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Register a new userIleal Pouch - Anal Anastomosis (IPAA) Study of 15 Cases
مفاغرة الجيب الدقاقي على الشرج: خبرة 15 حالة
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Damascus University ورقة بحثية
Publication date
2009
fields
Medicine
and research's language is
العربية
Authors
عبد الغني الشلبي( باحث )
Created by
Shamra Editor
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تقييم المعالجة الجذرية لآفات كولونية تترافق باحتمال خباثة مرتفع (داء البوليبات العائلي و التهاب الكولون القرحي) من خلال استئصال الكولون التام و تصنيع الجيب الدقاقي و مفاغرته على الشرج (IPAA) بحيث يتم المحافظة على السبيل الهضمي دون الضرورة لتحويل محتويات الأمعاء عبر جدار البطن.
Evaluation of radical surgical treatment of colonic lesions which have the potential for malignant transformation, namely familial adenomatous polyposis (FAP) and ulcerative colitis (UC), by performing total proctocolectomy with ileal pouch-anal anastomoses (IPAA). This technique helps preserving the continuity of the gastrointestinal tract without the need for external enteral diversion.
References used
Kelly KA. Anal sphincter-saving operations for chronic ulcerative colitis. Am J Surg. 1992; 163: 5-11
Setti-Carraro P, Ritchie JK, Wilkinson KH, et al. The first 10-years experience of restorative proctocolectomy for ulcerative colitis. Gut. 1994; 35: 1070-1075
Parc YR, Moslein G, Dozois RR, et al. Familial adenomatous polyposis: results after ileal pouch-anal anastomosis in teenagers. Dis Colon Rectum. 2000 Jul;43(7):893-8
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Background : Molluscum contagiosum is one of the commonest cutaneos viral infections in
children . Although there is no specific treatment for this infection many therapeutic modalities
have been used with different success rates , including curett
age, trichloroacetic acid , and
cryotherapy .
All treatment modalities are associated with substantial pain, tissue destruction, and
frequent recurrence.
There are other modalities that can be applied by parents and less side effects , such as using
tretinoin and KOH .
In our study , we compare between KOH which dissolves keratin and penetrate deeply the
skin , and tretinoin which damages the viral protein – lipid membrane
Objective : To compare the efficacy and side effects of KOH 15% solution with tretinoin
0.05% cream for treatment of molluscum contagiosum .
Material and methods : Total 52 patients with molluscum contagiosum were enrolled in this
study, from 2013 to 2014 , from Dermatology Department of Al Assad University outpatients,
Lattakia .We have designed a questionnaire include personal factors In addition to the tables to
compare all of KOH (15%) solution and teritnoian (0.05%) cream in terms of effectiveness in the
treatment and side effects.
Results : Mail : female ratio was (1.48 : 1) , age onset was higher at first decade (67.3%).
The most common involved site was the trunk ( 42.3 %) .
Both of the study treatment regimens have advantage over other treatment options as they
are locally applicable , less traumatic and painful .
Because of these characteristics , they can be easily applicable for the treatment of
Molluscum Contagiosum .
During the treatment period , using KOH (15%) showed cure rate ( 75%) after two weeks of
treatment , while using tretinoin (0.05%) showed cure rate (20.8%) after two weeks, and most of
the patients need four weeks and even more
Conclusion : The result of both KOH and tretinoin showed good response , well tolerated by
children but between the two , KOH showed fast recovery and most lesions were resolved before 4
week . The side effects could be minimized if applied as stated above . On the other hand , tretinoin
showed delayed response and even some of lesion extended beyond 4 week but the side effect were
less , and hence can be used in recurrent cases.
Background& Objective: The aim of this study was to know the Allele frequencies for the 15 STR loci in the sample in Aleppo in Syria.
