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Register a new userThe prevalence of gastric intestinal metaplasia through upper gastrointestinal endoscopy and histological study, and association with Helicobacter pylori in the university hospitals of Tishreen university
انتشارُ الحَؤُولِ المِعَوِيِّ المَعِدِيِّ من خلالِ التنظيرِ الهضميِّ العُلويِّ و الدِّراسةِ النَّسيجيَّةِ و ترافُقِ المُلتويةِ البوَّابيَّةِ معهُ في المشافي الجامعيَّةِ بجامعةِ تِشرين
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
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يُعرَف الحَؤولَ المِعويَّ المعديَّ gastric intestinal metaplasia (GIM) كعاملِ خطورةٍ هامٍّ لسرطان المعدة الَّذي لا يزالُ رابعَ أكثرِ أنواعِ السَّرطاناتِ شُيوعاً و السَّببَ الرَّئيسيَّ الثَّانيَ للوفيَّاتِ السَّرطانيةِ في العالم بعد سرطانِ الرِّئة. ذكرت بعضُ الدِّراساتِ السَّريريةِ بأنَّ الحؤول المعوي يتحسَّنُ أو يهجع بعد علاجِ الإنتانِ بالملتوية البوَّابيَّة، و كنتيجةٍ لذلك فإنَّ استئصال الملتوية البوَّابيَّة هو واحدٌ من أكثرِ الأساليبِ الواعدة في منعِ حُدوثِ سرطانِ المعدة. الهدف من البحث استقصاءُ نِسبةِ انتشارِ الحَؤول المعويّ المعديّ و أنماطِه subtypes، و مُعدَّل ترافُقِ الإنتان بالمُلتويةِ البوَّابيَّة HP معه. حيث أُخِذت خزعات معدية من 200 مريضاً في مشافي جامعة تشرين بمحافظة اللاذقية في الفترة بين شهر كانون الثاني 2016 م و شهر نيسان 2017 م. تمَّ تلوينُ الخزعات بالهيماتوكسيلين إيوزين لتحديد نمط الحَؤُول المعوي, و تمَّ تحرِّي المُلتوية البوَّابيَّة بملوِّن غيمزا. بلغت نسبة انتشار الحؤول المعوي المعدي (16%). النمط التَّام كان أعلى انتشاراً من النمط غير التَّام. ترافقت الملتوية البوابية بنسبة (50%) مع الحؤول المعوي المعدي، دون وجود أهمية إحصائية ( P > 0.05). ترافق التهاب المعدة المزمن بنسبة (100%) مع الحؤول المعوي المعدي ( P Value = 0.02). الحؤول المعوي المعدي كان أعلى انتشاراً عند كبار السِّن. أظهرت دراستنا أنَّ الحؤول المعوي المعدي موجود بشكل ملحوظ في المرضى الخاضعين للتنظير الهضمي العلوي و الخزعات المعدية في منطقتنا. يُعتبر التهاب المعدة المزمن من أهم أسباب تطور الحؤول المعوي المعدي.
gastric intestinal metaplasia (GIM) is considered to be a precursor of gastric cancer which is still the fourth most common cancer and second leading cause of cancer related death worldwide after lung cancer. There is also a relationship between gastric intestinal metaplasia and H.pylory which is one of the most important factors predisposing it . As a result, H. pylori eradication is one of the most promising approaches in gastric cancer prevention. The aim of the study was investigated the prevalence of GIM and its subtypes, and the prevalence of H. pylori infection in GIM. the study was conducted on 200 patients who were undergoing esophagogastroduodenoscopy (EGD) with biopsy between January 2016 and April 2017, in the university hospitals of Tishreen university. Specimens were stained with hematoxylin and eosin to determine the pattern of intestinal metaplasia. And Helicobacter pylori was investigated by Giemsa staining. The prevalence of GIM was 16%. The prevalence of complete IM was higher than incomplete IM. The prevalence of H. pylori infection was 50% in GIM, without presence of statistical importance ) P > 0.05). The prevalence of chronic gastritis was 100% in GIM (P Value = 0.02). Gastric intestinal metaplasia was more prevalent in older patients. GIM is a common finding in patients undergoing EGD with biopsy in our region. Chronic gastritis is considered as the most important reason for the development of GIM.
