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فعالية الكريم الموضعي المستخلص من كاسيا أمارا بتركيز 4% في علاج الوردية الحطاطية البثرية

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 Publication date 2018
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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Research summary
تتناول هذه الدراسة فعالية كريم موضعي يحتوي على 4% من مستخلص كاسيا أمارا في علاج الوردية الحطاطية البثرية، مقارنة بجل المترونيدازول 0.75%. شملت الدراسة 40 مريضاً تم تقسيمهم إلى مجموعتين عشوائياً، حيث استخدمت المجموعة الأولى كريم كاسيا أمارا والمجموعة الثانية جل المترونيدازول. تم تقييم الفعالية العلاجية من خلال مشعرات عدد الحطاطات والبثرات وشدة الحمامى وتوسع الشعريات. أظهرت النتائج أن كريم كاسيا أمارا كان فعالاً وآمناً ومكافئاً لجل المترونيدازول في علاج الوردية الحطاطية البثرية، مع تفوق طفيف للكاسيا أمارا في تقليل عدد الحطاطات والبثرات. لم يكن هناك فرق إحصائي هام بين المجموعتين من حيث التأثيرات الجانبية، التي كانت خفيفة وعابرة. توصي الدراسة بإجراء دراسات مستقبلية على مجموعات أكبر ومع أنواع أخرى من الوردية لتأكيد النتائج وتعزيزها.
Critical review
تعتبر هذه الدراسة خطوة هامة في تقييم فعالية مستخلص كاسيا أمارا في علاج الوردية الحطاطية البثرية، إلا أن هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة كان صغيراً نسبياً مما قد يؤثر على تعميم النتائج. ثانياً، لم يتم دراسة تأثير العلاج على المدى الطويل، حيث أن فترة المتابعة كانت قصيرة نسبياً. ثالثاً، لم يتم تقييم تأثير العلاج على نوعية حياة المرضى بشكل شامل. وأخيراً، كان من الممكن تضمين مجموعة أكبر من المرضى بمختلف درجات الوردية لتقديم صورة أكثر شمولية عن فعالية العلاج.
Questions related to the research
  1. ما هو الهدف الرئيسي من هذه الدراسة؟

    الهدف الرئيسي من الدراسة هو تقييم فعالية وأمان الكريم الموضعي المستخلص من كاسيا أمارا بتركيز 4% في علاج الوردية الحطاطية البثرية الخفيفة إلى المتوسطة الشدة، ومقارنته بجل المترونيدازول 0.75%.

  2. ما هي النتائج الرئيسية التي توصلت إليها الدراسة؟

    أظهرت الدراسة أن كريم كاسيا أمارا كان فعالاً وآمناً في علاج الوردية الحطاطية البثرية، وكان مكافئاً لجل المترونيدازول 0.75%، مع تفوق طفيف للكاسيا أمارا في تقليل عدد الحطاطات والبثرات.

  3. ما هي التوصيات التي قدمتها الدراسة؟

    توصي الدراسة بإجراء دراسات على مجموعات أكبر لتعزيز النتائج، ودراسة فعالية كريم كاسيا أمارا في أنواع أخرى من الوردية والأمراض المتعلقة بها، ومقارنته بالعلاجات الموضعية الأخرى، ودراسة فعاليته في الحالات الشديدة من الوردية.

  4. ما هي التأثيرات الجانبية التي تم ملاحظتها خلال الدراسة؟

    كانت التأثيرات الجانبية خفيفة وعابرة، وشملت جفاف الجلد، الحكة، حس الحرق والوخز، والتوسف، دون وجود فوارق هامة إحصائياً بين المجموعتين من حيث تواتر حدوث هذه التأثيرات.


References used
Baldwin HE.Psychosocial implications of rosacea .Dermatologist 2012
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