ضمت الدراسة 32 مريضاً يعانون من وحمة قربة النبيذ ، خضع كل منهم إلى 4 جلسات علاجية بفاصل 8 أسابيع بالليزر الصباغــي النابض 585 ن م مع جهاز تبريد هوائــي, بزمن نبضة 0.5 مل ثا، و قطر شعاع ليزري ثــابت 7 ملم مع مجــال تدفق طاقة ليزرية يتراوح بين 5- 6.5 جول / سم2 .
أظهرت النتائج تحسناً في لون الوحمات عند تكرار الجلسات العلاجية، و بعد الجلسة الرابعة كانت درجة التحسن جيدة أو ممتازة عند 69% من المرضى. لوحظ ظهور فرفرية عابرة مترافقة مع ألم محتمل بعد كل جلسة مباشرة عند 87.5% ، تقشر عند 25% ، نقص التصبغ عند 9% ، فرط التصبغ عند 6%. و كانت كلها خفيفة و لم يزداد حدوثها مع تكرار الجلسات العلاجية.
لقد بينت نتائج هذه الدراسة أن الليزر الصباغي النابض بطول موجة 585 ن م فعال في معالجة وحمات قربة النبيذ.
Thirty-two patients with port-wine stain were included in this study. The 585 nm
pulsed dye laser treatment with an air cooling device was repeated 4 times at 8 – week
intervals with a setting of 0.5 ms pulse duration and an average energy fluence 5 - 6.5 J/
cm2, using 7 mm spot size.
The results revealed improvement of port-wine stains after multiple treatments , and
69% of the patients achieved good or excellent clearance after the fourth treatment.
Transient purpura and tolerable pain were noted immediately after each treatment (87.5%),
crusting (25%), hypopigmentation (9%), hyperpigmentation (6%) were also mild and their
occurrence didn’t increase by repeating treatment.
The results of this study indicated that the 585 nm PDL is effective and well tolerated
in the treatment of port wine stain.
References used
CHAPAS AM, ECHHORST K, GERNEMUS R G. Efficacy of early treatment of facial port wine stains in newburns, arview of 49 cases. Laser Surg Med – 2007, 39 (7) : 563 – 8
ENJOLRAS O, RICHE MC , MERLAND J. Facial port wine stains and sturg weber syndrome. Pediatrics 1985,76(1) : 48 – 51
YANG MU , YAAROSLAVESKY AN, FARINELLI WA, FLOTTE TJ, RISDIAS F, TSAO SS. Long – pulsed NDyag laser treatment of port wine stains. J Am Acad Dermatol 2005, 52 (3pt1), 480 -90
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