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Register a new userفعالية الكريم الموضعي المستخلص من كاسيا أمارا بتركيز 4% في علاج الوردية الحطاطية البثرية
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Added by
Damascus University رسالة ماجستير
Publication date
2018
fields
Medicine
and research's language is
العربية
Created by
Shamra Editor
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تطلق تسمية العد الوردي بشكل مكافئ للوردية ومن الأفضل تجنب هذه التسمية كي لا يحدث التباس مع العد الشائع الذي هو مرض يصيب الوحده الشعرية الزهمية
No English abstract
Artificial intelligence review:
Research summary
تتناول هذه الدراسة فعالية كريم موضعي يحتوي على 4% من مستخلص كاسيا أمارا في علاج الوردية الحطاطية البثرية، مقارنة بجل المترونيدازول 0.75%. شملت الدراسة 40 مريضاً تم تقسيمهم إلى مجموعتين عشوائياً، حيث استخدمت المجموعة الأولى كريم كاسيا أمارا والمجموعة الثانية جل المترونيدازول. تم تقييم الفعالية العلاجية من خلال مشعرات عدد الحطاطات والبثرات وشدة الحمامى وتوسع الشعريات. أظهرت النتائج أن كريم كاسيا أمارا كان فعالاً وآمناً ومكافئاً لجل المترونيدازول في علاج الوردية الحطاطية البثرية، مع تفوق طفيف للكاسيا أمارا في تقليل عدد الحطاطات والبثرات. لم يكن هناك فرق إحصائي هام بين المجموعتين من حيث التأثيرات الجانبية، التي كانت خفيفة وعابرة. توصي الدراسة بإجراء دراسات مستقبلية على مجموعات أكبر ومع أنواع أخرى من الوردية لتأكيد النتائج وتعزيزها.
Critical review
تعتبر هذه الدراسة خطوة هامة في تقييم فعالية مستخلص كاسيا أمارا في علاج الوردية الحطاطية البثرية، إلا أن هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة كان صغيراً نسبياً مما قد يؤثر على تعميم النتائج. ثانياً، لم يتم دراسة تأثير العلاج على المدى الطويل، حيث أن فترة المتابعة كانت قصيرة نسبياً. ثالثاً، لم يتم تقييم تأثير العلاج على نوعية حياة المرضى بشكل شامل. وأخيراً، كان من الممكن تضمين مجموعة أكبر من المرضى بمختلف درجات الوردية لتقديم صورة أكثر شمولية عن فعالية العلاج.
Questions related to the research
-
ما هو الهدف الرئيسي من هذه الدراسة؟
الهدف الرئيسي من الدراسة هو تقييم فعالية وأمان الكريم الموضعي المستخلص من كاسيا أمارا بتركيز 4% في علاج الوردية الحطاطية البثرية الخفيفة إلى المتوسطة الشدة، ومقارنته بجل المترونيدازول 0.75%.
-
ما هي النتائج الرئيسية التي توصلت إليها الدراسة؟
أظهرت الدراسة أن كريم كاسيا أمارا كان فعالاً وآمناً في علاج الوردية الحطاطية البثرية، وكان مكافئاً لجل المترونيدازول 0.75%، مع تفوق طفيف للكاسيا أمارا في تقليل عدد الحطاطات والبثرات.
-
ما هي التوصيات التي قدمتها الدراسة؟
توصي الدراسة بإجراء دراسات على مجموعات أكبر لتعزيز النتائج، ودراسة فعالية كريم كاسيا أمارا في أنواع أخرى من الوردية والأمراض المتعلقة بها، ومقارنته بالعلاجات الموضعية الأخرى، ودراسة فعاليته في الحالات الشديدة من الوردية.
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ما هي التأثيرات الجانبية التي تم ملاحظتها خلال الدراسة؟
كانت التأثيرات الجانبية خفيفة وعابرة، وشملت جفاف الجلد، الحكة، حس الحرق والوخز، والتوسف، دون وجود فوارق هامة إحصائياً بين المجموعتين من حيث تواتر حدوث هذه التأثيرات.
