Aim of study: Comparing the efficacy of combination (Midazolam – Hydroxyzine)
with and without nitrous oxide and oxygen in sedating uncooperating school children
undergoing dental treatment.
Materials and Methods: This was a prospective, triple bl
ind, randomized, cross
over, clinical study of uncooperative school children in need of two sessions of Bilateral
mandibular dental treatment. 30 children ages (6-9) years, were randomly selected to
receive one of two regimens: Regimen (A) contain oral midazolam (M) 7.5 mg and
hydroxyzine (H) 10 mg with oxygen (O2) 100%, while Regimen (B) contain oral
midazolam (M) 7.5 mg and hydroxyzine (H) 10 mg with nitrous oxide\oxygen (N2O\O2)
50% . And in the second session, the other regimen was administered. the behavior was
assessed using modified Houpt rating scale by reviewing the records of patients in
pretreatment stage ( injection, rapper dam, operating dental drill without touching the tooth
then with touching it) and during treatment stages ( drilling, restoration ). Beside recording
the vital signs.
Results: Comparing the overall assessment of the two regimens the success rate was
(86.67%) in regimen (A) and (93.34%) in regimen (B). No significant statistical difference
existed between the two regimes. The vital signs remained within normal limits in all cases
and no series side effects appeared.
The aims of this study by sample of dentists to identify the
percentage were used of some common topical anesthetics and
the sedation in their practice and to know if there is a influence of
specialize in OMFS in the results.
Background & Objective: IV sedation has become established as an alternative to general anesthesia in dental treatment of patients with intellectual disability.
AIM: This study was designed to evaluate analgesic efficacy and clinical safety of intra
venous propofol sedation for handicapped, and determine the effect of gender, age, time of treatment on the recovery time for the patient.
Methods & Materials: Twenty eight handicapped patients with cerebral palsy, intellectual disability, Down syndrome, classified as ASA 1(15 males, 13 females) in the age-group of 3-34 years, and in the weight group of 10-60 kg were selected, Who had undergone deep intravenous sedation using a mean dose
of 2.5 mg/kg as only one dose before treatment. The handicapped were treated at maxillio-facial hospital
at Faculty of dentistry - Damascus University in the hospital setting then in the recovery room were observed for vital signs.
Results: IV sedation with propofol was effective for dental treatment in all cases. The dental proucedures were: extraction, ART, and scaling. The mean treatment time was 21 minutes. There was no significant effect for recovery time (p<0.05) with gender, age, weight of the patient and the time of treatment.
Conclusions: The results of this study showed that intravenous propofol sedation appears to be a safe and effective method for dental treatment of handicapped patients, when administered and monitored by a qualified anesthetist, offering the practitioner an alternative to general anesthesia.
