لإنزيم الكاتلاز وظيقتين الأولى كتالازية تتخرب بارتفاع درجة الحرارة و الوظيفة الثانية أوكسيدية يزداد نشاطها بارتفاع درجة الحرارة.
يؤثر إنزيم الكاتالاز في مادة التفاعل أورثو - فينيلين ثنائي الأمين محولا إياها إلى مركبات آزو العطرية المسرطنة.
تثبط الحموض العضوية حمض البنزوئيك, حمض الساليسليك, و حمض الاسكوربيك فعل إنزيم الكاتالاز في مادة التفاعل أورثو - فينيلين ثنائي الأمين, و يكون التثبيط تنافسيا بوجود حمضي البنزوئيك و الساليسليك, بينما يكون التثبيط لا تنافسيا بوجود حمض الاسكوربيك.
Catalase enzyme has two functions, first is catalytic and
destroyed with high temperature.
The second function oxidic , increasing with high temperature.
The catalase enzyme effects on the substrate of ortho –
phenylene diamine turning it into aromatic cancerogenus azo
compounds
organic acids such as, benzoic acid, salicylic acid and ascorbic
acid inhibit the effect of catalase enzyme substrate ortho –
phenylene diamine. The inhibition is competitive when the
benzoic acid and salicylic acid effects , while the inhibition is
non competitive when the ascorbic acid effect.
References used
Seince E, F, and Knyazov P,.G , 1986-Molecular Oncologia. Leningrad,Medicine p.349
Kinzel ,V , Scribner J,.D , 1977- Cancer Experiments and Concepts . MIR, Moscow, p.360
Dixon, M, Webb, E .C. 1982- Enzymes . MIR , Moscow,p.1115
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