Subscribe to the gold package and get unlimited access to Shamra Academy
Register a new userDetermination of Tropicamed by Kinetic Spectrophotometric Method in Pharmaceutical Preparations
تحديد التروبيكاميد بالطريقة الطيفية الضوئية الحركية في المستحضرات الصيدلانية
1294
0 25
0
(
0
)
Created by
Shamra Editor
Ask ChatGPT about the research
اقترحت طريقة طيفية حركية جديدة لتحديد التروبيكاميد (TPC) في الحالة النقية و في المستحضرات الصيدلانية. اعتمدت الطريقة على أكسدة (TPC) بواسطة برمنغنات البوتاسيوم في وسط قلوي قوي من هيدروكسيد الصوديوم عند القيمة (pH=12), لتشكيل ناتج تفاعل أخضر اللون يملك قمة امتصاص عظمى عند nm610 عند درجة الحرارة 25±0.5 ºC.
A new, simple and sensitive kinetic spectrophotometric method has been proposed for the determination of tropicamed (TPC) in pure and pharmaceutical formulations. The method is based on oxidation TPC by potassium permanganate in strong alkaline medium (pH=12) to form green colored product with absorbance maximum at 610nm.
References used
Hardman J. G., Limbird L. E., Molinoff P. B., Ruddon R. W., 1996- The Pharmacological Basis of Therapeutics, Goodman and Gilman's, 9th edition, Mc Graw-Hill, New York, 156- 7,1635
Hardman J. G., Goodman Gilman A., Limbird L. E., 2001- The pharmacological pasis of therapeutics, 10th ed. New York: Mc Graw-Hill, 1673-1685
Delgabo J. N., Remers (editors.), W. A., 2004- Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry, 10th ed. New York: Lippincott-Raven Publ, 585
rate research
Read More
Simple, accurate and reliable spectrophotometric method
has been developed for the quantitative determination of
Cephalosporins: Cefaclor, Cefalexin, Cefadroxil in pure and
pharmaceutical formulations. The method is based on the
determination of that in aqueous medium pH=6.45 at
25±0.5ºC.
New, accurate, sensitive and reliable kinetic spectrophotometric
method for the assay of fluvastatin sodium (FVS) in pure form and
capsules has been developed. The method involves the oxidative
coupling reaction of FVS with 3-methyl-2-benzothiazolinone hydrazone
hydrochloride monohydrate (MBTH) in the presence of Ce(IV) in an
acidic medium to form colored product with lambdamax at 615 nm.
A Simple, accurate and highly sensitive spectrophotometric method have been
developed for the rapid determination of Ofloxacine (OFX) in pure form and
pharmaceutical formulations. The visible spectrophotometric method was based on the
formation of
a Orange Yellow colored complex between the (OFX) and 2-amino-6-
nitrobenzothiazole (ANB) at pH 5.2 and 80±5 ºC in 5 min., and λmax at 440 nm. The
effects of analytical parameters on the reported system were investigated. Beer's law was
obeyed in the concentration range of 1.80-86.72 μg/mL, with a percentage relative standard
deviation not exceed ±2.54 and the molar absorptivity coefficients was 3.952×103
(L/mol.cm). Interferences of the other ingredients and excipients were not observed, the
results showed that the developed method with the accuracy and sensitivity highs.
A sensitive, simple and selective spectrofluorimetric method
has been proposed for determination Captopril (CPT) in pure form
and pharmaceutical preparations. This method depends on the
formation of complex between Captopril and Copper (II) at
pH=3.5.
A sensitive, simple, selective spectrophotometric method has been developed for determination Cobalt (II) with 1-(2-pyridylazo)-2 naphthol (PAN). This method ralies on the formation of stable red colored complex at pH=4.1 which has an absorption maximum at 580nm.
Log in to be able to interact and post comments
comments
Fetching comments
Sign in to be able to follow your search criteria
