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Study of Serum B-HCG Positivity Regression after Hydatidiform Mole in a Sample from the Department of Obstetrics & Gynecology at Damascus University Hospital

دراسة تراجع إيجابية قيم B – HCG المصلي عقب الرحى العدارية في عينة من مريضات مستشفى دار التوليد الجامعي بدمشق في المدة بين ( 2007-2009 )

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 Publication date 2011
  fields Medicine
and research's language is العربية
 Created by Shamra Editor




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Gestational trophoblastic disease is a group of disorders characterized by elevated HCG, a constellation of clinical symptoms, and may be classified into benign and malignant conditions . To evaluate spontaneous regression curves of B-HCG in patients with complete mole and partial mole.

References used
Szulman AE. Syndromes of Hydatidiform moles- partial vs. complete.J repord Med 1984; 29:788 – 91
Kajii T, Ohama K. Androgenetic origin of Hydatidiform mole. Nature 1977; 268: 633 – 4
Pattillo R A sasakis, katayama KP, Roesler M, Mattingly RF.Genesis of 46 XY Hydatidiform mole. Am J Obstet Gynecol 1981; 141: 104 -5
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The study was carried out in Al-Assad University Hospital in Lattakia in surgery department for a period of two years (2014 – 2016). There were 52 patients with 104 undescended testises , their ages were between (6 months -5 years) .The objects of this study were as following: 1- study the result of treatment of B-HCG for bilateral cryptorchidism. 2- Study the optimal age for the application of hormonal treatment with B HCG . Ultrasound (US) was done to 39 patients (75%) to find the abnormalities of urinary tract, and the results were negative. The mean age was 2,5 . There were 29 patients (55.77 %) who were less than 2 years of age. Patients were followed for six months . There was success after six months of treatment 34,61 % of the total sample for bilateral cryptorchidism , 13,64 % of the total sample for one side . if treatment was early , the success rate would be better . the preferred age for treatment of B Hcg is less than 2 years of age .
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This study aims to treat all cases of choriocarcinoma using the national chemotherapy courses, and analyzing the results of treatment to assure that we are confirmed by the course (after proving its affectivity) and to avoid missed and unorganized treatments, which worsen the prognosis.
- Purpose: To study the reality of hydramnion in the Department. To use the Amnionic Fluid Index ( AFI ) sonarographycally for severity classification of hydramnion .To use Indomethacin for tretment and to study it`s effect on the fetal cardiac sy stem. - Methodology: Prospective study. - Setting: Department of Obstetrics and Gynecology, Damascus. - Subject: 132 women with hydramnios and 194 with uneventfull pregnancy. - Results: Prevalence rate is (0,85 %). The cause is known in (53,8%) of cases and the most common cause was a defect in the fetal nervous system. Most cases are classified by AFI as severe in (53,6%). All symptoms of hydramnios are decreased by using Indomethacin and the fetal cardiac system was not affected. - Conclusion: The medical tretment of hydramnios is effective and does n`t affect the fetal cardiac system . But, imperative research be continued.
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