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Histologic Analysis of Healing Process After Tooth Extraction With Ridge Preservation Using tricalcium phosphate

التحليل النسيجي لحديثة الشفاء التالي لقلع الأسنان و الحفاظ على السنخ باستخدام الفوسفات ثلاثية الكالسيوم

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 Publication date 2017
and research's language is العربية
 Created by Shamra Editor




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Background: socket preservation is a main therapeutic procedure to prevent severe marginal bone resorption after tooth extraction. The aim of this study is to investigate if there is any difference in the amount of new bone formation 4 months after extraction and ridge preservation compared to that after 6 months, Using tricalcium phosphate as a bone substitute. Methods: Minimally traumatic extraction with socket preservation using tricalcium phosphate was done at 30 single-rooted tooth sites in 28 patients. 15 sites healed for an average of 18 weeks (early healing group), and 17 sites were allowed to heal for an average of 27 weeks (delayed healing group) before collecting the bone samples . histological analysis was held to detect the percentage of new bone formation, residual substitute particles, and connective tissue/non-mineralized structures for each site. Results: All samples revealed a new bone formation, most of the residual substitute particles were surrounded by woven bone. No statistically significant differences in the amount of newly formed bone or residual substitute particles were found between the two groups. Overall, the early healing group demonstrated a mean of34.8% newbone, 20.5%residual substitute material, and 44.7% non-mineralized tissue. The delayed healing group showed mean values of 36%, 18.5%, and 45.5%, respectively. Conclusion: This study suppose that waiting for 6 months after tooth extraction and socket preservation using tricalcium phosphate does not provide a greater amount of new bone formation or less residual bone particles compared to that after 4 months.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة التحليل النسيجي لعملية الشفاء بعد قلع الأسنان والحفاظ على السنخ باستخدام الفوسفات ثلاثية الكالسيوم كبديل عظمي. هدفت الدراسة إلى مقارنة كمية العظم المتشكل حديثاً بعد 4 أشهر و6 أشهر من القلع. تم إجراء الدراسة على 30 موقعاً لأسنان وحيدة الجذر عند 28 مريضاً، حيث تم تقسيمهم إلى مجموعتين: مجموعة الشفاء المبكر (18 أسبوعاً) ومجموعة الشفاء المتأخر (27 أسبوعاً). أظهرت النتائج أن جميع العينات أظهرت تشكلاً عظمياً حديثاً، ولم يكن هناك فروق إحصائية دالة بين المجموعتين في كمية العظم المتشكل أو بقايا البديل العظمي. خلصت الدراسة إلى أن الانتظار لمدة 6 أشهر بعد القلع لا يوفر كمية أكبر من الأنسجة العظمية مقارنة بالانتظار لمدة 4 أشهر، مما يشير إلى إمكانية وضع الغرسات السنية بعد 4 أشهر من القلع.
Critical review
دراسة نقدية: على الرغم من أن الدراسة تقدم نتائج مهمة حول استخدام الفوسفات ثلاثية الكالسيوم كبديل عظمي، إلا أن هناك بعض النقاط التي يمكن تحسينها. أولاً، حجم العينة كان صغيراً نسبياً، مما قد يؤثر على قوة النتائج. ثانياً، لم يتم دراسة تأثير العوامل الأخرى مثل نوع الأسنان أو حالة المريض الصحية بشكل كافٍ. ثالثاً، كان من الممكن أن تكون الدراسة أكثر شمولية إذا تم مقارنة الفوسفات ثلاثية الكالسيوم ببدائل عظمية أخرى. أخيراً، لم يتم متابعة المرضى لفترة طويلة بعد وضع الغرسات، مما يجعل من الصعب تقييم النجاح الطويل الأمد للغرسات.
Questions related to the research
  1. ما هو الهدف الرئيسي من الدراسة؟

    الهدف الرئيسي هو مقارنة كمية العظم المتشكل حديثاً بعد 4 أشهر و6 أشهر من قلع الأسنان باستخدام الفوسفات ثلاثية الكالسيوم كبديل عظمي.

  2. ما هي الطريقة المستخدمة في الدراسة؟

    تم قلع الأسنان بحد أدنى من الرض وملء أجواف القلع ببديل عظمي من الفوسفات ثلاثية الكالسيوم، ثم تم تقسيم المرضى إلى مجموعتين: مجموعة الشفاء المبكر (18 أسبوعاً) ومجموعة الشفاء المتأخر (27 أسبوعاً).

  3. ما هي النتائج الرئيسية التي توصلت إليها الدراسة؟

    أظهرت النتائج أن جميع العينات أظهرت تشكلاً عظمياً حديثاً، ولم يكن هناك فروق إحصائية دالة بين المجموعتين في كمية العظم المتشكل أو بقايا البديل العظمي.

  4. ما هي التوصيات التي خلصت إليها الدراسة؟

    توصي الدراسة بوضع الغرسات السنية بعد 4 أشهر من القلع والتطعيم العظمي ببدائل مكونة من الفوسفات ثلاثية الكالسيوم، لأن نسبة نجاحها تماثل تلك التي بعد 6 أشهر.


References used
YAO, J., et al., What do patients expect from treatment with Dental Implants? Perceptions, expectations and misconceptions: a multicenter study. Clin Oral Implants Res, 2016
GUILLAUME, B., Dental implants: A review. Morphologie, 2016
SCHROPP, L ,.et al., Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Periodontics Restorative Dent, 23(4): 2003.p. 313-23
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