Do you want to publish a course? Click here

The Diagnostic Value of MRI Brain Epilepsy Protocol in Evaluation of Adults with Seizures

القيمة التشخيصية لبروتوكول الصرع في الرنين المغناطيسي للدماغ في تقييم النوبة الاختلاجية عند البالغين

1147   0   0   0.0 ( 0 )
 Publication date 2021
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




Ask ChatGPT about the research

Background and objectives: The advent of high-resolution MRI with a dedicated epilepsy protocol improves the ability to identify possible structural abnormalities that underlie seizure disorders. The aims of this study were to evaluate the diagnostic efficacy of standard MRI, identify whether there is an increase in the diagnostic yield with the addition of dedicated seizure protocol, and compare the diagnostic yields of MRI and electroencephalogram (EEG) individually and in combination. Subjects and Methods: This was a cross-sectional analytic study, included 100 cases who presented with seizure over 18 months. Patients underwent complete neurological examination, EEG, and MRI with a standard and dedicated epilepsy protocol. Results: We found epileptogenic lesions in MRI in 55.5. Mesial temporal lobe sclerosis was the most common epileptogenic lesion (45.5%). The diagnostic efficacy of MRI had increased with dedicated epilepsy protocol compared to standard protocol. Abnormal MRI and EEG were compatible in 21%. Conclusion and implications: Dedicated epilepsy protocol increased the diagnostic efficacy of brain MRI in detecting a structural epileptogenic lesion, with 100% of mesial temporal sclerosis, the most common lesion in our study, was detected only in dedicated epilepsy protocol and missed in standard protocol.

References used
Annegers JF, Hauser WA, Lee JR, Rocca WA. Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935 - 1984. Epilepsia 1995; 36:327

Artificial intelligence review:
Research summary
تتناول هذه الدراسة القيمة التشخيصية لبروتوكول الصرع في التصوير بالرنين المغناطيسي للدماغ في تقييم النوبات الاختلاجية عند البالغين. تهدف الدراسة إلى تقييم كفاءة الرنين المغناطيسي القياسي، وتحديد ما إذا كان هناك زيادة في القيمة التشخيصية باستخدام البروتوكول الخاص بالصرع، ومقارنة القيمة التشخيصية لكل من الرنين المغناطيسي وتخطيط الدماغ الكهربي (EEG) لدى البالغين الذين يعانون من نوبات اختلاجية. شملت الدراسة 100 حالة ممن راجعوا العيادة العصبية في مشفى تشرين الجامعي في اللاذقية وعانوا من نوبات اختلاجية خلال الأشهر الـ 18 السابقة. أظهرت النتائج وجود آفات صرعية في الرنين المغناطيسي بنسبة 55.5%، وكانت تصلب الفص الصدغي الأنسي الآفة الأكثر تواتراً بنسبة 45.5%. ازدادت القيمة التشخيصية للرنين المغناطيسي باستخدام البروتوكول الخاص بالصرع مقارنة مع البروتوكول القياسي، حيث توافق الرنين المغناطيسي مع تخطيط الدماغ الكهربي في 21% من الحالات. خلصت الدراسة إلى أن البروتوكول الخاص بالصرع يزيد من القيمة التشخيصية للرنين المغناطيسي في الكشف عن الآفات الصرعية البنيوية، مما يساهم في تحسين التشخيص والتدبير المبكر للمرضى.
Critical review
دراسة نقدية: تعد الدراسة ذات أهمية كبيرة في مجال تشخيص النوبات الاختلاجية، حيث تقدم دليلاً قوياً على فعالية البروتوكول الخاص بالصرع في تحسين القيمة التشخيصية للرنين المغناطيسي. ومع ذلك، يمكن توجيه بعض النقد البناء للدراسة. أولاً، حجم العينة قد يكون غير كافٍ لتعميم النتائج على جميع المرضى، لذا يفضل إجراء دراسات مستقبلية تشمل عينات أكبر. ثانياً، لم تتناول الدراسة بشكل كافٍ العوامل البيئية والجغرافية التي قد تؤثر على نتائج التشخيص، مما قد يحد من تطبيق النتائج في سياقات مختلفة. أخيراً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تضمنت مقارنة بين تقنيات تصوير أخرى مثل التصوير المقطعي المحوسب (CT) لتقديم صورة أكثر تكاملاً عن فعالية البروتوكولات المختلفة.
Questions related to the research
  1. ما هي الأهداف الرئيسية للدراسة؟

