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Register a new userDetermination of Captopril in Pharmaceutical Formulations Using Spectrofluorimetric Method
تحديد الكابتوبريل في المستحضرات الصيدلانية باستخدام طريقة الفلورة الجزيئية
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اقترحت طريقة طيفية تفلورية حساسة و بسيطة لتحديد الكابتوبريل (CPT) في الحالة النقية و في المستحضرات الصيدلانية. اعتمدت الطريقة على تشكيل معقد بين الكابتوبريل و أيونات النحاس عند قيمة pH=3.5.
A sensitive, simple and selective spectrofluorimetric method has been proposed for determination Captopril (CPT) in pure form and pharmaceutical preparations. This method depends on the formation of complex between Captopril and Copper (II) at pH=3.5.
References used
PARFITT K., 1999- Martindale: The Complete Drug Reference, The Pharmaceutical Press (Ph P), 720, 836
CUSHMAN D. W., CHEUNG H. S., SABO E. F., ONDETTI M. A., 1977- Design of Potent Competitive Inhibitors of Angiotensin-Converting Enzyme. Carboxyalkanoyl and Mercaptoalkanoyl Amino Acids, Biochemistry, 16, 5484- 5491
ANTAKLI S., SARKIS N., KABAWEH M., 2010- Determination of Captopril Drug by Application of 1,10- Phenanthroline in the Spectrophotometric Technique, Asian Journal of Chemistry, 22(6), 4931-3938
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