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Application of Mie theory based electromagnetic scattering for differentiation between normal and cancerous cervical cells

تطبيق نظرية مي للتبعثر الكهرومغناطيسي للتمييز بين الخلايا السليمة و الخلايا السرطانية لأنسجة عنق الرحم

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 Publication date 2017
and research's language is العربية
 Created by Shamra Editor




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This paper presents the application of electromagnetic wave scattering in human cervical cells. Particularly, studying the effect of morphological and physiological alterations on the properties of light scattering. Tissue alterations are caused by multi-grade dysplastic cervical cells and its internal structures.



References used
WILSON R. H, CHANDRA M, SCHEIMAN J, SIMEONE D, MCKENNA B, PURDY J, and MYCEK M.A, 2009 - Optical spectroscopy detects histological hallmarks of pancreatic cancer, Optics Express 17,17502p
GREENING G, JAMES H, DIERKS M, VONGKITTIARGORN N, OSTERHOLM S, RAJARAM N. AND MULDOON T, 2016 - Towards monitoring dysplastic progression in the oral cavity using a hybrid fiber-bundle imaging and spectroscopy probe, Scientific Reports, 6p
BACKMAN V., GOPAL V., KALASHNIKOV M., BADIZADEGAN K., GURJAR R., WAX A., GEORGAKOUDI I., MEULLER M., BOONE C. W., et al., 2001 - Measuring cellular structure at sub micrometer scale with light scattering spectroscopy, IEEE Journal of Selected Topics in Quantum Electronics 7, 887p
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The research was conducted in the department of obstetrics and gynecology at Al-Assad university hospital in Lattakia in the period between (1/1/2014) – (30/6/2015). The study included (100) patient, who submitted to colposcopy and Papanicolaou smear to detect the effect of early marriage (early onset of sexual activity) on colposcopic and cellular finding in cervix . The results in (early married women) group (50) patient were compared to control group from patients who (not early married women)group (50) patient. We found that there was important difference in the rate of abnormal colposcopic findings : This rate in early married women was (26%) and in the second was (12%). We also found that there was important difference in the rate of abnormal cellular findings: This rate in early married women was (18%) and in the second was (8%). This assure the effect of early onset of sexual activity (early marriage) on colposcopical and cellular finding in cervix with assuring on the importance of frequent colposcopy and Papanicolaou smear test.
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Mankind is still suffering from many diseases , and with the development of civilization there are many diseases that appear with different clinical types , but tumors, especially malignant , are still very important. Cervical cancer is the secon d common cancer in women , as it is the cause of more than 200.000 deaths annually. Hence the importance of early detection of cervical cancer and of decreasing mortality.
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