Do you want to publish a course? Click here

Automated Diagnosis Of Cutaneous Malignant Melanoma in Histological Slides Using Spectral Imaging Technology

التشخيص المؤتمت للملانوم الجلدي عن طريق تصوير الشرائح النسيجية الطيفي

881   0   109   0 ( 0 )
 Publication date 2015
and research's language is العربية
 Created by Shamra Editor




Ask ChatGPT about the research

Inasmuch as for incrimination of occurrence dermal malignant melanoma and difficulties of the clinical and histological diagnosis, so it is needed to search about method, giving fast diagnosis and self of high credibility, so the automatic spectral imaging was for the histological slides of dermal melanoma, where use of the morphological information is complete with the local information in establishing of the tissue print, through education of the machine (machine learning). 31 Cutaneous biopsies have been studied, of their 11 malignant melanomas, 16 benign lesions, and 4 normal skin. It has done spectral imaging for Histological sections stained routinely during the evaluation in digital camera pick up (CCD Camera) on luminous spectroscope, his luminous wavelengths ranges from 390-700 nanometer. the automated classifying results showed in the acquaintance on the malignant cells in tumor tissues in a ratio of ranged between 65-82%, these are very promising results. method of the non-supported classification revealed better results. in the future, we must complete classification of all types of other tissues, and build data base characterized each type of disease in various tissues. in order to use it as supportive factor in the accurate diagnosis and correct.


Artificial intelligence review:
Research summary
تناولت هذه الدراسة التشخيص المؤتمت للملانوم الجلدي باستخدام تقنية التصوير الطيفي للشرائح النسيجية. نظراً لتزايد حدوث الملانوم الجلدي وصعوبات التشخيص السريرية والنسجية، تم استخدام التصوير الطيفي المؤتمت كطريقة سريعة وذات مصداقية عالية. تم دراسة 31 خزعة جلدية، منها 11 ملانوم خبيث، و16 آفة حميدة، و4 خزعات لجلد طبيعي. استخدمت كاميرا رقمية مركبة على مطياف ضوئي لالتقاط الصور، وطبقت خوارزميات التصنيف الموجه وغير الموجه لتحليل البيانات. أظهرت النتائج أن نسبة التعرف على الخلايا الخبيثة تراوحت بين 65-82%، وكانت النتائج واعدة جداً. أوصت الدراسة بضرورة استكمال تصنيف أنواع أخرى من الأنسجة وتشكيل قاعدة بيانات لكل نوع لدعم التشخيص الدقيق.
Critical review
دراسة نقدية: على الرغم من أن الدراسة قدمت نتائج واعدة في مجال التشخيص المؤتمت للملانوم الجلدي، إلا أن هناك بعض النقاط التي تحتاج إلى مزيد من البحث والتطوير. أولاً، العينة المدروسة صغيرة نسبياً، مما قد يؤثر على دقة النتائج. ثانياً، لم يتم مناقشة تأثير العوامل البيئية والوراثية على دقة التشخيص المؤتمت. ثالثاً، يجب تحسين الخوارزميات المستخدمة لتقليل نسبة الخطأ وزيادة الدقة. وأخيراً، يجب إجراء دراسات مقارنة مع طرق التشخيص التقليدية لتحديد مدى فعالية التقنية الجديدة.
Questions related to the research
  1. ما هي نسبة التعرف على الخلايا الخبيثة باستخدام التصوير الطيفي المؤتمت؟

    تراوحت نسبة التعرف على الخلايا الخبيثة بين 65-82%.

  2. كم عدد الخزعات الجلدية التي تم دراستها في هذه البحث؟

    تم دراسة 31 خزعة جلدية.

  3. ما هي الخوارزميات المستخدمة في التصنيف في هذه الدراسة؟

    تم استخدام خوارزميات التصنيف الموجه وغير الموجه.

  4. ما هي التوصيات المستقبلية التي قدمتها الدراسة؟

    أوصت الدراسة بضرورة استكمال تصنيف أنواع أخرى من الأنسجة وتشكيل قاعدة بيانات لكل نوع لدعم التشخيص الدقيق.


References used
ROSAI, J. Rosai and Ackerman's Surgical Pathology. 8th ed., Mosby, USA & London, 2004, 2977
RUBIN, E. Essential Pathology. 3rd ed., Lippincott Williams& Wilkins, USA, London, & Tokyo, 2001, 786
DE VRIES, E. S. ; VISSER, L. V. RISING Trends In The Incidence And Mortality From Cutaneous Melanoma In The Netherland, A Northwest Gradient. EurJ Cancer, 39, 1439-1446, 2003
rate research

Read More

Malignancy is the second most common reason of death in most countries. Diagnosis of thyroid cancers is one of the most difficult medical problems. Therefore, it important to use diagnosing methods that bring about quick results, are less costly, and prevent errors based on personal factors. An example of such new methods is the use of automated spectral imaging, which gives more information about the structure of tissue, through the formation of fingerprint histological diagnosis used in the automated machine. This study included 25 cancer cases and 26 specimens of non-malignant thyroid or normal. The credibility of method is reflected in the high rates of correct diagnosis in cancer samples (TP) = 92% and the negative result in sections of non-malignant (FN) = 96%. This method represents the use of automation technologies and artificial intelligence to facilitate and speed up the diagnosis of cancers and can be used to diagnose other organs and other tissues.
According to the high specificity and sensitivity of ELISA test, we tried in this preliminary study, to certify the usefulness of ELISA test in the detection of specific antibodies (IgG) to cutaneous leishmaniasis(CL) in SYRIA, in order to certify the diagnosis of this disease by using the classic methods (observation microscopic – culture).
Cutaneous leishmaniasis is still one of the most important health problems in Syria which witnessed increasing the numbers of cutnaneous leishmaniasis reported, especially during the crisis ,Also the direct microscopic examination of Giemsa-stained scrapings of lesions is still a suitable method for diagnosis of cutaneous leishmaniasis due to the low cost, ease of performance, speed, and lack of a need for sophisticated laboratory equipment.
The aim of this experiment was to study Histological changes associated with different stages of infection with hepatic coccidiosis induced by Eimeria stiedae in rabbits.
Through this research, case studies were reviewed which reviewed the dermatology department at Tishreen University Hospital in Lattakia and specialized centers for leishmaniasis and parasitic diseases in Lattakia and Tartous governorates from the beg inning of April 2018 until the end of December 2019. Where Syria is one of the areas endemic with cutaneous leishmaniasis, as we have noticed in recent years the number of skin infections has increased dramatically in all Syrian governorates, which has made leishmaniasis an important health problem that warrants study. In order to isolate and determine the type and strains of the parasite responsible for skin injuries in Syria, in order to develop a plan to combat this disease and limit its spread. Microscopy and transplantation methods are the gold standard for diagnosing cutaneous leishmaniasis, especially in poor areas where this disease is common. Through this study it was found that the age group most exposed to infection is between 16 - 40 years and that the highest incidence was among males. As for the distribution of skin lesions, the highest percentage was recorded on the face, upper and lower extremities.
comments
Fetching comments Fetching comments
Sign in to be able to follow your search criteria
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا