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Capability of enamel matrix derivative to induce dentine after pulp capping in humans

تقييم مشتق القالب المينائي على تشكيل العاج بعد التغطية اللبية عند الإنسان

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 Publication date 2012
  fields Dentistry
and research's language is العربية
 Created by Shamra Editor




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Amelogenins from ameloblast play an important rule in differntiating odontoblasts in dental papilla, suggesting that amelogenins may associate with odontoblasts changes during development. Aim In the present study we have investigated the effects of enamel matrix derivative (EMD) on the healing of pulpal wound and formation of reperative dentin.

References used
Hermann BW. Dentinobliteran der Wurzelkanalc nach der Behandlung mit kalzuim. Zahnaiztl Rundschau 1930;39:888
Zander HA. Reaction of the pulp to calcium hydroxide. J Dent Res 1939;18:373-79
Horsted P, Sandergaard B, Thylstrup A, El Attar K, Fejerskov O. A retrospective study of direct pulp capping with calcium hydroxide compounds. Endod Dent Traumatol 1985;1:29-34
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Pulpectomy was performed on 100 primary teeth and the radiograph was exposed immediately post treatment to observe weather the root canal filling was: flush-undefiled or overfilled. Teeth were examined periodically, clinically and radio graphically to assess success of the treatment.
For controlling the release of Ketoprofen from matrix tablets, combinations between different polymers in different ratio were formulated. Aim: The aim of this study is to investigate the applicability of HPMC combination with Polymethacrylates (Eُudragit RS, RL & L100) for controlling the release of ketoprofen from matrix tablets. Four types of HPMC with different viscosities were tested in the study.
The research aims to evaluate the micro shear bond strength of the calcium silicate cement (Biodentine) and the glass ionomer cement (GIC) to dentine. The study was performed using upper or lower premolars, and samples were divided into six equal s ubgroups according to the time period (3 h, 1 day, 1 week, 2 weeks, 4 weeks, 8 weeks), in order to study changes in the values of shear bond strength with time. The comparative study showed that the success rate of adhesion in the Biodentine group was smaller than that in the GIC group for the tested premolars after 3 hours and one day, whereas the success rate in the Biodentine group was greater than that in the GIC group for the tested premolars after 8 weeks. Results showed a positive correlation between the mean values of shear bond strengths and the studied time in Biodentine group, which ranged from 1.49 ± 0.18 MPa at 3 hours to a maximum value of 2.65 ± 0.26 MPa after 8 weeks. While there was a negative correlation between the mean values and the studied time in the GIC group and values ranged from 3.02 ± 0.13 MPa at 3 hours and 2.06 ± 0.09 MPa at 8 weeks. The study showed the advantage of Biodentine compared with GIC in terms of micro-bonding to dentine, which can have a clinically significant importance in preventing the micro leakage and reducing bacterial contamination.

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