    الأهداف الرئيسية للدراسة هي تقييم الكفاءة التشخيصية للرنين المغناطيسي القياسي لدى مرضى النوبات الاختلاجية، وتحديد ما إذا كان هناك زيادة في القيمة التشخيصية باستخدام البروتوكول الخاص بالصرع، ومقارنة القيمة التشخيصية لكل من الرنين المغناطيسي وتخطيط الدماغ الكهربي لدى البالغين الذين يعانون من نوبات اختلاجية.

  2. ما هي النتيجة الرئيسية التي توصلت إليها الدراسة؟

    النتيجة الرئيسية التي توصلت إليها الدراسة هي أن البروتوكول الخاص بالصرع يزيد من القيمة التشخيصية للرنين المغناطيسي في الكشف عن الآفات الصرعية البنيوية، حيث أظهر البروتوكول الخاص بالصرع توافقاً أكبر مع تخطيط الدماغ الكهربي مقارنة بالبروتوكول القياسي.

  3. ما هي الآفة الصرعية الأكثر شيوعاً التي تم اكتشافها في الدراسة؟

    الآفة الصرعية الأكثر شيوعاً التي تم اكتشافها في الدراسة هي تصلب الفص الصدغي الأنسي، والتي شكلت 45.5% من الحالات التي أظهرت آفات صرعية في الرنين المغناطيسي.

  4. ما هي التوصيات التي خلصت إليها الدراسة؟

    خلصت الدراسة إلى توصية بإجراء المزيد من الدراسات الموسعة التي تشمل عدداً أكبر من المرضى وتبحث في كل آفة من الآفات الصرعية على حدة، نظراً للأهمية الواضحة للرنين المغناطيسي في تقييم مرضى النوبات الاختلاجية. كما أوصت بربط نتائج التصوير الطبي مع نتائج تخطيط الدماغ الكهربي والفحص العصبي الكامل للوصول إلى التقييم الأمثل والتدبير الأفضل.

