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Epidemiological Study of The Cutaneous Leishmaniasis Disease at Dermatological Hospital and General Clinic in Damascus

وبائية داء الليشمانية الجلدي لمراجعي مشفى الأمراض الجلدية و الزهرية والعيادات الشاملة في دمشق

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 Publication date 2003
  fields Biology
and research's language is العربية
 Created by Shamra Editor




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In this study the total of ٤١٥ cases of cutaneous leishmaniasis was evaluated from Dermatology hospital and General clinic in Damascus from February ٢٠٠١ to February ٢٠٠٢. Most of these cases was reported in Damascus and its suburb, and when we made the direct microscopic test, amastigotes were detectable in ٢٧١ cases, and the positive cases was increased to ٣٦٤ cases by realizing the parasite culture into diphasic N. N. N. media, which confirm the diagnosis.


Artificial intelligence review:
Research summary
تناولت هذه الدراسة وبائية داء الليشمانيا الجلدي في مشفى الجلدية والعيادات الشاملة بدمشق. تم تحليل 415 حالة من فبراير 2001 إلى فبراير 2002. أظهرت النتائج أن 90% من الحالات كانت في دمشق وريفها. عند الفحص المجهري المباشر، تم اكتشاف الطفيليات عديمة السوط في 271 حالة، وزاد العدد إلى 364 حالة عند إجراء الاستنبات على وسط N.N.N.، مما يؤكد أهمية استخدام كلا الاختبارين لتأكيد التشخيص. كانت نسبة الإصابة أعلى بين الذكور (62.41%) والفئة العمرية 16-40 سنة. معظم الآفات الجلدية كانت في المناطق المكشوفة من الجسم مثل الأطراف والوجه، وتنوعت الأشكال السريرية للآفة بين الدملي والقرحي والمقشر. الكلمات المفتاحية تشمل داء الليشمانيا الجلدي، الطور عديم السوط، الطور أمامي السوط، التشخيص، والاستنبات.
Critical review
دراسة نقدية: تعتبر هذه الدراسة مهمة لفهم وبائية داء الليشمانيا الجلدي في دمشق وريفها، ولكن هناك بعض النقاط التي يمكن تحسينها. أولاً، كان من الأفضل تضمين تحليل موسع للعوامل البيئية والاجتماعية التي قد تسهم في انتشار المرض. ثانياً، لم يتم توضيح مدى فعالية العلاجات المستخدمة أو تقديم توصيات واضحة للوقاية. أخيراً، كان من الممكن أن تكون الدراسة أكثر شمولاً إذا تم تضمين مناطق أخرى من سوريا لمقارنة النتائج وتقديم صورة أكثر شمولية عن انتشار المرض في البلاد.
Questions related to the research
  1. ما هي نسبة الإصابة بداء الليشمانيا الجلدي في دمشق وريفها؟

    بلغت نسبة الإصابة في دمشق وريفها 90% من الحالات المسجلة.

  2. ما هي الفئة العمرية الأكثر تعرضاً للإصابة بداء الليشمانيا الجلدي؟

    الفئة العمرية الأكثر تعرضاً للإصابة هي بين 16-40 سنة.

  3. ما هي أهمية استخدام كلا الاختبارين (الفحص المجهري المباشر والاستنبات) في تشخيص داء الليشمانيا الجلدي؟

    استخدام كلا الاختبارين ضروري لتأكيد التشخيص، حيث أن الفحص المجهري المباشر كشف الطفيليات في 271 حالة، بينما زاد العدد إلى 364 حالة عند إجراء الاستنبات.

  4. ما هي الأشكال السريرية للآفات الجلدية التي تم ملاحظتها في الدراسة؟

    الأشكال السريرية للآفات الجلدية تنوعت بين الدملي، الدملي الجاف، الدملي المقشر، القرحي، القرحي المقشر، وفي بعض الحالات وذمي مقشر.


References used
Knio K.N., Baydoun E., Taw R. R., Nuwayri-Salti N.. Isoenzyme characterization of Leishmania isolates from Lebanon and Syria.2000
Rioux J. A., Ashford R. W., Khiam i A. Ecoepidemiology of leishmaniasis in Syria. ٣. Leishmania major infection in Psammomys obesus provides clues to life history of rodent and possible control measures.1992
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Through this research, case studies were reviewed which reviewed the dermatology department at Tishreen University Hospital in Lattakia and specialized centers for leishmaniasis and parasitic diseases in Lattakia and Tartous governorates from the beg inning of April 2018 until the end of December 2019. Where Syria is one of the areas endemic with cutaneous leishmaniasis, as we have noticed in recent years the number of skin infections has increased dramatically in all Syrian governorates, which has made leishmaniasis an important health problem that warrants study. In order to isolate and determine the type and strains of the parasite responsible for skin injuries in Syria, in order to develop a plan to combat this disease and limit its spread. Microscopy and transplantation methods are the gold standard for diagnosing cutaneous leishmaniasis, especially in poor areas where this disease is common. Through this study it was found that the age group most exposed to infection is between 16 - 40 years and that the highest incidence was among males. As for the distribution of skin lesions, the highest percentage was recorded on the face, upper and lower extremities.
Background& Objective: Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and non-dermatophyte molds. Far more than being a simple cosmetic problem, infected nail serves as a chronic reservoir, which can give rise to repeated mycotic infections. This study aim to identify the common fungal species which are responsible for onychomycosis in clinically suspected patients of onychomycosis in Dermatology and Venereal Diseases Hospital in Damascus between October 2010 and July 2011. Materials & Methods: Both direct microscopy and culture of the nail material were performed to identify the causative fungi of onychomycosis. Results: Culture positivity was obtained in 65 of the 76 clinically suspected samples, etiological fungal agents were (%61.5) dermatophytes, (24.6%) yeasts, and (13.9 %) non-dermatophyte molds . The isolated fungal species were (43.1%) Trichophyton Rubrum and (16.9%) T. Interdigitale (1.5%) T.Verrucosum Aspergillus Versicolor which was the most frequent non dermatophyte molds. Females were affected in fingernails more frequently than males, while males were affected in toenails more frequently than females, and in both sexes those most infected were between 20-40 years of age. Conclusion: Dermatophytes, in particular T. rubrum, but also T. Interdigitale, are the most frequently isolated causative agents in onychomycosis in patients seen in Dermatology and Venereal Diseases Hospital in Damascus . In addition, yeasts may be isolated relatively frequently, while molds are uncommon.
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