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Study of surgical treatment outcome for esophageal atresia

دراسة نتائج العلاج الجراحي لرتق المري

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 Publication date 2017
and research's language is العربية
 Created by Shamra Editor




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The research aims to make a statistical approach to the cases of esophageal atresia by its types and incidence, and to study the surgical treatment outcome and choose the best method of treatment and follow up. The study included 27 newborn patients admitted in the Neonatal Intensive Care Unit at Al-Assad University Hospital and Tishreen University Hospital in Lattakia, due to diagnosis of esophageal atresia or tracheoesophageal fistula, from the beginning of January 2010 until the end of 2015. 14 of patients were males and 13 were females. Gross classification of esophageal atresia was used, type (C) was found in 21 cases, type (A) was found in 4 cases, type (E) was found in 2 cases, while type (B) and (D) were not seen. We studied The clinical symptoms in newborn patients with this malformation, radial and laboratory findings and associated malformations. We used esophageal contrast study insure the diagnosis when needed. With type (C), we did primary anastomosis in 20 cases and cervical esophagostomy with gastrostomy in only 1 case. With type (A), we did esophagostomy with gastrostomy in all cases. With type (E), we closed the fistula with cervical approach in all cases. The survival rate was 70.4%. Spitz classification was used for risk assessment. The incidence of complications included anastomotic leakage 30% and anastomotic stricture 69.2%.


Artificial intelligence review:
Research summary
تهدف الدراسة إلى تقديم مقاربة إحصائية لحالات رتق المريء حسب نمطها وتواردها، ودراسة نتائج المعالجة الجراحية واختيار الطريقة الأمثل للعلاج ومتابعة المرضى. شملت الدراسة 27 وليداً تم قبولهم في شعبة الحواضن في مستشفيي الأسد وتشرين الجامعيين باللاذقية بين يناير 2010 وديسمبر 2015. تم استخدام تصنيف Gross لتحديد أنماط رتق المريء، حيث وُجد النمط (C) في 21 حالة، والنمط (A) في 4 حالات، والنمط (E) في حالتين. لم تُشاهد أي حالات من النمطين (B) و(D). تم إجراء مفاغرة بدئية في النمط (C) لدى 20 حالة، وتفميم مريء ومعدة لحالة واحدة فقط. في النمط (A) تم إجراء تفميم مريء ومعدة لدى جميع الحالات، وفي النمط (E) تم إغلاق الناسور بمدخل رقبي في جميع الحالات. بلغ معدل البقيا 70.4%، وتم استخدام تصنيف Spitz لتقدير درجة الخطورة. شملت المضاعفات تسريب المفاغرة بنسبة 30% وتضيق المريء بنسبة 69.2%.
Critical review
تعتبر هذه الدراسة خطوة مهمة في فهم ومعالجة رتق المريء والناسور الرغامي المريئي. ومع ذلك، هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة صغير نسبياً مما قد يؤثر على دقة النتائج. ثانياً، لم يتم تناول تأثير العوامل البيئية أو الوراثية بشكل كافٍ. ثالثاً، كان من الممكن تضمين مجموعة مقارنة من مستشفيات أخرى للحصول على نتائج أكثر شمولية. وأخيراً، يجب التركيز على تحسين تقنيات التشخيص المبكر لتقليل نسبة الوفيات والمضاعفات.
Questions related to the research
  1. ما هو الهدف الرئيسي من هذه الدراسة؟

    الهدف الرئيسي هو تقديم مقاربة إحصائية لحالات رتق المريء حسب نمطها وتواردها، ودراسة نتائج المعالجة الجراحية واختيار الطريقة الأمثل للعلاج ومتابعة المرضى.

  2. ما هي الأنماط الأكثر شيوعاً لرتق المريء وفقاً لتصنيف Gross في هذه الدراسة؟

    النمط (C) كان الأكثر شيوعاً حيث وُجد في 21 حالة، يليه النمط (A) في 4 حالات، والنمط (E) في حالتين.

  3. ما هو معدل البقيا الإجمالي للمرضى في هذه الدراسة؟

    معدل البقيا الإجمالي كان 70.4%.

  4. ما هي النسبة المئوية للمضاعفات المتعلقة بتسريب المفاغرة وتضيق المريء؟

    نسبة تسريب المفاغرة كانت 30%، ونسبة تضيق المريء كانت 69.2%.

Keywords

References used
CORAN, A. G.; KRUMMEL, T. M. Pediatric Surgery.7th.ed., Elsevier, Philadelphia, 2012, 1738
HAIGHT, C.; TOWSLEY, H. congenital atresia of the esophagus with tracheoesophageal fistula, Surg Gynecol Obstet, 1943, 76-672
GROSFELD, J. L.; ONEILL, J. A. Pediatric Surgery.6th.ed., Elsevier, New York, 2006, 2146
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