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Automated Diagnosis Of Cutaneous Malignant Melanoma in Histological Slides Using Spectral Imaging Technology

التشخيص المؤتمت للملانوم الجلدي عن طريق تصوير الشرائح النسيجية الطيفي

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 Publication date 2015
and research's language is العربية
 Created by Shamra Editor




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Inasmuch as for incrimination of occurrence dermal malignant melanoma and difficulties of the clinical and histological diagnosis, so it is needed to search about method, giving fast diagnosis and self of high credibility, so the automatic spectral imaging was for the histological slides of dermal melanoma, where use of the morphological information is complete with the local information in establishing of the tissue print, through education of the machine (machine learning). 31 Cutaneous biopsies have been studied, of their 11 malignant melanomas, 16 benign lesions, and 4 normal skin. It has done spectral imaging for Histological sections stained routinely during the evaluation in digital camera pick up (CCD Camera) on luminous spectroscope, his luminous wavelengths ranges from 390-700 nanometer. the automated classifying results showed in the acquaintance on the malignant cells in tumor tissues in a ratio of ranged between 65-82%, these are very promising results. method of the non-supported classification revealed better results. in the future, we must complete classification of all types of other tissues, and build data base characterized each type of disease in various tissues. in order to use it as supportive factor in the accurate diagnosis and correct.


Artificial intelligence review:
Research summary
تناولت هذه الدراسة التشخيص المؤتمت للملانوم الجلدي باستخدام تقنية التصوير الطيفي للشرائح النسيجية. نظراً لتزايد حدوث الملانوم الجلدي وصعوبات التشخيص السريرية والنسجية، تم استخدام التصوير الطيفي المؤتمت كطريقة سريعة وذات مصداقية عالية. تم دراسة 31 خزعة جلدية، منها 11 ملانوم خبيث، و16 آفة حميدة، و4 خزعات لجلد طبيعي. استخدمت كاميرا رقمية مركبة على مطياف ضوئي لالتقاط الصور، وطبقت خوارزميات التصنيف الموجه وغير الموجه لتحليل البيانات. أظهرت النتائج أن نسبة التعرف على الخلايا الخبيثة تراوحت بين 65-82%، وكانت النتائج واعدة جداً. أوصت الدراسة بضرورة استكمال تصنيف أنواع أخرى من الأنسجة وتشكيل قاعدة بيانات لكل نوع لدعم التشخيص الدقيق.
Critical review
دراسة نقدية: على الرغم من أن الدراسة قدمت نتائج واعدة في مجال التشخيص المؤتمت للملانوم الجلدي، إلا أن هناك بعض النقاط التي تحتاج إلى مزيد من البحث والتطوير. أولاً، العينة المدروسة صغيرة نسبياً، مما قد يؤثر على دقة النتائج. ثانياً، لم يتم مناقشة تأثير العوامل البيئية والوراثية على دقة التشخيص المؤتمت. ثالثاً، يجب تحسين الخوارزميات المستخدمة لتقليل نسبة الخطأ وزيادة الدقة. وأخيراً، يجب إجراء دراسات مقارنة مع طرق التشخيص التقليدية لتحديد مدى فعالية التقنية الجديدة.
Questions related to the research
  1. ما هي نسبة التعرف على الخلايا الخبيثة باستخدام التصوير الطيفي المؤتمت؟

    تراوحت نسبة التعرف على الخلايا الخبيثة بين 65-82%.

  2. كم عدد الخزعات الجلدية التي تم دراستها في هذه البحث؟

    تم دراسة 31 خزعة جلدية.

  3. ما هي الخوارزميات المستخدمة في التصنيف في هذه الدراسة؟

    تم استخدام خوارزميات التصنيف الموجه وغير الموجه.

  4. ما هي التوصيات المستقبلية التي قدمتها الدراسة؟

    أوصت الدراسة بضرورة استكمال تصنيف أنواع أخرى من الأنسجة وتشكيل قاعدة بيانات لكل نوع لدعم التشخيص الدقيق.


References used
ROSAI, J. Rosai and Ackerman's Surgical Pathology. 8th ed., Mosby, USA & London, 2004, 2977
RUBIN, E. Essential Pathology. 3rd ed., Lippincott Williams& Wilkins, USA, London, & Tokyo, 2001, 786
DE VRIES, E. S. ; VISSER, L. V. RISING Trends In The Incidence And Mortality From Cutaneous Melanoma In The Netherland, A Northwest Gradient. EurJ Cancer, 39, 1439-1446, 2003
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