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OFF pump coronary artery by- pass- Why? History and the benefiles

القلب النابض في المجازات الاكليلية لماذا؟ تاريخيا و فوائد الاستخدام

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 Publication date 2016
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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OFF pump coronary artery by pass surgery when It is done by experienced surgeons and with new cardiac stabilizer which allows to perform a complete revascularization with a good results. In additionally OFF PUMP decrease the morbidity coronary artery by pass such as stroke , renal failure and need for blood transfuration.

References used
Diegeler ,A, Doll , N , Rauch , T, et al humoral immune response during coronary bypass grafiting : a comparison of limited approach off-pump technique, and conventional cardiopulmonary bypass. Circulation 2000 ; 102 : Suppl 3 : 111 – 95
Puskas , JD, William, WH, Mahoney, EM, et al OFF-PUMP vs .conventional coronary artery bypass grafting: early and 1-year grft patency, cost, and quality – of- life outcomes: a randomized trial. JAMA 2004 ; 291 : 1841 – 1849
Houlind, K, Kjeldsen, BJ, Madsen ,SN, et al ON-PUMP versus OFF-PUMP coronary artery bypass surgery in elderly patients: resultsfrom the Danish on-pumpversus OFF-PUMP randomization study. Circulation 2012; 125: 2431- 2439
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Protection against cardiac ischemia/reperfusion injury is the basic objective in open heart surgery, and it may be achieved by pharmacological preconditioning or Postconditioning. In this study, we aimed to compare the effects of two different anest hetic techniques (inhalation and total intravenous anesthesia) on ischemia-reperfusion injury in Coronary Artery Bypass Graft surgery. 80 CABG patients were randomly assigned into one of tow groups: Group A Sevoflurane (n=40) and Group B total intravenous anesthesia (n=40) with Propofol . data of hemodynamic monitoring and inotrops using were recorded. Arterial blood samples were taken in the preoperative period (T0), 12th hours (T1) ,24th hours (T2) and 48th hours postoperatively, and Troponine I levels were measured . The time of ventilation, ICU and total hospitalization were recorded . Postoperative levels of troponine I were significantly lower in the Sevoflurane group with less using of inotrops and less staying in the ICU post-op . We conclude that the use of a volatile anesthetic regimen in CABG surgery associate with better preservation of myocardial function and a reduced postoperative release of troponine I.
This study was carried out in AL-ASSAD and Tishreen University Hospitals during the years 2013-2015, and included 174 patients who have been treated. Male: Female ratio was 1:2, and the average age of the sample of patients was 63. Great saphenous vein (medial) and internal thoracic artery Were used as grafts. analyzes blood values were normal in all patients before surgery. after surgery it has never been transfer platelets in the case of the beating heart .In the open-heart the average transfer platelet in patients was (0.23), the average amount of bleeding into Drainage in the beating heart surgeries was (902 ml) and was in the open-heart (1279 ml), the number of patients bled and the chest was opened again because of bleeding was (14 patients) it is (8%) of total patients , prolonged ACT was the most important cause of the bleeding with rate (64.2%), the percentage of patients who had Tamponade was (42.8%), the using of CPB more than 100 minutes has the greatest impact of bleeding with rate (78.5) .
Heart disease, particularly coronary artery disease is a major cause of morbidity and mortality among patients with diabetes mellitus . In addition to the increased clinical incidence of coronary artery disease , the extent of coronary arteries st enosed is also greater among diabetics . T his study showes that diabetics, compared to non-diabetics ,have a higher incidence of multiple vessel disease (٨٤٪ vs ٤٨٪) and lower incidence of one vessel disease . It also showes that left ventricular function and left ventricular wall movement are more impaired in diabetics .
Spontaneous coronary artery dissection (SCAD) is an infrequent and often missed diagnosis among patients presenting with acute coronary syndrome (ACS). Unfortunately, SCAD can result in significant morbidities such as myocardial ischemia and infarcti on, ventricular arrhythmias and sudden cardiac death. Lack of angiographic recognition from clinicians is a major factor of under-diagnosis. With the advent of new imaging modalities, particularly with intracoronary imaging, there has been improved diagnosis of SCAD. The aim of this paper is to review the epidemiology, etiology, presentation, diagnosis and management of SCAD.
Machine learning solutions are often criticized for the lack of explanation of their successes and failures. Understanding which instances are misclassified and why is essential to improve the learning process. This work helps to fill this gap by pro posing a methodology to characterize, quantify and measure the impact of hard instances in the task of polarity classification of movie reviews. We characterize such instances into two categories: neutrality, where the text does not convey a clear polarity, and discrepancy, where the polarity of the text is the opposite of its true rating. We quantify the number of hard instances in polarity classification of movie reviews and provide empirical evidence about the need to pay attention to such problematic instances, as they are much harder to classify, for both machine and human classifiers. To the best of our knowledge, this is the first systematic analysis of the impact of hard instances in polarity detection from well-formed textual reviews.

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