الهدف تحري تعبيرية البروتين كيناز المرتبط بالسيكلين CdK1, CdK2 في عينات من السرطان الفموي شائك الخلايا و في عينات من المخاطية الفموية الطبيعية سريريا و المقارنة بينهما.
Aim of study: study of the differences in the protein expression of
Cyclin-dependent Kinase CdK1, CdK2 in Oral Squamous Cell
Carcinoma (OSCC) and in clinically- normal oral mucosa.
References used
AhmedinJemal, Taylor Murray, Alicia Samuels,et al. Cancer Statistics, 2003. CA Cancer J Clin 2003; 53:5,.3322/canjclin.53.1.5
Alao John P, Simon C Gamble , Alexandra V Stavropoulou , et al. The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. Molecular Cancer 2006,5:7.1186/1476-4598-5-7
John P Alao The regulation of cyclin D1 degradation:roles in cancer development and the potential for therapeutic invention. Molecular Cancer 2007, 6:24.1186/1476-4598-6-24
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bones. Such defects are sometimes caused by resection of oral
squamous cell carcinoma (OSCC) yet the biologic effects of
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