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Register a new userنتائج العلاج الشعاعي لسرطان الحنجرة شائك الخلايا مرحلة أولى و ثانية دراسة إحصائية في الشعبة الأذنية بمستشفى البيروني الجامعي - جامعة دمشق
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Damascus University رسالة ماجستير
Publication date
2013
fields
Medicine
and research's language is
العربية
Created by
Shamra Editor
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الهدف من الدراسة: تقييم نتائج العلاج الشعاعي لسرطان الحنجرة شائك الخلايا في مراحله المبكرة T1N0M0,T2N0M0 في مركز العلاج الشعاعي بمستشفى البيروني الجامعي التصميم: دراسة إحصائية تراجعية . المكان : قسم أمراض الأذن و الأنف و الحنجرة و جراحة الرأس و العنق- وحدة الرأس و العنق - مشفى البيروني الجامعي-جامعة دمشق .
No English abstract
References used
1. Essential,K.J.Lee,MD,FACS. Otolaryngology-Head and Neck Surgery, 9th edition ,2010. Cancer of larynx ;27(596)
Cummings CW, Fredrickson JM, Harker LA,et,eds.Otolaryngology-Head and Neck Surgery, 5th edition . Vol 3 .St.Louis ; Mosby,2010
Scott-Brown's Otorhinolaryngology, Head and Neck Surgery 7th edition 2008
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Larynx cancer is the most common cancer of the head and neck with the exception of
the skin and it accounts for 2% of all cancer diagnoses, its genesis is directly associated
with alcohol drinking and smoking, squamous cell carcinoma (SCC) is the m
ost common
histological type (95%) of larynx cancer.
Aim: The purpose of this study was to evaluate 3D conformal radiotherapy of accelerated
system for early larynx cancer and to estimate acute and late toxicity which appear because
of irradiated normal tissues around the tumor (thyroid gland, spine cord, ….) and also to
evaluate the rate of recurrence and survival.
Materials and methods: The study was performed of 44 patients of scc larengeal cancer
stage T1/T2, that underwent RT (2015 – 2017), 84% with glottic cancer, the median age
was 63 years, all patients were treated 3D conformal RT, Total dose between (60-66) Gy,
2Gy/fraction (5 fractions in week).Our analysis was to evaluate the acute and late toxicity
dure and after radiotherapy, and also the rate of recurrence and survival.
Results: The most toxicity was dysphagia (42 PTs) 96%, radiodermitis (30 PTs) 70%, the
least toxicity was tooth damage. No evidence of late toxicity, the rate of recurrence (11
PTs) 25%, metastases occur in (1 PT). (6/ 41 PTs) 16.4% were dead.
Conclusion: Radiotherapy is the important role to control early larynx cancer, and 3DRadiotherapy
is giving a large dose to treat the tumor and save the normal tissues around
the tumor from effect of radiation, therefor absence the late toxicity.
This retrospective study is to correlate oral squamous cell carcinoma with age,
gender and location of lesion, and to investigate the correlation between the grade of the malignancy and
lymph nodes in patients of the faculty of dentistry, Damascus university.
Bladder cancer is the second most common urogenital tumor. The stage, grade,
number and diameter of urinary bladder cancer is an important factors in determining prognosis of the
disease. Early diagnosis and proper treatment are also critical to im
prove survival.
This retrospective study was performed to determine the clinico-pathological features of primary bladder
cancer at first presentation at Damascus University hospitals.
The research aims to make a statistical approach to the cases of esophageal atresia by
its types and incidence, and to study the surgical treatment outcome and choose the best
method of treatment and follow up.
The study included 27 newborn patien
ts admitted in the Neonatal Intensive Care Unit
at Al-Assad University Hospital and Tishreen University Hospital in Lattakia, due to
diagnosis of esophageal atresia or tracheoesophageal fistula, from the beginning of January
2010 until the end of 2015. 14 of patients were males and 13 were females. Gross
classification of esophageal atresia was used, type (C) was found in 21 cases, type (A) was
found in 4 cases, type (E) was found in 2 cases, while type (B) and (D) were not seen. We
studied The clinical symptoms in newborn patients with this malformation, radial and
laboratory findings and associated malformations. We used esophageal contrast study
insure the diagnosis when needed. With type (C), we did primary anastomosis in 20 cases
and cervical esophagostomy with gastrostomy in only 1 case. With type (A), we did
esophagostomy with gastrostomy in all cases. With type (E), we closed the fistula with
cervical approach in all cases. The survival rate was 70.4%. Spitz classification was used
for risk assessment. The incidence of complications included anastomotic leakage 30% and
anastomotic stricture 69.2%.
Late – Stage Laryngeal Carcinoma (T3-T4 ) Has A High Incidence Of Cervical
Metastasis . The Incidence Of Subclinical Metastasis Is Not Well Described In None Irradiation And
Irradiation Patients Initially Clinically T3,T4) With Negative Nodes Of Th
e Neck ,And The Treatment Of
These Patients Is Contraversal.
Identify The Incidence Of Subclinical Metastatic Disease In (T3,T4) ) With Negative Nodes Of The Neck
Undergoing Functional Neck Dissections With Laryngectomy. And Identify The Incidence Of Subclinical
Metastatic Disease In Those Patients Who Faild Radiotherapy. Are There Any Benefits Of Cts In Those
Patients? .And What Is The Most Aproprait Therapy?.
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