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Register a new userEffect of an aqueous extract of oleander plant according to white created albino mouse which has got diabetes
تأثير المستخلص المائي لأوراق نبات الدفلة في الفئران البيضاء المستحدث فيها داء السكري
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تمّ إجراء البحث بهدف دراسة تأثير المستخلص المائي لأوراق نبات الدفلة في مستوى سكر الدم و الكوليسترول الكلي و الغليسيريدات الثلاثية للفئران المستحدث فيها داء السكري . و بينت النتائج مايلي: ارتفاع معنوي في تركيز كل من الغلوكوز و الكوليسترول و الغليسيريدات الثلاثية في مصل دم الفئران المستحدث فيها داء السكري ، و انخفاض الوزن بالمقارنة مع الشاهدة. أدى الحقن بالمستخلص المائي لأوراق نبات الدفلة بجرعة 200ملغ/كغ من وزن الفأر و لمدة عشرة أيام الى انخفاض معنوي بتركيز الغلوكوز و معدل الكوليسترول الكلي و الغليسيريدات الثلاثية ،كما عاد الوزن إلى ما كان عليه قبل الحقن.
This research has done in aiming for the effect of extract of Nerium oleander plant in the level of blood sugar and total glucose , triple alglesiredat and total cholesterol on created albino mouse which has got diabetes. The results showed the following: - A Significant increase in the concentration on bothglucose, triple alglesiredat and cholesterol through a serum in the blood of created albino mouse which has got diabetes, while the weight decreases comparing to the control. - The injection of Aqueous extract led oleander leaves plant with dose of 200 mg / kg of mouse weight for a period of ten days to a significant decrease of concentration on glucose ,the rate of total cholesterol and triple alglesiredat, in addition to, the weight has returned to what it was before the injection.
References used
ABDULKAREEM,K.F.; ULAIWI,H.KH;MOHAMMED,H.R;HARFSH.A.H The effect of experimentally indused hyperglycemia by alloxan on some hematological parameters in rabbits. Wasit Journal for Science & Medicine,2(2),2009, 186
Al-FARWACHI, M.I. In vitro and in vivo Immunomodulatory activities of Nerium oleander, aqueous leaf extract in Rabbits. J Anim Vet Adv, 6(9),2007,1047-1050
AL-HILFY,J. Effect of Green Tea Aqueous Extract on Body Weight, Glucose Level, and Kidney Functions in Diabetic Male Albino Rats.Journal of AL-Nahrain university science,vol.15(3),2012,161-166
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It was used in this study (15) of the female mice . They were divided into three
groups : control , and two experimental groups (five mice in each group) .The control
group was given distilled water, while the first experimental group was received
only
Paraben daily ( 250 mg / kg of body weight). As the second experimental group was
received daily together of Paraben and aqueous ginger extract ( 250 mg / kg of paraben and
250 mg / aqueous ginger extract ) for (18 ) day .
Many T2D use CAO as a laxative. We did not find sufficient research to explain CAO's potential effect on the levels of HbA1c in T2D patients. This study will study this effect. Rats (n=80) were divided into eight groups (n=10). Five groups (n=50) wer
e injected with streptozotocin intravenously to induce T2D. One group was given CAO with empagliflozin, and the second was assigned CAO only daily. The third was assigned CAO every two days, with empagliflozin, which was given daily. A fourth was assigned CAO alone daily. Also, the fifth was given empagliflozin alone. In the healthy groups, one group was given CAO, and the other was given empagliflozin. Also, the last healthy group was not assigned any drug. CAO's result on HbA1c in healthy rats was noted to decrease when delivered alone for eight weeks. HbA1c of the diabetic groups showed no significant difference (P-value<0.05) when comparing the rats given CAO with empagliflozin, and the rats were given CAO only. There was also no noticeable effect among the groups of rats given CAO daily and every two days. This study explains that CAO does not lead to a significant difference in HbA1c levels in diabetic rats, even it did for healthy rats, and if given alone, CAO could affect HbA1c levels if given over a long period. Also, CAO has a noticeable impact on experimental rats that co-administered Empagliflozin on HbA1c levels, and that Empagliflozin effect is not significantly affected if taken with CAO.
The present study aimed to investigate the effect of calyx aqueous extract of Hibiscus
sabdariffa on liver enzymes Alanine and Aspartate Transaminases (ALT and AST)level.
(12) Rabbits were used and divided into two groups : (6) the experimental gro
up and
(6) control group ,the control group became distilled water , while the experimental group
received aqueous extract, that was administrated orally in adose of150 mg / kg body
weight (b.w.) daily for28 days .Then blood was collected each 48 hours , the serum
samples were taken and prepared to the biochemical tests to determine Alanine and
Aspartate Transaminases (ALT and AST)level.
This study was conducted in the laboratories of the Faculty of Science In the spring
on 2013, after being subjected to gavage for 4 weeks through a standard diet supplemented
fat by 3% to two groups (6animales per group) the experimental group beca
me aqueous
extract 150 mg/kg Body weight for 4weeks while the control group became standard food
and tap water ad libitum.
The Blood samples were collected each week, and then the serum samples were
taken to the biochemical tests to determine total cholesterol, triglycerides and glucose
levels in biochemistry laboratory of the Institute of Intermediate medical in Tishreen
University.
The research was conducted to study the resistance of Nerium plant which are planting on
sides of roads and the cities portals. The research was performed by studying the leaves of
Nerium plant, through studying the length and weigh of the leaf, an
d its area and water
content. In addition to studying the wools and hiatus and chlorophyll concentration, and
compared the results between the polluted region which is the entry of Banias City, and the
control one which is the gardens of Tishreen University.
Results showed non significant reduction in length, weight and area of the leaf in the
polluted region compared with the control one. It attained (16.2 cm, 0.97 g and 26.3 cm2),
respectively in the polluted region. Where it was (17.8 cm, 1.25 g and 27.7 cm2), for
control region, respectively. Also, there was no significant differences in water content
between the two studied regions. It attained respectively (52.2 and 53.9 %).
Our results showed:
- That a number of hiatus decreased, whereas the wools increased in the polluted region
compared with control region insignificantly. The mean of a number of it was 12 in
polluted region, compared with 14 in the control region.
- A simple insignificant reduction in the concentration of chlorophyll A in polluted region
compared with the control, where it attained (0.93 and 0.98), respectively.
The Nerium oleander plant was resistance and tolerance to the air pollution.
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