rate research

Read More

This research is designed to study the diagnostic yield of brush cytology for biliary strictures. Brush cytology technique is of a great value to provide cytological samples during ERCP for patients with biliary strictures . The study included 34 patients with biliary stricture, ERCP was performed to all patients and cellular samples were taken using a brush for cytology . During the study period (one year) , the final diagnosis was made using a systematic approach based on clinical, radiological, laboratory or histopathological diagnosis . Sensitivity and specificity of brush cytology were studied . The sensitivity of biliary brushing was 57.1% , specificity was 100%, positive predictive value was 100% , negative predictive value was 76.9% and accuracy was 82% . Conclusions: Brush cytology has a very high specificity but an intermediate sensitivity for the diagnosis of malignant biliary strictures . Despite that , brush cytology is of a high diagnostic utility to distinguish between malignant and benign causes of biliary strictures .
Introduction : The main role of fine needle aspiration cytology (FNAC) lies in the differentiating between a malignant and benign thyroid nodule. It greatly influences the treatment decision. Aim : This study aimed to evaluate the accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of thyroid nodules by evaluating the cytology–histopathology correlation . Materials and Methods : This is a prospective study of 49 diagnosed cases of thyroid nodules who underwent FNAC and histological study of surgical biopsies for diagnosis at Tishreen University Hospital , during the period between march 2017 – march 2018 .The results were categorized according to Betheseda classification into: insufficient for diagnosis, benign, follicular lesion of undetermined significance, follicular neoplasm, suspicious for malignancy, and malignant sampling. The final histologic diagnosis was considered the gold standard. Results : The study included 49 cases presented with thyroid nodules who underwent diagnostic thyroid FNAC. Female to male ratio was 7.2:1, and the mean age was 43.6 years. Thirty –nine cases (79.6%) were diagnosed as benign, 3 cases (6.1%) as unsatisfactory , 2 cases (4.1%) as follicular neoplasm, 2 cases (4.1%) as suspicious for malignancy, 2 cases (4.1%) as malignant, and 1 case (2%) as follicular lesion of undetermined significance. Nodular goitre represented the majority of benign cases (62.8%), while papillary carcinoma was the most frequent malignant lesion (83.3%). Cytologic diagnoses were compared with their corresponding final histologic ones. FNAC achieved a sensitivity of 83.3%, a specificity of 97.4%, a positive predictive value of 83.3%, a negative predictive value of 97.4%, a false positive rate of 2.5% , a false negative rate of 16.6% , and a total accuracy of 95.5%. Conclusion : FNA cytology is a sensitive, specific, and accurate initial diagnostic test for the evaluation of patients with thyroid nodules.
Introduction: Urinary tract infections are very common in childhood (especially under the age of 5 years) and because of the large number of complications resulting from it (renal failure – hypertension- kidney scarring) had to be diagnosed and early treatment, although that urine culture is the standard Golden diagnosis, but its results are late to appear, Many studies have indicated an accompanying increase in platelet counts in urinary tract infections, so that platelet counts may be a vital indicator directed to it without asylum to the costly analyzes in its diagnosis. Objective: the objective of the following study is to assess the sensitivity and specificity of the plate count (PLT) in UTI. Methods: The study included 65 Patients (14 males, 51females) They were between (3-6) year with upper urine tract infections were diagnosed through symptoms, urological test, Serum tests, and radiology, who were admitted to the pediatric department at Tishreen University Hospital in Lattakia City. PLT was obtained through a complete CBC blood count (sensitivity and sensitization), and comparison of the ratio Percentage of Thrombocytosis between urine culture with Gram-positive germs and Gram-negative germs. Results: The study showed a good sensitivity=80.39% [75–84] to platelet counts compared to urine culture. it also showed statistically significant paper p-value=0.003 between platelet count and type of pathogen (positive or negative Gram) and the increase was more favorable to positive urine culture. Also showed that the average value of platelets is higher in culture a positive gram 521.9±90.9 x103 platelet/mcl than in gram negative 432.3±73.5 x103 platelet/mcl. Conclusion: higher Platelet numbers are a good analysis or sensitivity for the diagnosis of upper urinary tract infection in children with reliable urinary symptoms to start treatment. So that we get the results of culture urine .and the higher platelet count must be taken gram positive bacteria into account.
Flow cytometry became unavoidable step in the diagnosis of Acute Leukemia . However, accurate diagnosis is conditioned by using proper markers. Objective: to evaluate the quality of performance of four colors protocol, we used for immunophenotyping of acute leukemia in children.
The objective of this research is to insist on the most important symptoms and signs of appendicitis and diagnosis in a timely manner to avoid complications and deaths. The aim of the study was to establish diagnostic criteria for acute appendiciti s in children in the light of the data obtained from the study of a large number of patients with appendicitis and to determine the surgical indication to reduce complications and negative abdominal opening and to include the studied criteria in a spec ial scale in our patients to evaluate children with acute appendicitis depending On this scale. The study included 104 children who visited the Pediatric emergency department at Al-Assad University and University Hospital and Tishreen university Hospital with a complaint of abdominal pain between 2014 and 2016. The number of male patients was 76 patients and 28 females, abdominal pain was present in all patients, The following criteria were studied (abdominal pain, abdominal tenderness, rebound tenderness, ultra sound, leukocytosis, shift to left, fever,crp). These criteria were studied to diagnose acute appendicitis and to put them in a special scale for use in diagnosis or denial acute appendicitis. In comparison with international standards, we observed that the scale studied in our study is more objective and eliminates the subjective factor in the diagnosis of appendicitis.

suggested questions

comments
Fetching comments Fetching comments
Sign in to be able to follow your search criteria
mircosoft-partner

هل ترغب بارسال اشعارات عن اخر التحديثات في شمرا-اكاديميا