This study aims to shorten the orthodontic treatment period
into,at least, half the length of time. It takes in order to reduce the
complaints of patients of the length of orthodontic treatment through
the induction of the secretion of prostagland
in E2 topically by
raising the inflammatory process via injection of vitally accepted
materials which are used routinely in daily dental practice,
Lidocaine 2% which leads to the increase of proportion of
osteoclasts and the occurrence of bone absorption in the injected
area ( the area of the tooth to be moved) .
This study was made at ALASSAD Hospital-TISHREEN University in-LATTAKIA
at the Department of Obestetrics and Gynecology in the period between 1/1/2013 and
1/1/2014. The number of patients the study was 190.Including140 cases have been holding
memb
rane stripping and 50 cases without membrane stripping.
According to Bishop –Scoring index we have estimated the uterine cervix in patients,
then a Membrane- Stripping was made.
Rate of response was 79.28% in cases of membrane stripping "then 54%in cases "
without membrane striping ". In most cases of response ,we need to do the membrane
stripping twice.Top of response was obtained when Bishop –Scoring index was between 4-
6 (Moderate ripening of the cervix).
Rate of Vaginal Delivery was 87.85% in cases of membrane stripping and 76%
without membrane stripping.
The complications were limited in the study group included:
1-Infection( 0.58%).
2-Bleeding 0.58%.
3-PROM 1.16%.
It means that Membrane Stripping was somehow safe.
This search included 150 pregnant women who had gestational age of 36 weeks or more, and had been admitted to the Department of Obstetrics and Gynecology at Al – Assad University Hospital in Lattakia for the spontaneous vaginal delivery during the st
udy period
( 1\1\2012 to 1\7\ 2013). Exclusion criteria were patients undergoing cesarean section, patients with placenta previa, or abruptio placenta, patients with hemoglobin<9 gm%, pregnancy-induced hypertension or pre eclampsia–eclampsia, grand multiparty, coagulation abnormalities, positive history of PPH, expensive hemorrhage or other medical disorders.
Patients were randomly divided into three groups: ( 1: uterine massage group, 2: 10 units oxytocin in 500 cc glucose 5% intravenously with delivery of the anterior sholder\ control group, 3: three 200µg rectal misoprostol tablets\study group).
No significant differences were observed between the groups regarding baseline characteristics. There was blood loss of ≥500 ml occurred in 18% in the first group, 6% in the second group, 8% in the third group. Routine use of 600 µg of rectal misoprostol was effective in reducing blood loss after delivery ل gm%, pregnancyts with hemoglobin}ergoing cesarean section, patients with placenta pre and g (RR 0.44 ; CI 0.32 – 1.53), but not as effective as intravenous oxytocin (RR 1.33 ; CI 0.4 – 3.39).
Although these were differences, they were not significant (No significant differences were observed between the control and study groups for the length of the third stage of labor, the estimated blood loss, the changes in Hb and Hct concentrations, need for additional uterotonics, manual removal of placenta, blood transfusion…..).
This dose of misoprostol and route of administration were well tolerated, and usual side effects such as shivering and fever were transient, resolved on their own, and were not threatening. Because PPH is the most significant direct cause of maternal mortality and because most of these maternal mortality occurs in low resource countries, misoprostol offers several advantages over oxytocin in such settings. It is formulated as a tablet, widely available and affordable, and it does not need require special storage conditions (i.e. it is stable at ambient room temperature and does not require specific conditions for transfer and has a shelf-life of several years). It also does not require any special skills, equipment, or facilities for its use. So misoprostol can fill a service delivery gap in settings where women and providers are unable to access oxytocin.ل gm%, pregnancyts with hemoglobin}ergoing cesarean section, patients with placenta pre and g
In very low concentrations, Prostaglandin E2 affects the electrical and contractile
activity of the smooth muscles of the gastric antrum, and this leads to a decrease
in the potential polarization of the membrane, and the appearance of muscle
cont
ractions. Both calcium and sodium ions play an important role in the
mechanism of the effect of prostaglandin E2 on this activity.
The smooth muscles of gastric fundus do not show any spontaneous activity.
Experiments have shown that prostaglandin E2 leads to the inhibition of the
contraction produced by stimulation, but has the opposite effect on the gastric
antrum. Calcium ions play an important role in this activity.
