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Register a new userPrevalence of Parvovirus B19 in a group of thalassemia beta patients in Damascuse city
انتشار الفيروس الصغير B19 لدى مجموعة من مرضى التلاسيمية بيتا في مدينة دمشق
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Damascus University رسالة ماجستير
Publication date
2016
fields
Pharmacy
and research's language is
العربية
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Shamra Editor
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يعدي الفيروس الصغير B19 الأطفال والبالغين مسببا الحمامي العدوائية عند الأطفال والتهاب المفاصل عند البالغين ونوبات انعدان التنسج في النقي أو فقر الدم المزمن لدى المرضى الذين يعانون من الاضطرابات الدموية أو المناعية بالإضافة إلى موه الجنين او وفاته عند إصابة المرأة الحامل بهذا الفيروس
Parvovirus B19 infects children and adults , causing erythema infectiosum in children , polyarthritis in adults, aplastic crisis and chronic anemia in patients with hematological or immunological disorders, and fetal hydrops or fetal death .
References used
Heegaard ED. Brown KE. Human Parvovirus B19 Clin Microbial
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Parvovirus B19 infects children and
adults, causing erythema infectiosum (fifth disease),
polyarthritis, aplastic crisis and chronic anemia in patients with
hematological or immunological disorders, and fetal hydrops or
fetal death. This study ai
ms to estimate the prevalence of B19
IgM in Damascus patients with thalassemia major..
This study was conducted to determine the prevalence of hypogonadism among β-Thalassemia Major (β-TM) adolescent patients, and the role of iron chelation therapy (ICT) in its prevention. Data was collected from 60 β-TM patients and 35 controls aged 1
3─ 30 years through a questionnaire and a review of medical history to collect sociodemographic characteristics, transfusion regimen, chelating history and pubertal status. Complete blood count, serum ferritin, and pituitary-gonadal function tests were analyzed 1–2 weeks after blood transfusion. Logistic regression, independent t-test, and chi-square test were used to analyze our results and the significance was tested at p≤ 0.05. The overall prevalence of hypogonadism among β-TM patients was 75%, the mean of serum ferritin was 6704.83± 2849 ng/ml and all patients had serum ferritin above 2000 ng/ml indicating a severe iron overload. Low hemoglobin level (p=0.006), high ferritin level (p=0.018), high blood transfusion per year (24-blood transfusions) (p=0.007), and poor compliance to iron chelation therapy programs (p=0.001), were detected had significant partial effect in hypogonadism. In conclusion, hypogonadism is highly prevalent among Gaza strip β-TM patients. Its presence being associated with lower hemoglobin values, iron overload, high blood transfusion and low compliance of iron chelation therapy
113 psoriatic patients participated in the study. The patients were selected from the Dermatology and Venereology department at Alasad hospital in Lattakia city between 2012-2013 years. Mycological examination was carried out in all patients showing
psoriatic nail changes .The aim of the study is to evaluate : the frequency of nail changes in psoriatic patients, the frequency of onychomychosis in patients with nail psoriasis and the factors that may have a role in the incidence of onychomcosis in patients with nail psoriasis.
Nail changes were seen in (61.9%) of psoriatic patients (70 patients). Positive mycological cultures were obtained from 34 patients (48.6%). There was an increase of the incidence of onychomycosis in patients with high levels of NAPSI and long duration of psoriasis and nail psoriasis. There was a relationship between onychomycosis and the age of the patient. We found an increase of the incidence of onychomycosis among the patients who had a systemic therapy for psoriasis (methotrexate,cyclosporine) and the patients who had a history of contusion on nails. There was no relationship between onychomychosis and the gender of the patient.
This study confirmed that onychomycosis may occur in patients with nail psoriasis
Aims of study: 1-To determine the prevalence and 2- the pattern of hypodontia in
the permanent dentition in a sample of Syrian orthodontic patients who sought orthodontic
treatment.
Materials and Methods: The orthodontic records of 623 patients ag
ed 12 to 34, who
sought orthodontic treatment in the Department of Orthodontics, Dental faculty/Damascus
University, during the last three years (2011-2014), were investigated to establish the
prevalence of patients with one or more permanent missing teeth.
Results: 1-The prevalence of hypodontia was 7.10% of the studied sample (7.49% in
females, and 6.35% in males). Males were less affected than females with a ratio of 1:1.18
with no significant differences between genders (P = 0.063).
2-The most common missing tooth was maxillary lateral incisor (56.52%), the least
common missing tooth was maxillary first molar (0.87%). Missing in the maxillary jaw
was significantly more frequent than the mandible (P=0.041( with significantly more
anterior teeth missing than posterior teeth (P=0.009).
Conclusions: The prevalence of hypodontia showed in this study was within the
range published in the literature. The patterns are similar to most reported patterns in the
literature.
Background:Microscopic colitis (MC) encompasses collagenous and lymphocytic
colitis and is diagnosed by histopathological changes of random biopsies which tacken
from each segment of normal macroscopically colonic mucosae from patients who have
ch
ronic watery diarrhea of unknown etiology.
Aims:Prevalence of microscopic colitis in patients with chronic watery diarrhea and
have endoscopically normal colon .
Materials and Methods:We prospectively enrolled 84 patients reviewed in
ALASSAD and TISHREEN HOSPITALS between March 2015 until June 2016 .These
patients were having watery diarrhea more than 3 times a day for more 4 weeks. Atotal 84
patients were enrolled for a total colonoscopy until terminal ileum . Two biopsies were
obtained from all colonic segments and terminal ileum for diagnosed of microscopic
colitis. On histopathologic examination, criteria for lymphocytic colitis (intraepithelial
lymphocyte ≥ 20 per 100 surface epithelial cells, change in surface epithelium,
mononuclear infiltration of the lamina propria) and collagenous colitis (subepithelial
collagen band thickness ≥ 10 μm) were explored.
Results:Microscopic colitis was diagnosed in 33 (39%)patients {22lymphocytic
colitis,11collagenous colitis} . Female/Male: 15/18, mean age at diagnosis of microscopic
colitis : 37 year, range: 20-69, the median duration of diarrhea: 9.5 monthes , the median
number of bowel movements per day:5 times .And the common symptoms are:
abdominal pain and flatulence.
Conclusion :Biopsy of Syrian patients with the diagnosis of chronic watery diarrhea
of unknown etiology and normal colonoscopic findings will reveal microscopic colitis in
approximately 39% of the patients. Lymphocytic colitis is two times more frequent than
collagenous colitis in these patients.
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