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Register a new userKikuchi’s Disease: A Case Report and Review of the Literature
داء كيكوشي: عرض حالة سريرية و مراجعة في الأدب الطبي
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محمود باكير( باحث )
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داء كيكوشي و يدعى أيضاً داء كيكوشي- فوجيموتو، أو التهاب العقـد اللمفاويـة المنخـر مرض نادر الحدوث، و مجهول السبب، و محدد لنفسه. وردت أول التقارير في الأدب الطبـي عن هذا المرض من اليابان عام 1972 و بشكل منفصل من قبل طبيبـين همـا كيكوشـي و فوجيموتو. و تبعتها تقارير لحالات مشابهة من مناطق أخرى في العالم. سجلنا تقريـرا لأول حالة بداء كيكوشي- فوجيموتو في سورية بمشفى المواساة الجامعي، عند رجل بعمـر 38 سنة، و قد تظاهر المرض بحرارة مزمنة مجهولة السبب منذ أكثر من شهرين مع ضخامات عقد لمفاوية متعددة. قمنا بمراجعة الأدب الطبـي و تلخـيص أهـم الخـصائص الـسريرية و الموجودات المخبرية و النسيجية المميزة لداء كيكوشي- فوجيموتو.
Kikuchi’s disease called also Kikuchi- Fujimoto’s disease or Histiocytic necrotizing lymphadenitis is a rare entity. It is a self-limiting process of unknown etiology first reported in Japanese literature separately by Kikuchi and Fujimoto in 1972. Then similar cases have subsequently been reported throughout the world. We reported a case of Kikuchi's disease in a. 38-year-old man presenting with generalized lymphadenopathy and persistent fever throughout more than 2 months. It’s the first case was diagnosed in Al muwasat University Hospital in Syria. We reviewed the literature to summarize and report the most common clinical, laboratory and histology characteristics of Kikuchi- Fujimoto’s disease.
References used
Dorfman RF: Histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto. Arch Pathol Lab Med 111:1026-1029, 1987
Pileri S, Kikuchi M, Helbron D, et al: Histiocytic necrotizing lymphadenitis without granulocytic infiltration. Virchows Archives (A) Pathol Anat Histol 395:257-271, 1982
Al-Nazer MA; Al-Hadad AM; Al-Aithan SA; Al-Salem AH; Al-Faraj AA; Al-Saeed HH:Kukuchi-Fujimito disease.Saudi Med J 2002 Apr;23 (4):405
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