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Squamous cell carcinoma SCC is an important malignancy in head and neck tumors , Its high stages resulting in poor survival because of metastasis–especially lymph nodes- and secondary tumors . lymph nodes LN have biological importance because of their immunity role as a base of immunity defensive lines and lymphatic fluid purification, Recently chemokine receptors have been reported to be correlated with many malignancies ,In particular CCR7.
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