRP establishes a mandatory arbitration process for a dispute betwee
n a trade-mark owner and a domain name registrant pertaining to a generic Top-Level Domain (gTLD) name (one ending in .COM, .ORG, .NET, etc). The nature of the problem leads to a very skewed data set, which stems from being able to register a domain name with extreme ease, very little expense, and no need to prove an entitlement to it. In this paper, we describe thetask and associated data set. We also present benchmarking results based on a range of mod-els, which show that simple baselines are in general difficult to beat due to the skewed data distribution, but in the specific case of the respondent having submitted a response, a fine-tuned BERT model offers considerable improvements over a majority-class model
Relevance in summarization is typically de- fined based on textual information alone, without incorporating insights about a particular decision. As a result, to support risk analysis of pancreatic cancer, summaries of medical notes may include irrel
evant information such as a knee injury. We propose a novel problem, decision-focused summarization, where the goal is to summarize relevant information for a decision. We leverage a predictive model that makes the decision based on the full text to provide valuable insights on how a decision can be inferred from text. To build a summary, we then select representative sentences that lead to similar model decisions as using the full text while accounting for textual non-redundancy. To evaluate our method (DecSum), we build a testbed where the task is to summarize the first ten reviews of a restaurant in support of predicting its future rating on Yelp. DecSum substantially outperforms text-only summarization methods and model-based explanation methods in decision faithfulness and representativeness. We further demonstrate that DecSum is the only method that enables humans to outperform random chance in predicting which restaurant will be better rated in the future.
Academic neural models for coreference resolution (coref) are typically trained on a single dataset, OntoNotes, and model improvements are benchmarked on that same dataset. However, real-world applications of coref depend on the annotation guidelines
and the domain of the target dataset, which often differ from those of OntoNotes. We aim to quantify transferability of coref models based on the number of annotated documents available in the target dataset. We examine eleven target datasets and find that continued training is consistently effective and especially beneficial when there are few target documents. We establish new benchmarks across several datasets, including state-of-the-art results on PreCo.
In this paper, we present coreference resolution experiments with a newly created multilingual corpus CorefUD (Nedoluzhko et al.,2021). We focus on the following languages: Czech, Russian, Polish, German, Spanish, and Catalan. In addition to monoling
ual experiments, we combine the training data in multilingual experiments and train two joined models - for Slavic languages and for all the languages together. We rely on an end-to-end deep learning model that we slightly adapted for the CorefUD corpus. Our results show that we can profit from harmonized annotations, and using joined models helps significantly for the languages with smaller training data.
We offer an approach to explain Decision Tree (DT) predictions by addressing potential conflicts between aspects of these predictions and plausible expectations licensed by background information. We define four types of conflicts, operationalize the
ir identification, and specify explanatory schemas that address them. Our human evaluation focused on the effect of explanations on users' understanding of a DT's reasoning and their willingness to act on its predictions. The results show that (1) explanations that address potential conflicts are considered at least as good as baseline explanations that just follow a DT path; and (2) the conflict-based explanations are deemed especially valuable when users' expectations disagree with the DT's predictions.
We point out that common evaluation practices for cross-document coreference resolution have been unrealistically permissive in their assumed settings, yielding inflated results. We propose addressing this issue via two evaluation methodology princip
les. First, as in other tasks, models should be evaluated on predicted mentions rather than on gold mentions. Doing this raises a subtle issue regarding singleton coreference clusters, which we address by decoupling the evaluation of mention detection from that of coreference linking. Second, we argue that models should not exploit the synthetic topic structure of the standard ECB+ dataset, forcing models to confront the lexical ambiguity challenge, as intended by the dataset creators. We demonstrate empirically the drastic impact of our more realistic evaluation principles on a competitive model, yielding a score which is 33 F1 lower compared to evaluating by prior lenient practices.
Recent work on entity coreference resolution (CR) follows current trends in Deep Learning applied to embeddings and relatively simple task-related features. SOTA models do not make use of hierarchical representations of discourse structure. In this w
ork, we leverage automatically constructed discourse parse trees within a neural approach and demonstrate a significant improvement on two benchmark entity coreference-resolution datasets. We explore how the impact varies depending upon the type of mention.
