This research is designed to study the diagnostic yield of brush cytology for biliary
strictures. Brush cytology technique is of a great value to provide cytological samples
during ERCP for patients with biliary strictures .
The study included 34
patients with biliary stricture, ERCP was performed to all
patients and cellular samples were taken using a brush for cytology . During the study
period (one year) , the final diagnosis was made using a systematic approach based on
clinical, radiological, laboratory or histopathological diagnosis . Sensitivity and specificity
of brush cytology were studied .
The sensitivity of biliary brushing was 57.1% , specificity was 100%, positive
predictive value was 100% , negative predictive value was 76.9% and accuracy was 82% .
Conclusions: Brush cytology has a very high specificity but an intermediate
sensitivity for the diagnosis of malignant biliary strictures . Despite that , brush cytology
is of a high diagnostic utility to distinguish between malignant and benign causes of biliary
strictures .
ERCP is an im portant means of diagnosis and management of diseases of the biliary
and pancreatic ducts, and this procedure can be associated with certain complications
.This study was conducted to assess the frequency of complications following ER
CP, the
sample of the study consisted of 292 patients have adequate indication for ERCP. As
expected, Post ERCP pancreatitis scooped the highest percentage of complications, with
3.4% (by 38.4% of all complications), While post ERCP bleeding occurred in 4 patients
(1.4%). Post ERCP perforation occured in 3 patients (1.03%), Either post ERCP
cholangitis had occurred in 4 patients (1.4%). Cardiac and pulmonary complications were
rare (0.68 percent, 0.34%), respectively. Our study has recorded rare complication was an
impaction of basket within Vatter's ampulla, that occurred in 1 patient(0.34%).