References used
Baldwin HE.Psychosocial implications of rosacea .Dermatologist 2012
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Objective: Keloid pose aesthetic and functional problems, in addition to being associated with disturbing clinical symptoms such as itching and pain, and current methods of treatment are limited in effectiveness. Clinical studies indicate that botuli
num toxin (BTA) may prevent the formation of keloid and treat it, so the aim of this research was to compare the effectiveness of topical injection of botulinum toxin versus topical steroid injection in the treatment of keloid. Methods: The research sample included 23 patients from the dermatology clinic at Tishreen University Hospital in Lattakia between 2019 and 2020, with keloids. The number of keloids registered with the studied sample was 30 distributed to two groups: Group A receiving IL steroid repeated every 4 weeks for six sessions, Group B IL BTA 5 IU /cm3 repeated every 8 weeks for three sessions. Objective parameters (hardness, elevation, pigmentation and vasscularity), subjective complaints (itching, pain, and tenderness), patient satisfaction, and side effects were evaluated. Results: There was a 58.4% decrease in the Vancouver scale for group A, and 65.8% for group B, without a statistical difference between the two groups (P <0.05). A noticeable decrease in tenderness 85.9% in treatment group A and 82.7% in treatment group B. A significant decrease in elevation in A 79.4% while B had a slight decrease of 27%. For vascularity we observed a slight decrease in treatment group A of 17.7% without statistical significance, whereas in treatment group B there was a decrease of 58%. The itching improvement in treatment group B was shown to be greater with statistically significant differences (P<0.05). Skin atrophy and telangiectasia were evident in 11 patients of group A. Conclusions: This study showed the efficacy and safety of topical toxin injection in treating keloid by improving objective and subjective criteria when compared to topical injection of corticosteroids. With fewer side effects reported for botulinum toxin.
Due to it`s several properties of Trypsin as an active enzyme in treating wounds, the
aim of this study was to evaluate the efficacy of this material with traditional treatments in
treating dry socket.
Methods:132 patients (20-65 years old) partic
ipated in this study.
The patient were distributed randomly into two groups.
The first group (group 1) was treated with Trypsin whereas the other (group 2) was
treated with traditional technique .
Patients were monitored, to asses healing process, after 24 hours, 48 hourse, and after
1 week.
Results: 43,9% of group 1 and 10,6% of group 2 had no pain P<0,05,wereas 81,8%
of group 1 and 43,9% of group 2 didn`t present dry socket P<0,05. Concerning infection ,7
cases of group 1 and 11 cases of group 2 had infection of soft tissue P<0,05.
Conclusions :Pain, dry socket, and soft tissue infection was less in casese treated
with Trypsin comparing with cases treated with traditional technique.
The primary goal of any surgery for cholesteatoma is complete
eradication of this lesion aiming to reach a dry ear and to prevent the
complications and recurrence. The second goal is to preserve hearing or to
improve it. This study aims to discuss
cases of Cholesteatoma treated by
canal wall-up mastoidectomy (Closed technique) and to determine the
efficacy of this technique by studying the recurrence rates and hearing
results.
the sample consisted of 36 patients who were admitted in alassad and tishreen
hospital between 2013-2016 with bacterial arthritis proved by clinical,radiological and
laboratory methods. They went uder surgical intervention ,during it,a continuous i
rrigation
system was accomplished according to designed plan. The irrigation period was 12 days
(mean) with mean hospitalization period 12 days. Irrigation fluid was considered regarding
to culture and susceptibility results in addition to antibiotic qualities .Results were
collected depending on joint functional activitiy return regarding to capacity,bearing and
stability(after a month-3 months- year),as well as natural laboratory and vlinical features
return .we used the criteria healing (irrigation handout). The joint functional activity
returned after a month in (70% mean) ,after 3 months in (77% mean), after a year in (89%
mean).while the clinical infection signs fell back after a week in (85% mean) ,after a
month in (92% mean), after 3 months in ( 97%). The laboratory signs fell back after a
month in (91% mean), after 3 months in (97% mean). A comparing was achieved between
these results and irrigation period ,hospitalization period by using CHI² test . The use of
continuous irrigation system in treatment of bacterial arthritis once it is diagnosed (in
regard to designed plan, irrigation fluid qualities and the host condition) improves the joint
functional activity and reduces hospitalization period so that ,it lessens economic load and
accelerates the return professional activity.
This study aims to show the effectiveness of hydroxyl urea in the treatment of
severe forms of sickle-cell anemia.
The study included 30 patients from patients with sickle cell anemia and who
reviewed the Blood clinics in AL- Assad University Hosp
ital .
We had studied patients treated with hydroxy urea for at least 6 months, where it was
compared to blood and clinical variables before and after hydroxy urea treatment.
The results showed an improvement in blood and clinical manifestations , and it was
noted a significant increase in the level of fetal hemoglobin, and a decrease in the level of
hemoglobin and sickle cell after hydroxy urea treatment.
hydroxy urea treatment also led to a clear increase in the level of total hemoglobin,
and a decrease in the value of total bilirubin.
Decrease in the number of the pain episodes that needed hospitalization, and the
number of times of blood transfusion after treatment, too.
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