Formaldehyde is classified by the World Health Organization (International Agency
for Research on Cancer) as a carcinogen in Group 1. The upper limit allowed for use in
cosmetic products as a preservative has to not exceed 0.2%. This study aims to
detect and
determine formaldehyde level in some cosmetic products available in the local market
using acetyl acetone method. Formaldehyde was detected in 77% of the studied cosmetic
products (49 samples) despite the fact that most of them were not labeled formaldehyde or
formaldehyde donor preservatives (about 70%). The amount of formaldehyde in keratin
samples were higher than the allowed limit (0.34% -11.73%) except one sample 0.18%. pH
decrease and temperature increase of keratin samples led to an increase of formaldehyde
level as a result of its release from preservatives.
The aim of this study was to control the content of some commercial products containing amino acid (Arginine) available in the local market in addition to other products containing creatine and protein. Three methods were used for quantitative determ
ination of amino acids Kjeldahl method depending on the total content of nitrogen, assay by the visible radiation using Spectrophotometer after ninhydrin derivatization and high performance liquid chromatography with pre-column O-phtadelaldehyde derivatization using fluorescence detector. There were no significant differences in the results obtained by the three used methods. The results revealed that dietary supplements containing creatine and protein were conform to the European pharmacopoeia specifications, regarding products containing arginine used as medication and locally manufactured, they were conform to pharmacopoeia specifications while the illegal dietary supplement containing arginine were not conform.
A new colorimetric analytical method was developed for determination of
Lisinopril in bulk and tablets .
The method is depended on derivatization chemical reaction between
Lisinopril and 4- nitrobenzene diazonium tetra fluoro borate in non
aqueou
s medium to give color derivatives with max. absorption at 293.8 nm
.
The resulting color was measured spectrophotometrically . The absorbance
concentration plots were recti linear over the range 5-50 μg /ml.
The method applied for determination the Lisinopril in Tablet, The
percentage recoveries was 98% ± 2.4.
The results obtained were in accordance with those found using the HPLC
standard method in Pharmacopoeia .
