Introduction 7 Visceral Leishmaniasis( VL )is characterized by a spectrum of
clinical features, with high cure rates in early diagnosis.
Objective: the objective is to describe the clinical and epidemiological features and
laboratory variables of
children with visceral leishmaniasis ,And to define the importance
of a positive direct investigation of the parasite in Bone marrow in the diagnosis of disease
.
Patients and Methods : It was a case series study of )52( cases of Visceral
Leishmaniasis which were hospitalized between June-20 31and June-2014 in Al -Assad
University Hospital ,Latakia
Results 52 7 7 children were included in this study .Majority of the patients (92%)
presented with fever ,common findings in physical examination were(100%) Pallor and
(97%) splenomegaly
The direct investigation of parasite in Bone marrow was positive in )%55( of cases .
Visceral Leishmaniasis is still seen in developing country
To study the epidemiology of Visceral Leishmaniasis cases
hospitalized in Damascus University Children Hospital.
It was retro-spective study on (89) cases of Visceral
Leishmaniasis hospitalized between 1993 and 2005.
In the present study, we tried to compare the sensitivity and the specificity
of the rK39 strips and DAT, to serodiagnose the visceral leishmaniasis disease
in some endemic villages in south of Syria, in order to apply the best and the
easy test i
n the epidemiological studies, for serodiagnosis this disease not only in
symptomatic patients but also in asymptomatic and suspected cases in order to
treat them early and rapidly.
Patients infected with different species of Leishmania in Syria develop
specific antibodies. For this reason, we have developed an immunodot assay for
the serodiagnosis of cutaneous and visceral leishmaniasis, which utilizes antihuman
IgG conjugat
ed with peroxidase (HRP) as the visualizing agent.
