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Effct of Soft Laser on the Oral Mucosa in Vivo (Syrian Hamstar)

أثر تطبيق الليزر الطري في الغشاء المخاطي الفموي الطبيعي عند الأحياء (الهامستر السوري)

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 Publication date 2011
  fields Dentistry
and research's language is العربية
 Created by Shamra Editor




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several articles on animal model and laboratory investigations Indicate that soft laser induce cellular and tissue motivation and heals wounds. Ami of the study: to investigate histological modification in oral squamous non-keratinized epithelium upon applying soft laser in several doses and studding the alteration in keratinization and the possibility to have neoplastic transformation.

References used
Cobb, C. M. , Lasers in periodontics: a review of the literature. Journal of Periodontology (2006)77, 545– 564
Qadri, T., Miranda, L., Tuner, J. & Gustafsson, A. The short-term effects of low-level lasers as adjunct therapy in the treatment of periodontal inflammation. Journal of Clinical Periodontology (2005) 32, 714–719
Walsh, L. J. The current status of low level laser therapy in dentistry. Part 1. Soft tissue applications. Australian Dental Journal (1997) 42, 247–254
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Smoking tobacco is probably the single most significant source of toxic chemical exposure to humans, and that affects many human organs .smoking is a major risk factor for various types of cancers.The specimenen compassed of two groups of voluntee rs: the group included 20 volunteers of smokers, the second group included14 volunteers of non-smokers as a control group. Surgical biopsy from oral buccal mucosa were taken and stained with ( P21,p27 clone) antibody by IHC, and we count the positive stained cells in two study groups to show if the gene p21,p27 is affected by cigarette smoking, and investigate the possibility of a mutation in it .statistical clear differences between the two groups . the control group is negative while the two groups was positive.
Although the use of Soft Laser appliances has become common in dental practice especially in the field of oral and maxillofacial surgery as an important method for controlling the edema that may occur after oral and maxillofacial surgery (as said by the manufacturing companies ),there are just a few neutral researches that deal scientifically with this subject, so that is our motive to do in this research .In this study, and between May 1996 and May 2003, 80 patients were carefully selected so 160 lower third molars were surgically extracted , the soft laser was applied on the left side and after that the results compared with the results of the right side operations which were not subjected to any method for controlling edema. The results were disappointing and the great advantages that were confirmed by the manufacturing companies were not true while the neutral comparative research emphasized that the usage of Soft laser treatment has no magical effect in reducing or preventing the occurrence of severe edema after the surgery of impacted lower third molars , so we want to warn every dentist to be careful when reading a research sponsored by the manufacturing companies of Soft laser appliances.
Recombinant human bone morphogenetic protein-2 (rhBMP-2 ) is effectively to regenerate defects of the maxillary and mandible bones. Such defects are sometimes caused by resection of oral squamous cell carcinoma (OSCC) yet the biologic effects of rhBMP-2 on this malignancy and its histological relations and the ability of invasion and metastasis are not fully clear. Aim of the study : this study aimed to investigate the effects of rhBMP2 on E-cadherin expression , which plays a pivotal role in the cellular adhesion through the adherent junctions.
Khat chewing is a deep-rooted habit in Yemen. It has many negative impacts on different body systems. The spread of khat chewing among adult males in Yemeni society needs special attention. Cathinone and cathine are the most stimulants of khat ing redients. Other ingredients could have other implication such as gastrointestinal carcinogenic tannins. the aim of this study is to Investigate chronic khatchewing effects on oral mucosa and the role of concurrent smoking.
Introduction: oral infection is one of the most common disturbances in the intensive care units ICUs, especially with the critical intubated patients. Application of oral care policy works as a very important action in preventing the infection. ADHA improved that using of Chlorhexidine Gloconate 0.12% and Povidone Iodine 1% solutions in oral care can contribute to preventing oral infection. Goal: The aim of the present study was to investigate the effect of applying oral care policy to the oral infection rate with intubated patients. Materials and Methods: The study was conducted at the intensive care units of AL-Basel Hospital (Tartous), a convent sample of 45 patients. Beck Oral Assessment Scale was used to assess the oral status and results after 72 hours of applying oral care policies for the two experimental groups and the control groups. Results: our results demonstrate the important of applying oral care policy, rate of infection decreased in the first control group (p= 0.000*) which received first oral care policy procedures (Chlorhexidine Gloconate 0.12%); it was (Povidone Iodine 1%) in the second control group (normal saline 0.9%) in the last control group. Conclusions and Recommendations: our present study results recommend applying oral care policy (Chlorhexidine Gloconate 0.12%, Povidone Iodine 1%) because of its affect in preventing oral infections for critical intubated patients.

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