References used
Antonioli DA. Gastric carcinoma and its precursors. In: Gastrointestinal Pathology, Goldman H, Appelman HD, Kaufman N (Eds), United States and Canadian Academy of Pathology Monograph in Pathology No. 31, Williams & Wilkins, Baltimore 1990. p.144
Correa P. The biological model of gastric carcinogenesis. IARC Sci Publ 2004; :301
Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996; 20:1161
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Introduction: Upper gastrointestinal system endoscopy is a safe and widely used procedure for diagnosis and treatment purposes. Endoscopic procedures can be painful and uncomfortable and patient cooperation is very important for a successful result.
Anxiety and stress are common problem in patients who have to undergo an invasive medical procedure. Anxiety before upper gastrointestinal endoscopy may have adverse consequences and can sometimes hamper successful completion of the procedure. In routine practice, verbal or written communication is used to inform the patient. Mostly this information is focused on the procedure itself and its complications. Aim: To investigate the effect of showing an informative video or providing verbal group education on anxiety and intra procedural co-operation among the patients undergoing upper gastrointestinal endoscopy. Material and methods: sixty gastrointestinal endoscopy patients were randomly assigned to video (20) or verbal information (20) groups or control (20) group. Patients in the video group watched a 7-minute-long video about the necessity of the endoscopic procedure, doctor and patient cooperation, and possible complications, emphasizing the possible feelings the patients might experience. The patients' situational anxiety was measured using the State-Trait Anxiety Inventory’s two scales (STAI-State and STAI-Trait). During the procedure we evaluate the patient's co-operation degree by using the Visual Analog Scale (VAS) with the doctors. Conclusions: It can be concluded that information by video helps reduce the anxiety of the patient, increases patient co-operation and the patient is much more readily convinced to undergo another procedure, in cases where a control is needed.
The aim of this study is to determine the incidence of helicobacter pylori
(HP) in patients with chronic gastroduodenitis and to compare the clinical
presentations between patients with positive HP chronic gastroduodenitis
and those with negative
HP. Also, To compare the endoscopic findings
between patients with HP positive gastroduodenitis and HP negative
children.
Gastroduodenoscopy was done for every child with abdominal pain
admitted at the children hospital-Damascus University between 2002-2003.
Mucosal biopsy was taken from every patient who had gastroduodenitis
diagnosed by gastroduodenoscopy.
The percentage of patients with gastroduodenitis having HP positive
erosions was 48.38 %.
Higher percentage of HP positive patient was more present in those with the
erosion and sub-atrophy forms.
Gastroesophageal reflux is one of the most common diseases in the world and his
most important symptoms is the heartburn. He requires surgical treatment in some
advanced cases.
The study was performed on 20 patients who underwent laparoscopic anti
-reflux
surgery in Al-Assad and tishreen university hospitals in Lattakia between 2011-2017 and
were followed for at least six months after surgery.
The analysis of the results showed a complete efficacy of this surgery in terms of
absence of clinical symptoms in patients and no need for medical treatment after surgery,
Absence of major complications and temporary swallowing only in 15% of cases.
Comparison with other studies has shown similar results in terms of effectiveness
and complications.
As a result of the study, we concluded that this surgery is low risk, highly effective,
and has few complications.
To study the prevalence of the diabetic hand in a group of type 2 diabetics,
comparing to age- sex matched non-diabetics control group, and to investigate clinical features among
diabetics with or without the diabetic hand.
20 Syrian adult patients from both sexes underwent study at Al-Mouassat
Hospital diagnosed with primary gastric E1 MALT lymphoma, Associated
with H.P. and treated only with H.P. eradication. This treatment led to H.P.
eradication in all patients (
100%), and complete regression of 85% of
Lymphoma.
Relapse did not appear during follow up period which exceeded 5 years in
all patients, 15% cured after chemotherapy without surgery nor
radiotherapy.
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