We retrospectively reviewed data of all patients who underwent study or surgery for Lung Cancer from (1997 to 2012) in the department of thoracic surgery at Alassad University Hospital in Damascus. There were 2029 patients with Lung cancer,1727 male
85,11% and 302 female 14,88%,87,53% of patients were smoking, and cough was the most common symptom about 70% of patients. There were 889 squamous cell carcinoma 43,81%, 702 adenocarcinoma 34,79%, 246 small cell carcinoma 12,12%,67 large cell carcinoma 3,3% and 66 carcinoid tumor 3,25%; the staging was 6,35% stageI,14,98% stageII,15,91% stage IIIA,29,02% stageIIIB,33,71% stage IV. Radical Surgery consisted of 621 formal lung resection 229 lobectomies 36,87%, 163 bilobectomies 26,2%, 158 pneumonectomy 25,44%,35 sleeve or bronchoplastic resection 5,63% ,36 partial resection 6,15%. The perioperative mortality was 3,05% and the overall 5 year survival was 22,9%. Our study resembles most of the studies made in the developing countries in the result that the rate of smoking and of lung cancer among women is fewer compared to the International rate. It also resembles most of the European countries in the result that squamous cell carcinoma is the most common pathological pattern, and the size of pulmonary resection is bigger than that in the developed countries where they have earlier diagnosis. Moreover, the rate of the sleeve resection surgery along with the rate of mortality resemble that of the International centers.
Lung cancer is the major cause of cancer death. S100A7
overexpression has been associated with early stages of
carcinomas . This study aimed to evaluate the levels of serum
S100A7 in lung cancer. Our study contains 63 patients of lung
cancer (46
newly diagnosis patients, 11 treated patients, 6
recurrence patients) and 15 healthy volunteers
Treatment plans were studied for patients with lung and esophageal tumors, patients were imaged using CT-Scan (PHILIP TYPE) and the images were sent to the Treatment Planning System-TPS (ECLIPS type), the system in which the doctor identified the tum
or and at-risk organs. Conventional 3D-Conformal Radiotherapy (3DCRT) and Intensity-Modulated Radiotherapy (IMRT) plans were created for the same patients. Treatment plans were compared according to the Dose Volume Histogram (DVH).It was observed that the radiation dose distribution of radiotherapy plans using IMRT technique better suited to tumor size (CTV) and protecting more organs surrounding the tumor, but it takes longer than 3DCRT technology. Therefore it is necessary to determine which patients should be treated with one technique (3DCRT or IMRT) or another technique depending on the full dose given to CTV and the time it generally takes.
