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Study of Serum B-HCG Positivity Regression after Hydatidiform Mole in a Sample from the Department of Obstetrics & Gynecology at Damascus University Hospital

دراسة تراجع إيجابية قيم B – HCG المصلي عقب الرحى العدارية في عينة من مريضات مستشفى دار التوليد الجامعي بدمشق في المدة بين ( 2007-2009 )

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 Publication date 2011
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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Gestational trophoblastic disease is a group of disorders characterized by elevated HCG, a constellation of clinical symptoms, and may be classified into benign and malignant conditions . To evaluate spontaneous regression curves of B-HCG in patients with complete mole and partial mole.


Artificial intelligence review:
Research summary
تتناول هذه الدراسة تقييم منحنى التراجع لمستوى B-HCG في مريضات الرحى العدارية التامة والجزئية في مستشفى دار التوليد الجامعي بدمشق خلال الفترة من 2007 إلى 2009. أمراض الأرومة الغاذية الحملية هي مجموعة من الاضطرابات التي تتصف بارتفاع مستوى HCG في المصل وتتنوع بين أمراض سليمة وخبيثة. تم جمع عينات دموية من جميع المريضات المحولات إلى المستشفى لقياس مستويات B-HCG باستخدام تقنية ELFA. أظهرت النتائج أن 81.7% من الحالات شهدت تراجعًا عفويًا لمستوى B-HCG بعد التجريف، في حين تم تشخيص 18.3% من الحالات على أنها مرض الأرومة الغاذية المستمر بناءً على مستويات B-HCG المتسلسلة. خلصت الدراسة إلى أنه لا يوجد اختلاف في زمن المتابعة بين الرحى التامة والجزئية، وأن مستوى HCG غير القابل للكشف بعد التجريف يكفي لضمان التراجع في مريضات الرحى العدارية.
Critical review
دراسة نقدية: تعتبر هذه الدراسة مهمة لأنها تقدم بيانات محلية حول تراجع مستوى B-HCG في مريضات الرحى العدارية، مما يساهم في تحسين التشخيص والعلاج في المنطقة. ومع ذلك، يمكن توجيه بعض الانتقادات البناءة للدراسة. أولاً، حجم العينة قد يكون محدودًا نسبيًا، مما قد يؤثر على تعميم النتائج. ثانيًا، لم يتم التطرق بشكل كافٍ إلى العوامل المؤثرة الأخرى التي قد تؤثر على مستويات B-HCG مثل العوامل الوراثية أو البيئية. أخيرًا، كان من الممكن أن تكون الدراسة أكثر شمولاً إذا تضمنت متابعة طويلة الأمد للحالات لتقييم النتائج على المدى البعيد.
Questions related to the research
  1. ما هو الهدف الرئيسي من هذه الدراسة؟

    الهدف الرئيسي هو تقييم منحنى التراجع لمستوى B-HCG في مريضات الرحى العدارية التامة والجزئية في مستشفى دار التوليد الجامعي بدمشق.

  2. ما هي النسبة المئوية للحالات التي شهدت تراجعًا عفويًا لمستوى B-HCG بعد التجريف؟

    81.7% من الحالات شهدت تراجعًا عفويًا لمستوى B-HCG بعد التجريف.

  3. ما هي التقنية المستخدمة لقياس مستويات B-HCG في الدراسة؟

    تم استخدام تقنية Enzyme Linked Fluorescent Assay (ELFA) لقياس مستويات B-HCG.

  4. ما هو الاستنتاج الرئيسي للدراسة بشأن متابعة مستوى HCG بعد التجريف؟

    الاستنتاج الرئيسي هو أن مستوى HCG غير القابل للكشف بعد التجريف يكفي لضمان التراجع في مريضات الرحى العدارية.


References used
Szulman AE. Syndromes of Hydatidiform moles- partial vs. complete.J repord Med 1984; 29:788 – 91
Kajii T, Ohama K. Androgenetic origin of Hydatidiform mole. Nature 1977; 268: 633 – 4
Pattillo R A sasakis, katayama KP, Roesler M, Mattingly RF.Genesis of 46 XY Hydatidiform mole. Am J Obstet Gynecol 1981; 141: 104 -5
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