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Register a new userBone involvement in systemic mastocytosis
الإصابة العظمية في كثرة الخلايا البدينة الجهازية من حالة سريرية إلى مراجعة أدبية
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Aِl-Baath University ورقة بحثية
Publication date
2014
fields
Medicine
and research's language is
العربية
Authors
غازي قاسة( باحث )
Created by
Shamra Editor
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تعتبر كثرة الخلايا البدينة الجيازية من الأورام الخبيثة النادرة و ربما تسبب إصابات عظمية. ترقق العظام الثانوي يكون الأكثر شيوعاً و ربما يسبب كسور فقرية بشكل خاص. نحن سجلنا هنا حالة مريضة عمرها 53 سنة مصابة ب 3 كسورر قطنية غير رضية , و شخص لهاكثرة الخلايا البدينة الجهازية.بعد كتابة أنماط الإصابة العظمية و الفيزولوجيا المرضية قمنا بتلخيص طرق التشخيص و طرق التقيّيم الخاصة بالاعتماد على المراجعة الأدبية .
Systemic mastocytosis (SM) is a rare malignant neoplasia, which can create bone complications. The most frequent of those is secondary osteoporosis, sometimes responsible for fractures, especially of the rachis. We report the case of a 53 year-old woman with 3 non-traumatic lombar fractures, leading to the diagnosis of SM, after bone marrow trephine biopsy. We describe the different types of bone involvement in MS, their physiopathology, their diagnosis and treatment, with help of a bibliographic review.
References used
Karine B, Atteintes osseuses des mastocytoses systématiques, Revue du rhumatisme monographies 80 (2013) 120-124
Travis WD, Li CY, Bergstralh EJ, Yam LT, Swee RG. Systemic mast cell disease: analysis of 58 cases and literature review. Medicine. 1988;67:345–68
Chiappetta N, Gruber B. The role of mast cells in osteoporosis.Semin Arthritis Rheum. 2006 Aug;36(1):32–6
Tharp MD. Southwestern Internal Medicine Conference: the spectrum of mastocytosis. Am J Med Sci. 1985;289:119–32
Suzuki K, Lees M, Newlands GF, Nagase H, Woolley DE. Activation of precursors for matrix metalloproteinases 1 (interstitial collagenase) and 3 (stromelysin) by rat mast-cell proteinases I and II. Biochem J. 1995 Jan 1;305(Pt 1):301–6
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