The aims of this study by sample of dentists to identify the
percentage were used of some common topical anesthetics and
the sedation in their practice and to know if there is a influence of
specialize in OMFS in the results.
Aim of study: Comparing the efficacy of combination (Midazolam – Hydroxyzine)
with and without nitrous oxide and oxygen in sedating uncooperating school children
undergoing dental treatment.
Materials and Methods: This was a prospective, triple bl
ind, randomized, cross
over, clinical study of uncooperative school children in need of two sessions of Bilateral
mandibular dental treatment. 30 children ages (6-9) years, were randomly selected to
receive one of two regimens: Regimen (A) contain oral midazolam (M) 7.5 mg and
hydroxyzine (H) 10 mg with oxygen (O2) 100%, while Regimen (B) contain oral
midazolam (M) 7.5 mg and hydroxyzine (H) 10 mg with nitrous oxide\oxygen (N2O\O2)
50% . And in the second session, the other regimen was administered. the behavior was
assessed using modified Houpt rating scale by reviewing the records of patients in
pretreatment stage ( injection, rapper dam, operating dental drill without touching the tooth
then with touching it) and during treatment stages ( drilling, restoration ). Beside recording
the vital signs.
Results: Comparing the overall assessment of the two regimens the success rate was
(86.67%) in regimen (A) and (93.34%) in regimen (B). No significant statistical difference
existed between the two regimes. The vital signs remained within normal limits in all cases
and no series side effects appeared.
