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Register a new userFetal Echocardiography in Diagnosing Congenital Heart Disease Prenatally
دور صدى القلب الجنيني في تشخيص العيوب القلبية الولادية في أثناء الحياة الرحمية
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Damascus University ورقة بحثية
Publication date
2012
fields
Medicine
and research's language is
العربية
Authors
سمير سرور( باحث )
Created by
Shamra Editor
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سمح استخدام تخطيط صدى القلب عند الجنين- الذي أصبح من السهل الحصول على كامل مقاطعه التقليدية بدءاً من الأسبوع 16 للحمل- بكشف معظم العيوب القلبية الولادية، هدف هذا البحث إلى تقييم دور تخطيط صدى القلب و دقته عند الجنين في كشف العيوب القلبية الولادية.
Prenatal detection of congenital heart disease is possible from the 16th week of pregnancy. the ideal time being the Midtrimester ,when the most cardiac abnormalities can be detected ,where all routine cross sectional views are easily obtainable. To evaluate the detection and accuracy of fetal echocardiography for congenital heart defects among high risk pregnancies.
References used
Lisa K. Hornberger‚ Stephen P.Sanders‚ Azaria J.J.T.Rein. Left Heart Obstructive Lesions The Midtrimester Fetus A Longitudinal Study. Circulation.1995;92:1531-1538
Lindsey D Allan. Echocardiographic Detection Of Congenital Heart Disease In The Fetus: Present And Future. Br Heart J. 1995;74:1030-1036
Juile Tan ‚ Norman H.Silverman‚ Juilen I.E. Hoffman. Cardiac Dimensions Determined By Cross-Sectional Echocardiography In The Normal Human Fetus from 18 Weeks To Term. Am J Cardiol .1992;70:1459-1467
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Background: longitudinal and radial systolic function are weakened by cardiac diseases and
longitudinal one is weakened first. Assessment of left ventricular LV systolic function is important
in management and prognosis of cardiac diseases. Mitral
annular displacement MAD is used to
assess LV longitudinal and global systolic function.
Objectives: To validate the accuracy of MAD assessed by Doppler tissue imaging DTI and
m-mode echocardiography MME as a surrogate for determination of LV systolic function in
pationts with ischemic heart disease and/or heart failure, and maybe easy and fast way instead of
conventional echocardiography assessment of LV function. This way permits to study the function
of LV longitudinal cardiac fibers function while the conventional ways of echocardiography
assesses the circumferential shortening.
Patients and methods: We studied a series of 96 patients (men and women) with (ischemic
heart diseases,heart failure) divided into three age groups and compared with another 59 healthy
age matched volunteers as a control group. We selected subjects from AL ASSAD hospital
/LATAKIA over the year 2014. A medical history, whole medical examination, ECG, conventional
echocardiography were made to each subject. Ejection fraction EF of LV, Doppler recording of the
mitral inflow, MME and pulse wave Doppler tissue imaging PW DTI data (from each four sites of
mitral annulus, anterior, septal, lateral and inferior) were obtained. Mean peak systolic velocity (S
wave), mean annular early diastolic velocity (e') by PW DTI and mean mitral annular displacement
(MAD) by MME were calculated by averaging of values measured at each annular site.
Results: MAD correlate well with LV EF, mean MAD < 11.275 mm determined by MME
has 85% sensitivity and 87.8% specificity and 85.8% accuracy for detection of LV EF < 50%, Mad
was low in patients with infarctions and lower in pationts with heart failure.
Conclusion: Mean MAD connect with a positive relationship with LV EF and can detect the
abnormal systolic motion on the long axis. That means the ability to detect the ischemia in early
stages.
Heart disease is the leading cause of death in the world over the past 10 years. Researchers have been using several data mining techniques to help health care
professionals in the diagnosis of heart disease. Decision Tree is one of the successful d
ata mining techniques used. However, most research has applied J4.8 Decision Tree, based on Gain Ratio and binary discretization. Gini Index
and Information Gain are two other successful types of Decision Trees that are less used in the diagnosis of heart disease. Also other discretization techniques, voting method, and reduced error pruning are known to produce
more accurate Decision Trees. This research investigates applying a range of techniques to different types of Decision Trees seeking better performance in heart disease diagnosis. A widely used benchmark data set is
used in this research. To evaluate the performance of the alternative Decision Trees the sensitivity, specificity, and accuracy are calculated. The research proposes a model that outperforms J4.8 Decision Tree and Bagging algorithm in the diagnosis of heart disease patients.
We present here a simplified method to perform Bidirectional
Glenn’s Cavo-Pulmonary Shunt (BDG) in which we use no
cardiopulmonary bypass (CPB) nor an intra-operative temporary shunt,
sometimes used on the belief that it lessens the developed intr
a-venous
congestion and pressure in the upper torso, intra-operatively. Our approach
springs from the idea that acute intra-venous congestion, resulting from the
application of vascular cross-clamp on the superior vena cava (SVC) during
operation, is being vented through abundant and numerous anatomic
venous anastomoses between the SVC system and the inferior vena cava
(IVC) system. It also springs from the conception that the brain of patients
with low arterial blood O2-saturation tolerates cerebral hypoxia better than
the normally functioning brain. Such hypoxia may ensue from the transient
low cerebral arterial blood flow, resulting in turn from the temporary intravenous
cerebral congestion (and related raised pressure) following SVC
clamping.
Aim of study: Evaluating the oral health status of children with congenital heart
disease in comparison with the healthy children in Lattakia city.
Materials and Methods: A total of 100 children aged between 5 and 12 years
attending the pediatric
clinic of AL-Assad Hospital-Lattakia were included. The study
group was consisted of 50 children diagnosed with heart disease. The control group was
consisted of 50 healthy children of the same age and gender. Dental caries, plaque,
gingivitis and developmental enamel defects were assessed for each child in the two
groups.
Results: Mean dmft, gingivitis and plaque were significantly higher in the cardiac
group as compared to the control group. Statistically, no significant differences were found
in the comparison between the prevalence of developmental enamel defects and mean
DMFT for the two groups.
Conclusion: Children with congenital heart disease had a poor oral health compared
to the healthy children, which increased the risk of susceptibility to bacteremia and
development of infective endocarditis. Therefore, dental care for children with heart
disease must be seriously considered at an early age when the first tooth erupts.
The present study aimed to early embryonic diagnose death in 46
bitchs. Blood samples were collected at the, 20th, 25th, 30th, 35th day
after ovulation.
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