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Register a new userStudying the role of cervical injuries in the incidence of preterm rupture of membranes
دراسة دور أذيات عنق الرحم في حدوث انبثاق الأغشية الباكر
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Tishreen University ورقة بحثية
Publication date
2018
fields
Medicine
and research's language is
العربية
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مقدمة : يحدثُ انبثاق الأغشية الباكر بتمام الحمل في 10 % من الحمول تقريباً , في حين يختلط ما بين 3 – 5% من الحمول بحدوث انبثاق الأغشية الباكر قبل تمام الحمل . هدف البحث : دراسة دور أذيات عنق الرحم في حدوث انبثاق الأغشية الباكر(PROM) المواد و الطرق : إن هذه دراسة حالة – شاهد أجريت في قسم التوليد و أمراض النساء في مشفيي الأسد و تشرين الجامعي , اللاذقية , سوريا , في الفترة الممتدة ما بين كانون الثاني 2015 و حتى تموز 2017 . تكونت مجموعة الحالة من 90 مريضة انبثاق الأغشية الباكر مع قصة أو فحص سريري يقترح أذية رضية في عنق الرحم بعد استبعاد عوامل الخطورة التقليدية للانبثاق الباكر . تكونت مجموعة الشاهد من 50 سيدة حامل أكملت حملها بشكل طبيعي دون حدوث PROM
Introduction : Premature rupture of membranes (PROM) occurs in 10% of pregnancies , while 3-5% of pregnancies are complicated with Preterm rupture of membranes (PPROM) . Aim : To study the role of uterine cervix injuries in PROM . Materials and Methods :This is a case-control retrospective study conducted at Obstetrics and Gynecology Department at Al-Assad and Tishreen University Hospitals , Lattakia , Syria , during the period between January 2015 – July 2017 . The case group consisted of 90 PROM patients with a history or a physical examination suggesting a cervical traumatic injury after exclusion the traditional risk factors of premature rupture of membranes, The control group consisted of 50 healthy pregnant women who successfully completed the pregnancy without PROM.
References used
CASEY ML, MACDONALD PC. Interstitial collagen synthesis and processing in human amnion: a property of the mesenchymal cells. Biol Reprod 55: 1996; 1253
BRYANT-GREENWOOD GD. The extracellular matrix of the human fetal membranes: structure and function. Placenta 1998; 19:1
BENIRSCHKE, K, KAUFMANN, P. Pathology of the Human Placenta. Springer-Verlag, New York 1995. 268
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The study is carried on 65 pregnant patients attending the outpatient clinics and
inpatient department of Obstetrics and Gynecology of Al Assad University Hospital from
February- 2013 until February- 2014. They were divided to three groups. The fir
st is
preterm labor with intact membranes (25 patients). The second is PROM (20 patients). The
third one is control group (20 patients). All of them were submitted to ultrasonography to
find cervical changes (cervical canal length and diameter of internal os in order to predict
preterm delivery. Cervical canal length has a sensitivity of 91.43%, a specificity of 100%,
a positive predictive value of 100%, a negative predictive value of 76.92%, and a relative
risk (95% CI) of 4.33 (1.61-11.69) among patients with short cervical canal length and
those with normal cervix.
Diameter of internal os as a predictor of preterm delivery has a sensitivity of 60%, a
specificity of 60%, a positive predictive value of 84%, a negative predictive value of 30%,
and a relative risk (95% CI) of 1.2 (0.86–1.68).
Mankind is still suffering from many diseases , and with the
development of civilization there are many diseases that appear with
different clinical types , but tumors, especially malignant , are still very
important.
Cervical cancer is the secon
d common cancer in women , as it is the cause of
more than 200.000 deaths annually. Hence the importance of early detection
of cervical cancer and of decreasing mortality.
The research was conducted in the department of obstetrics and gynecology at Al-Assad university hospital in Lattakia in the period between (1/1/2014) – (30/6/2015). The study included (100) patient, who submitted to colposcopy and Papanicolaou smear
to detect the effect of early marriage (early onset of sexual activity) on colposcopic and cellular finding in cervix . The results in (early married women) group (50) patient were compared to control group from patients who (not early married women)group (50) patient. We found that there was important difference in the rate of abnormal colposcopic findings : This rate in early married women was (26%) and in the second was (12%). We also found that there was important difference in the rate of abnormal cellular findings: This rate in early married women was (18%) and in the second was (8%). This assure the effect of early onset of sexual activity (early marriage) on colposcopical and cellular finding in cervix with assuring on the importance of frequent colposcopy and Papanicolaou smear test.
Cervix cancer is one of the most important gynecological
cancers ,which is possible to be reduced by using early precancerous
detecting technics .
Objective : The aim of the study is to highlighten the colposcopy as a device
for early detection o
f precancerous lesions in the cervix , and compare the
results with histopathology .
This paper presents the application of electromagnetic wave
scattering in human cervical cells. Particularly, studying the effect
of morphological and physiological alterations on the properties of
light scattering. Tissue alterations are caused b
y multi-grade
dysplastic cervical cells and its internal structures.
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