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Objective: Evaluate sensitivity and specificity of nitrite test to urine culture(gold standard) for diagnosing urinary tract infection in patients with sickle cell anemia with urinary symptoms and signs. Methods: The study sample included 79 chi ldren aged 2 to 14 years with SCA presenting with fever (temperature >38°C),abdominal pain, urgency, dysuria or increased urinary frequency who referral to the general pediatric clinic and the children's ambulance department in Tishreen University Hospital in Lattakia during( 2016-2017). Midstream urine specimen was collected from children. Samples were subjected to nitrite test, culture and sensitivity. Results : There was significant bacteriuria in 17 (21.5%) children with SCA. A positive test for nitrite was obtained in 12 of the 17(70.5%) children. The nitrite test has a specificity of 95.2% in detecting bacteriuria, a sensitivity of 70.6%, a positive predictive value of 80% and a negative predictive value of 92%. A positive nitrite test was significantly associated with bacteriuria, while a negative test was also significantly associated with an absence of bacteriuria.
Objective: Breath holding spells is a common case in children aged 5months to 6 years, and often misinterpreted with epileptic seizures.we did clinical and epidemiological assessment for BHS.We documented the relation between sex, age, familial his tory and the episodes nature blue, pale or mixed. Materials & Methods: This was a cross-sectional study in which a total of 50 children with BHS, admitted to the out patient neuropediatric clinic 2013-2014. We took full medical history and did the investigations to eliminate the differential diagnosis. Results:Most patient were 7-24 month, we noticed parental consanguinity 87% and familial history in 56%.The spells were cyanotic 70%. Anger and pain were the more frequent risk factors 64%,60%.Anemia found in 58% of patient.Half of the patient have socioeconomic problems.And most of them from nuclear family 66%. Conclusion:The study mentioned the types of spells and the risk factors and the importance of look for anemia.
This study included 502 children between 0,5-15 years old. They were all subjected to duodenal biobsy for several reasons, and underwent investigations; Hb, MCV, MCH, MCHC and RDW. The prevalence of celiac disease among anemic children was higher than nonanemic patients (36,04% vs 12,14%). The mean duration of compliance was higher in both anemic children and celiac patients than in comparing groups .The mean levels of Hb,MCV,MCH and MCHC were lower in celiac group, while RDW was higher. Anemia was the most common presentation of celiac disease and it was seen in 77% among celiac children, while failure to thrive was detected in 43% of celiac group. Clinicians should consider celiac disease as a possible cause of anemia in all subjects with unexplained or refractory anemia
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