Materials & Methods: Allele frequencies for the 15 STR loci included in the PowerPlex16 PCR Amplification Kit panel
from (Promega, Madison, USA) according to manufacturer’s instructions
(D3S1358, TH01, D21S11, D18S51, PentaE, D5S818, D13S317, D7S820, D16S539, CSF1PO, PenyaD, vWA, D8S1179, T, POX , FGA) and several statistical parameters were estimated from a sample of 127 unrelated individuals representing all ethnic groups in Aleppo in Syria . DNA was extracted from blood samples using QIAmp1 DNA Mini Kit (QIAGEN, Hagen, Germany) according to manufacturer’s instructions and the PCR products were typed using an ABI PRISM 310 Genetic Analyzer (Applied Biosystems, Foster City, CA, USA)). The results were analyzed using GeneMapper ID v3.0 software (Applied Biosystems). Several forensic and population parameters such as heterozygosity, polymorphic information content (PIC), power of discrimination (PD), power of exclusion (PE) and the paternity index (PI)) were calculated using Microsoft Excel-2007. A p-value of the 15 loci were estimated by using the statistical Microsoft Windows 2007 to verify whether the genotype distribution conformed to Hardy-
Weinberg equilibrium predictions.
Results : We compared our data with other data sets from published studies of individuals from Turkey, Morocco and Iraq, our data indicate that standardized multilocus STR panels may be a useful forensic tool which can be applied for identification purposes also in the Syria population.
Conclusion: Our Data may be a useful forensic tool which can be applied for identification purposes also in the Syria population.
As dental caries are among the most common chronic diseases, the study of their prevalence and severity in a specific population area can contribute to constructing necessary plans for treatment and prevention.
This study aimed to assess the rate
of prevalence and severity of dental caries in
13 -15 years – old children in Lattakia City and to study the effects of the different factors and their relation to the grade of the severity of the dental caries.
The study was conducted on 1680 children. The sample was divided into four main groups, depending on the grade of severity of the dental caries. The analysis of data showed that the prevalence of dental caries was 67.1±1.92% and the DMFT value was 2.35. The study also showed that mother feeding, the factor of dental care and socioeconomical factors are important in all groups
Background& Objective:Vascular rings are unusual rare congenital anomalies .Its incidence is less than 0.2%.Most of these defects are discovered early in infancy or childhood .They result in complete or partial encirclement of the trachea and/or esop
hagus .Some vascular rings are associated with other congenital heart defects, others may be isolated deficits. We present here eleven cases which we have encountered since the mid of 2009.These cases were managed surgically with good results .Through this study, we aim at demonstrating how to treat these cases surgically and to clarify the best approach for each case.
Materials & Methods: A retrospective study at Damascus University Cardiac Surgery Hospital in the period between 2009 to 2010 was conducted.11 patients with diagnosed vascular rings underwent surgical repair.
Results: Ages ranged between 1.5 months to 5 years with almost equal sex distribution. Most complaints were respiratory. Vascular rings include double aortic arche, aberrant left Subclavian artery and aberrant right Subclavian artery .Associated defects were in54% of cases. No complications were noticed postoperatively or in the follow up period which extended between 7 and10 months' .Remarkable relief and symptoms release were achieved postoperatively.
Conclusion: Surgery affords excellent long-term resolution of symptoms. Early diagnosis and surgery are imperative to reduce the long-termsequels.
Interpretability or explainability is an emerging research field in NLP. From a user-centric point of view, the goal is to build models that provide proper justification for their decisions, similar to those of humans, by requiring the models to sati
sfy additional constraints. To this end, we introduce a new application on legal text where, contrary to mainstream literature targeting word-level rationales, we conceive rationales as selected paragraphs in multi-paragraph structured court cases. We also release a new dataset comprising European Court of Human Rights cases, including annotations for paragraph-level rationales. We use this dataset to study the effect of already proposed rationale constraints, i.e., sparsity, continuity, and comprehensiveness, formulated as regularizers. Our findings indicate that some of these constraints are not beneficial in paragraph-level rationale extraction, while others need re-formulation to better handle the multi-label nature of the task we consider. We also introduce a new constraint, singularity, which further improves the quality of rationales, even compared with noisy rationale supervision. Experimental results indicate that the newly introduced task is very challenging and there is a large scope for further research.
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